3595 3705 3872 3886 3938 3941 3945 3984 4007 4008 4043 4069 4079 4091 - GEO DataSets - NCBI

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Select item 59481.

Full record GDS5948

Zipper-interacting protein kinase deficiency effect on coronary artery smooth muscle cells in vitro

Analysis of cultured vascular smooth muscle cells following knockdown of zipper-interacting protein kinase (ZIPK). ZIPK is phosphorylated and activated by Rho-associated kinase 1 (ROCK1). These results, together with those from GDS5659, provide further insight into ROCK1 and ZIPK functions.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 genotype/variation sets

Platform:: GPL6244
Series:: GSE56819
6 Samples

Download data: CEL

DataSet

Accession:: GDS5948

ID:: 5948

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 56592.

Full record GDS5659

Rho-associated kinase deficiency effect on coronary artery smooth muscle cells in vitro

Analysis of cultured vascular smooth muscle cells following knockdown of Rho-associated kinase 1 (ROCK1). ROCK1 phosphorylates and activates zipper-interacting protein kinase (ZIPK). These results, together with those from GDSxxxx, provide further insight into ROCK1 and ZIPK functions.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 genotype/variation sets

Platform:: GPL6244
Series:: GSE56819
6 Samples

Download data: CEL

DataSet

Accession:: GDS5659

ID:: 5659

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 56103.

Full record GDS5610

Heritable pulmonary arterial hypertension: cardiac right ventricular wall

Analysis of biopsies of right ventricle (RV) from patients with pulmonary arterial hypertension (PAH) with bone morphogenetic protein receptor type II (BMPR2) mutation. Results provide insight into molecular mechanisms underlying the metabolic effects of mutant BMPR2 in PAH RVs.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 3 disease state sets

Platform:: GPL6244
Series:: GSE67492
6 Samples

Download data: CEL

DataSet

Accession:: GDS5610

ID:: 5610

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 58054.

Full record GDS5805

Peptidyl-prolyl cis/trans isomerase Pin1 deficiency effect on prostate cancer cells

Analysis of prostate cancer (PC) cell lines LNCap (androgen-dependent) and DU145 (androgen-independent) following siRNA-mediated knockdown of Peptidyl-prolyl cis/trans isomerase Pin1. Results provide insight into molecular mechanisms underlying Pin1 modulation of both PC two cell lines.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 cell line, 3 protocol sets

Platform:: GPL6244
Series:: GSE67457
6 Samples

Download data: CEL

DataSet

Accession:: GDS5805

ID:: 5805

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 58125.

Full record GDS5812

Staphylococcal alpha-toxin effect on airway epithelial cells

Analysis of bronchial epithelial cell lines 16HBE14o- (Hla-susceptible) and S9 (Hla-resistant) treated with S. aureus recombinant alpha-toxin (rHla) for 2 hrs. Results provide insight into molecular mechanisms underlying cell type-specific responses of airway epithelial cells to alpha-toxin.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 agent, 2 cell line sets

Platform:: GPL6244
Series:: GSE65018
8 Samples

Download data: CEL

DataSet

Accession:: GDS5812

ID:: 5812

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 58156.

Full record GDS5815

Sunitinib effect on renal cancer xenograft tumors

Analysis of Kyoto University Renal Cancer (KURC) xenograft tumor models, KURC1, KURC2, KURC3, treated with sunitinib, a small molecule inhibitor of receptor tyrosine kinases that is used to treat RC. Results provide insight into molecular mechanisms underlying acquired sunitinib resistance in RC.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 agent, 3 disease state, 3 individual sets

Platform:: GPL6244
Series:: GSE66346
9 Samples

Download data: CEL

DataSet

Accession:: GDS5815

ID:: 5815

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 58117.

