C-peptide effect on streptozotocin-induced type 1 diabetes: kidney proximal tubular cells
Summary:
Analysis of kidney proximal tubular cells of streptozotocin-induced, type 1 diabetes (T1D) rats treated with C-peptide for 2 hours. Proinsulin C-peptide exerts renoprotective effects in T1D. Results provide insight into molecular mechanisms underlying the protective effects of C-peptide.
GPL6247:
[RaGene-1_0-st] Affymetrix Rat Gene 1.0 ST Array [transcript (gene) version]
Citation:
Lindahl E, Nordquist L, Müller P, El Agha E et al. Early transcriptional regulation by C-peptide in freshly isolated rat proximal tubular cells. Diabetes Metab Res Rev 2011 Oct;27(7):697-704. PMID: 21618400
