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Metastatic Pancreatic Neuroendocrine Carcinoma

MedGen UID:
1652568
•Concept ID:
C4727009
•
Neoplastic Process

Definition

Pancreatic neuroendocrine carcinoma that has spread from the original site of growth to another anatomic site. [from NCI]

Professional guidelines

PubMed

Surgical resection of the primary tumor leads to prolonged survival in metastatic pancreatic neuroendocrine carcinoma.
Feng T, Lv W, Yuan M, Shi Z, Zhong H, Ling S
World J Surg Oncol 2019 Mar 21;17(1):54. doi: 10.1186/s12957-019-1597-5. PMID: 30898132Free PMC Article

Recent clinical studies

Etiology

Surgical resection of the primary tumor leads to prolonged survival in metastatic pancreatic neuroendocrine carcinoma.
Feng T, Lv W, Yuan M, Shi Z, Zhong H, Ling S
World J Surg Oncol 2019 Mar 21;17(1):54. doi: 10.1186/s12957-019-1597-5. PMID: 30898132Free PMC Article
The prognostic influence of the proliferative discordance in metastatic pancreatic neuroendocrine carcinoma revealed by peptide receptor radionuclide therapy: Case report and review of literature.
Montanier N, Joubert-Zakeyh J, Pétorin C, Montoriol PF, Maqdasy S, Kelly A
Medicine (Baltimore) 2017 Feb;96(6):e6062. doi: 10.1097/MD.0000000000006062. PMID: 28178157Free PMC Article
Detection of the CD56+/CD45- immunophenotype by flow cytometry in neuroendocrine malignancies.
Bryson GJ, Lear D, Williamson R, Wong RC
J Clin Pathol 2002 Jul;55(7):535-7. doi: 10.1136/jcp.55.7.535. PMID: 12101203Free PMC Article

Diagnosis

The Eighth Edition of the American Joint Committee on Cancer Distant Metastases Stage Classification for Metastatic Pancreatic Neuroendocrine Tumors Might Be Feasible for Metastatic Pancreatic Ductal Adenocarcinomas.
Wen J, Chen J, Liu D, Xu X, Fan M, Zhang Z
Neuroendocrinology 2020;110(5):364-376. Epub 2019 Jul 30 doi: 10.1159/000502382. PMID: 31357196
The prognostic influence of the proliferative discordance in metastatic pancreatic neuroendocrine carcinoma revealed by peptide receptor radionuclide therapy: Case report and review of literature.
Montanier N, Joubert-Zakeyh J, Pétorin C, Montoriol PF, Maqdasy S, Kelly A
Medicine (Baltimore) 2017 Feb;96(6):e6062. doi: 10.1097/MD.0000000000006062. PMID: 28178157Free PMC Article
Pancreatic panniculitis.
Mahawish K, Iyasere IT
BMJ Case Rep 2014 Aug 22;2014 doi: 10.1136/bcr-2014-204290. PMID: 25150233Free PMC Article
Detection of the CD56+/CD45- immunophenotype by flow cytometry in neuroendocrine malignancies.
Bryson GJ, Lear D, Williamson R, Wong RC
J Clin Pathol 2002 Jul;55(7):535-7. doi: 10.1136/jcp.55.7.535. PMID: 12101203Free PMC Article

Therapy

The prognostic influence of the proliferative discordance in metastatic pancreatic neuroendocrine carcinoma revealed by peptide receptor radionuclide therapy: Case report and review of literature.
Montanier N, Joubert-Zakeyh J, Pétorin C, Montoriol PF, Maqdasy S, Kelly A
Medicine (Baltimore) 2017 Feb;96(6):e6062. doi: 10.1097/MD.0000000000006062. PMID: 28178157Free PMC Article
Treatment of High-Grade Metastatic Pancreatic Neuroendocrine Carcinoma with FOLFIRINOX.
Zhu J, Strosberg JR, Dropkin E, Strickler JH
J Gastrointest Cancer 2015 Jun;46(2):166-9. doi: 10.1007/s12029-015-9689-0. PMID: 25662891

Prognosis

The Eighth Edition of the American Joint Committee on Cancer Distant Metastases Stage Classification for Metastatic Pancreatic Neuroendocrine Tumors Might Be Feasible for Metastatic Pancreatic Ductal Adenocarcinomas.
Wen J, Chen J, Liu D, Xu X, Fan M, Zhang Z
Neuroendocrinology 2020;110(5):364-376. Epub 2019 Jul 30 doi: 10.1159/000502382. PMID: 31357196
Surgical resection of the primary tumor leads to prolonged survival in metastatic pancreatic neuroendocrine carcinoma.
Feng T, Lv W, Yuan M, Shi Z, Zhong H, Ling S
World J Surg Oncol 2019 Mar 21;17(1):54. doi: 10.1186/s12957-019-1597-5. PMID: 30898132Free PMC Article
The prognostic influence of the proliferative discordance in metastatic pancreatic neuroendocrine carcinoma revealed by peptide receptor radionuclide therapy: Case report and review of literature.
Montanier N, Joubert-Zakeyh J, Pétorin C, Montoriol PF, Maqdasy S, Kelly A
Medicine (Baltimore) 2017 Feb;96(6):e6062. doi: 10.1097/MD.0000000000006062. PMID: 28178157Free PMC Article
Treatment of High-Grade Metastatic Pancreatic Neuroendocrine Carcinoma with FOLFIRINOX.
Zhu J, Strosberg JR, Dropkin E, Strickler JH
J Gastrointest Cancer 2015 Jun;46(2):166-9. doi: 10.1007/s12029-015-9689-0. PMID: 25662891

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