Similar studies for GEO DataSets (Select 200003699) - GEO DataSets

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Items: 2

Select item 2000036991.

DNA-Methyltransferases (DNMT) knockouts

(Submitter supplied) Alterations in DNA-methylation are a hallmark of human tumor cells. DNMT1 is expressed in three different splice variants and exhibits considerable preference for hemimethylated DNA and is therefore referred to as the maintenance methylase. DNMT3b is generally considered to be responsible for de novo methylation during embryonic development and probably also during tumor development. Recent studies using somatic knock-out of DNA-methyltransferases have shown a reduction in overall methylation and a re-expression of tumor suppressor genes. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL3050
14 Samples

Download data: GPR

Series

Accession:: GSE3699

ID:: 200003699

Select item 2000356632.

Oncogeneic KRAS Regulates BMP4 Expression in Colon Cancer

(Submitter supplied) Microarray analysis comparing SW480 cells treated with scramble siRNA control with SW480 cells treated with siRNA against mutant KrasV12.