GSE111871[Accession] - GEO DataSets - NCBI

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Runx/Cbfβ complexes protect ILC2s from exhaustion during allergic airway inflammation

(Submitter supplied) Group 2 innate lymphoid cells (ILC2s) have tissue-resident competence and contribute to the pathogenesis of allergic diseases. Therefore, there should be mechanisms to maintain the capacity of ILC2s to produce TH2 cytokines under chronic inflammatory conditions. Here, we report that Runx proteins are essential to prevent exaggerated activation of ILC2, in part by antagonizing GATA-3 function at steady state. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL18480 GPL17021
30 Samples

Download data: TXT, WIG

Series

Accession:: GSE111871

ID:: 200111871

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000184802.

Illumina HiSeq 1500 (Mus musculus)

Organism:: Mus musculus

595 Series
10993 Samples

Platform

Accession:: GPL18480

ID:: 100018480

Select item 1000170213.

Illumina HiSeq 2500 (Mus musculus)

Organism:: Mus musculus

11075 Series
298785 Samples

Platform

Accession:: GPL17021

ID:: 100017021

Select item 3033872614.

Lung_ILC2_WT_IL2_7_33_input

Organism:: Mus musculus

Source name:: Lung ILC2

Platform:: GPL18480
Series:: GSE111871

Download data: WIG

Sample

Accession:: GSM3387261

ID:: 303387261

SRA Run Selector

Select item 3033872605.

Lung_ILC2_WT_IL2_7_33_ChIP-seq_K27me3_rp2

Organism:: Mus musculus

Source name:: Lung ILC2

Platform:: GPL18480
Series:: GSE111871

Download data: WIG

Sample

Accession:: GSM3387260

ID:: 303387260

SRA Run Selector

Select item 3033872596.

Lung_ILC2_WT_IL2_7_33_ChIP-seq_K27me3_rp1

Organism:: Mus musculus

Source name:: Lung ILC2

Platform:: GPL18480
Series:: GSE111871

Download data: WIG

Sample

Accession:: GSM3387259

ID:: 303387259

SRA Run Selector

Select item 3033872587.

Lung_ILC2_WT_IL2_7_33_ChIP-seq_K27ac_rp2

Organism:: Mus musculus

Source name:: Lung ILC2

Platform:: GPL18480
Series:: GSE111871

Download data: WIG

Sample

Accession:: GSM3387258

ID:: 303387258

SRA Run Selector

Select item 3033872578.

Lung_ILC2_WT_IL2_7_33_ChIP-seq_K27ac_rp1

Organism:: Mus musculus

Source name:: Lung ILC2

Platform:: GPL18480
Series:: GSE111871

Download data: WIG

Sample

Accession:: GSM3387257

ID:: 303387257

SRA Run Selector

Select item 3033872569.

Lung_ILC2_WT_IL2_7_33_ChIP-seq_R3_rp2

Organism:: Mus musculus

Source name:: Lung ILC2

Platform:: GPL18480
Series:: GSE111871

Download data: WIG

Sample

Accession:: GSM3387256

ID:: 303387256

SRA Run Selector

Select item 30338725510.

Lung_ILC2_WT_IL2_7_33_ChIP-seq_R3_rp1

Organism:: Mus musculus

Source name:: Lung ILC2

Platform:: GPL18480
Series:: GSE111871

Download data: WIG

Sample

Accession:: GSM3387255

ID:: 303387255

SRA Run Selector

Select item 30304299511.

Lung_ILC2_Cbfb-homo-PLZF-Cre_IL-33_RNA-seq_rpt_3

Organism:: Mus musculus

Source name:: Lung ILC2

Platform:: GPL17021
Series:: GSE111871

Download data: TXT

Sample

Accession:: GSM3042995

ID:: 303042995

SRA Run Selector

Select item 30338725412.

Lung_ILC2_WT_IL2_7_33_ChIP-seq_R1_rp2

Organism:: Mus musculus

Source name:: Lung ILC2

Platform:: GPL18480
Series:: GSE111871

Download data: WIG

Sample

Accession:: GSM3387254

ID:: 303387254

SRA Run Selector

Select item 30304299413.

Lung_ILC2_Cbfb-homo-PLZF-Cre_IL-33_RNA-seq_rpt_2

Organism:: Mus musculus

Source name:: Lung ILC2

Platform:: GPL17021
Series:: GSE111871

Download data: TXT

Sample

Accession:: GSM3042994

ID:: 303042994

SRA Run Selector

Select item 30338725314.

Lung_ILC2_WT_IL2_7_33_ChIP-seq_R1_rp1

Organism:: Mus musculus

Source name:: Lung ILC2

Platform:: GPL18480
Series:: GSE111871

Download data: WIG

Sample

Accession:: GSM3387253

ID:: 303387253

SRA Run Selector

Select item 30304299315.

Lung_ILC2_Cbfb-homo-PLZF-Cre_IL-33_RNA-seq_rpt_1

Organism:: Mus musculus

Source name:: Lung ILC2

Platform:: GPL17021
Series:: GSE111871

Download data: TXT

Sample

Accession:: GSM3042993

ID:: 303042993

SRA Run Selector

Select item 30338725216.

Lung_ILC2_WT_IL2_7_33_ChIP-seq_gata3_rp2

Organism:: Mus musculus

Source name:: Lung ILC2

Platform:: GPL18480
Series:: GSE111871

Download data: WIG

Sample

Accession:: GSM3387252

ID:: 303387252

SRA Run Selector

Select item 30304299217.

Lung_ILC2_Cbfb-het-PLZF-Cre_IL33_RNA-seq_rpt_3

Organism:: Mus musculus

Source name:: Lung ILC2

Platform:: GPL17021
Series:: GSE111871

Download data: TXT

Sample

Accession:: GSM3042992

ID:: 303042992

SRA Run Selector

Select item 30338725118.

Lung_ILC2_WT_IL2_7_33_ChIP-seq_gata3_rp1

Organism:: Mus musculus

Source name:: Lung ILC2

Platform:: GPL18480
Series:: GSE111871

Download data: WIG

Sample

Accession:: GSM3387251

ID:: 303387251

SRA Run Selector

Select item 30304299119.

Lung_ILC2_Cbfb-het-PLZF-Cre_IL33_RNA-seq_rpt_2

Organism:: Mus musculus

Source name:: Lung ILC2

Platform:: GPL17021
Series:: GSE111871

Download data: TXT

Sample

Accession:: GSM3042991

ID:: 303042991

SRA Run Selector

Select item 30338725020.

Lung_ILC2_WT_IL2_7_33_ChIP-seq_Cbfb_rp2

Organism:: Mus musculus

Source name:: Lung ILC2

Platform:: GPL18480
Series:: GSE111871

Download data: WIG

Sample

Accession:: GSM3387250

ID:: 303387250

SRA Run Selector

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