Full record GDS5811

TGFβ1 effect on gingival fibroblasts pretreated with TGFβ-associated kinase 1 inhibitor 5Z-7-Oxozeanol

Analysis of cultured gingival fibroblasts pre-treated with TGFβ-associated kinase 1 (TAK1) inhibitor (5Z)-7-Oxozeanol for 45 min prior to treatment with TGFβ1. Results provide insight into the extent to which TAK1 mediates fibroproliferative responses in gingival fibroblasts in response to TGFβ1.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 agent, 2 protocol sets

Platform:: GPL6244
Series:: GSE65069
8 Samples

Download data: CEL

DataSet

Accession:: GDS5811

ID:: 5811

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 58108.

Full record GDS5810

Hypoxia effect on von Hippel Lindau-overexpressing renal cell carcinoma cells

Analysis of renal cell carcinoma (RCC) 786-O cells transfected with von Hippel Lindau (VHL)-overexpression vector and cultured under hypoxia conditions (1% O2) for 24 hours. Results provide insight into overlap and differences of VHL- and hypoxia-dependent molecular alterations in RCC.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 protocol, 2 stress sets

Platform:: GPL6244
Series:: GSE65168
8 Samples

Download data: CEL

DataSet

Accession:: GDS5810

ID:: 5810

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 54279.

Full record GDS5427

Osteoarthritic acetabular labrum 3-D culture

Analysis of osteoarthritic labrum cells cultured for 7 days in a 3-dimensional alginate bead system. The acetabular labrum is a fibrocartilaginous structure that seals the hip joint. Results provide insight into hip OA-associated molecular changes in acetabular labrum cells.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state, 8 individual sets

Platform:: GPL6244
Series:: GSE60762
8 Samples

Download data: CEL

DataSet

Accession:: GDS5427

ID:: 5427

PubMed Similar studies GEO Profiles Analyze DataSet

Select item 544010.

Full record GDS5440

Androgen effect on carboxyl terminal-binding protein 2-deficient prostate cancer cell line

Analysis of androgen receptor (AR)-positive LNCaP prostate cancer cells depleted for carboxyl terminal-binding protein 2 (CTBP2) then treated with the androgen, dihydrotestosterone (DHT). Results provide insight into the molecular effects of CtBP2 knockdown on AR-mediated gene regulation.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 agent, 4 genotype/variation sets

Platform:: GPL6244
Series:: GSE58309
10 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS5440

ID:: 5440

PubMed Similar studies GEO Profiles Analyze DataSet

Select item 560611.

Full record GDS5606

Androgen effect on runt-related transcription factor 1-deficient prostate cancer cell line

Analysis of androgen receptor (AR)-positive prostate cancer (PC) LNCaP cells depleted for runt-related transcription factor (RUNX1) by siRUNX1 transfection then treated with 10nM dihydrotestosterone (DHT). Results provide insight into the role of RUNX1 in AR-dependent PC.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 agent, 2 genotype/variation sets

Platform:: GPL6244
Series:: GSE62454
4 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS5606

ID:: 5606

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 591412.

Full record GDS5914

YAP transcriptional regulator depletion effect on endothelial cells

Analysis of umbilical vein endothelial HUVEC cells depleted for the transcriptional regulator YAP. YAP binds to the SH3 domain of the transcriptional activator Yes. Results provide insight into the role of YAP in endothelial cell proliferation.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 3 agent, 2 protocol sets

Platform:: GPL6244
Series:: GSE61989
12 Samples

Download data: CEL

DataSet

Accession:: GDS5914

ID:: 5914

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 536613.

Full record GDS5366

Cultivated amniotic membrane expanded limbal epithelium

Analysis of amniotic membrane-expanded limbal epithelium (AMLE) and corneal epithelium (CE). AMLE transplantation in place of donor CE significantly improves outcome in severe limbal stem cell deficiency cases. Results provide insight into molecular processes which characterize AMLE and CE tissues.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 growth protocol, 2 tissue sets

Platform:: GPL6244
Series:: GSE56421
6 Samples

Download data: CEL

DataSet

Accession:: GDS5366

ID:: 5366

PubMed Similar studies GEO Profiles Analyze DataSet

Select item 517114.

