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Items: 8

1.

BCL6 confers KRAS-mutant NSCLCs resistance to BET inhibitors

(Submitter supplied) We report that OTX015 upregulates BCL6 in KRAS-mutant NSCLC cells. Considering that both BCL6 and BET proteins regulate target genes by affecting transcription, we performed an RNA-seq experiment to identify downstream genes which response to OTX015. Retinal mRNA profiles of A549 cells treated with DMSO (0.1% for 6 hr) and OTX015 (1 μM for 6 hr) were generated by deep sequencing, in triplicate, using the SOLiD v4 sequencing platform. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
6 Samples
Download data: FPKM_TRACKING
Series
Accession:
GSE118645
ID:
200118645
2.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
3.

OTX_rep_3

Organism:
Homo sapiens
Source name:
A549
Platform:
GPL16791
Series:
GSE118645
Download data: FPKM_TRACKING
Sample
Accession:
GSM3335845
ID:
303335845
4.

OTX_rep_2

Organism:
Homo sapiens
Source name:
A549
Platform:
GPL16791
Series:
GSE118645
Download data: FPKM_TRACKING
Sample
Accession:
GSM3335844
ID:
303335844
5.

OTX_rep_1

Organism:
Homo sapiens
Source name:
A549
Platform:
GPL16791
Series:
GSE118645
Download data: FPKM_TRACKING
Sample
Accession:
GSM3335843
ID:
303335843
6.

DMSO_rep_3

Organism:
Homo sapiens
Source name:
A549
Platform:
GPL16791
Series:
GSE118645
Download data: FPKM_TRACKING
Sample
Accession:
GSM3335842
ID:
303335842
7.

DMSO_rep_2

Organism:
Homo sapiens
Source name:
A549
Platform:
GPL16791
Series:
GSE118645
Download data: FPKM_TRACKING
Sample
Accession:
GSM3335841
ID:
303335841
8.

DMSO_rep_1

Organism:
Homo sapiens
Source name:
A549
Platform:
GPL16791
Series:
GSE118645
Download data: FPKM_TRACKING
Sample
Accession:
GSM3335840
ID:
303335840
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Supplemental Content

db=gds|term=GSE118645[Accession]|query=11|qty=2|blobid=MCID_67366a0b5ff35f4f6719087c|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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