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Status |
Public on Jul 27, 2011 |
Title |
C-peptide regulates early transcription in rat proximal tubular cells |
Organism |
Rattus norvegicus |
Experiment type |
Expression profiling by array
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Summary |
C-peptide exerts beneficial effects on glomerular hyperfiltration in type I diabetic patients. As C-peptide localizes to the nucleus, we investigated the transcriptional activities of C-peptide in proximal tubular cells isolated from diabetic rats.
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Overall design |
Two groups of proximal tubular cells isolated from type I diabetic rats: 1 treated with C-peptide, and 1 untreated. 2-3 replicates per group.
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Contributor(s) |
Lindahl E, Nordquist L, Müller P, El Agha E, Friederich M, Dahlman-Wright K, Palm F, Jörnvall H |
Citation(s) |
21618400 |
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Submission date |
Oct 13, 2010 |
Last update date |
Nov 06, 2013 |
Contact name |
Emma Lindahl |
E-mail(s) |
emmalindahl@gmail.com
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Organization name |
Karolinska Institutet
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Street address |
Scheeles väg 2
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City |
Stockholm |
ZIP/Postal code |
17177 |
Country |
Sweden |
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Platforms (1) |
GPL6247 |
[RaGene-1_0-st] Affymetrix Rat Gene 1.0 ST Array [transcript (gene) version] |
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Samples (5)
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Relations |
BioProject |
PRJNA132257 |