Full record GDS5171

Supraclavicular and subcutaneous adipose tissue progenitor cells

Analysis of progenitor cells isolated from paired biopsies of deep neck and subcutaneous neck adipose tissue from patients undergoing neck surgery. Results provide insight into the molecular mechanisms underlying the differences between white and brown progenitor cells.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 cell type, 6 individual sets

Platform:: GPL6244
Series:: GSE54280
12 Samples

Download data: CEL

DataSet

Accession:: GDS5171

ID:: 5171

PubMed Similar studies GEO Profiles Analyze DataSet

Select item 528715.

Full record GDS5287

SMRT depleted breast cancer cell line response to estradiol: time course

Analysis of ER-alpha+ MCF7 breast cancer cells depleted for the silencing mediator of retinoic acid and thyroid hormone receptor (SMRT). SMRT depleted cells examined 4 and 24 hours following treatment with estradiol. Results provide insight into the role of SMRT in breast cancer progression.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 agent, 2 protocol, 2 time sets

Platform:: GPL6244
Series:: GSE57935
24 Samples

Download data: CEL

DataSet

Accession:: GDS5287

ID:: 5287

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 538416.

Full record GDS5384

Interferon-gamma effect on peripheral blood monocyte-derived dendritic cells

Analysis of monocyte-derived dendritic cells (moDC) treated with granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin (IL)-4 or GM-CSF, IL-4 and interferon (IFN)-γ for 6d. Results provide insight into effects of IFN-γ on differentiation and maturation of peripheral blood moDC.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 4 individual, 2 protocol sets

Platform:: GPL6244
Series:: GSE47621
8 Samples

Download data: CEL

DataSet

Accession:: GDS5384

ID:: 5384

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 509717.

Full record GDS5097

Salmonella type III secretion effector SteA effect on epithelial cells

Analysis of HeLa epithelial cells stably-transfected with a SteA-3xFLAG fusion construct. Salmonella effector SteA is a substrate for both type III secretion systems which are essential for virulence. Results provide insight into the role of SteA during infections.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 3 cell line, 2 protocol sets

Platform:: GPL6244
Series:: GSE51043
9 Samples

Download data: CEL

DataSet

Accession:: GDS5097

ID:: 5097

PubMed Similar studies GEO Profiles Analyze DataSet

Select item 537818.

Full record GDS5378

Peroxisome proliferator-activated receptor δ (PPARδ) activation effect on cultured myotubes

Analysis of musculus obliquus internus myotubes treated with PPARδ agonist GW501516 for 96hrs. PPARs regulate lipid utilization and storage. PPARδ is the most abundant PPAR subtype in skeletal muscle. Results provide insight into the molecular effects of PPARδ activation on myotubes.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 agent, 4 individual sets

Platform:: GPL6244
Series:: GSE40789
8 Samples

Download data: CEL

DataSet

Accession:: GDS5378

ID:: 5378

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 496819.

Full record GDS4968

Monoclonal gammopathies: bone marrow plasma cells

Analysis of plasma cells from patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering multiple myeloma (MM), or MM. MM is consistently preceded by MGUS/SMM. Results provide insight into molecular mechanisms underlying the transformation from precursor disease to MM.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 4 disease state sets

Platform:: GPL6244
Series:: GSE47552
99 Samples

Download data: CEL

DataSet

Accession:: GDS4968

ID:: 4968

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 508520.

Full record GDS5085

Oncogenic BRAF harboring melanoma cell line response to BRAF inhibition

Analysis of A375 melanoma cells harboring the BRAF V600E oncogenic mutation following treatment with the BRAF inhibitor vemurafenib. Results provide insight into the role of the BRAF V600E oncogene in the pathogenesis of melanoma.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 agent sets

Platform:: GPL6244
Series:: GSE42872
6 Samples

Download data: CEL

DataSet

Accession:: GDS5085

ID:: 5085

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

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