Mammary epithelial cell line 184A1 response to dual-pulse epidermal growth factor stimulation: time course
Summary:
Analysis of 184A1 mammary epithelial cells pulsed once or twice with epidermal growth factor (EGF). Normal cells require continuous exposure to growth factors to cross a restriction point and commit to cell-cycle progression. Results provide insight into molecular events regulating S phase entry.
GPL6244:
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
Zwang Y, Sas-Chen A, Drier Y, Shay T et al. Two phases of mitogenic signaling unveil roles for p53 and EGR1 in elimination of inconsistent growth signals. Mol Cell 2011 May 20;42(4):524-35. PMID: 21596316