ZNF750 silencing effect on differentiated keratinocytes
Summary:
Analysis of ZNF750-silenced HaCaT keratinocytes (KCs) at day 12 of calcium-induced differentiation. ZNF750 knockdown in HaCaT KCs leads to sustained cell proliferation and decreased apoptosis. Results provide insight into molecular mechanisms underlying keratinocyte terminal differentiation.
GPL6244:
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
Cohen I, Birnbaum RY, Leibson K, Taube R et al. ZNF750 is expressed in differentiated keratinocytes and regulates epidermal late differentiation genes. PLoS One 2012;7(8):e42628. PMID: 22936986
