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Abnormality of Krebs cycle metabolism

MedGen UID:
867422
Concept ID:
C4021795
Finding
Synonyms: Abnormality of citric acid cycle; Abnormality of the tricarboxylic cycle
 
HPO: HP:0000816

Definition

An abnormality of the tricarboxylic acid cycle. [from HPO]

Professional guidelines

PubMed

Liu J, Bai X, Zhang M, Wu S, Xiao J, Zeng X, Li Y, Zhang Z
Clin Transl Oncol 2024 Feb;26(2):338-351. Epub 2023 Jul 21 doi: 10.1007/s12094-023-03278-3. PMID: 37477784
Ebertowska A, Ludkiewicz B, Klejbor I, Melka N, Moryś J
Folia Morphol (Warsz) 2020;79(2):191-197. Epub 2020 Feb 19 doi: 10.5603/FM.a2020.0020. PMID: 32073132
Sherlock S, Parbhoo SP
Postgrad Med J 1971 Jul;47(549):493-8. doi: 10.1136/pgmj.47.549.493. PMID: 4934637Free PMC Article

Recent clinical studies

Etiology

Zhou YF, Hou YY, Ban Q, Zhang ML, Huang T, Ma B, Shi L, Zhang Q
Andrology 2023 Oct;11(7):1303-1319. Epub 2023 Mar 20 doi: 10.1111/andr.13412. PMID: 36841993
Kantorovich V, Pacak K
F1000Res 2018;7 Epub 2018 Sep 20 doi: 10.12688/f1000research.14568.1. PMID: 30345003Free PMC Article
Bloomgarden Z
J Diabetes 2018 May;10(5):350-352. Epub 2018 Feb 13 doi: 10.1111/1753-0407.12645. PMID: 29369529
Björklund P, Pacak K, Crona J
J Intern Med 2016 Dec;280(6):559-573. Epub 2016 May 10 doi: 10.1111/joim.12507. PMID: 27165774Free PMC Article
Zeviani M, Bonilla E, DeVivo DC, DiMauro S
Neurol Clin 1989 Feb;7(1):123-56. PMID: 2646519

Diagnosis

Bertero E, Nickel A, Kohlhaas M, Hohl M, Sequeira V, Brune C, Schwemmlein J, Abeßer M, Schuh K, Kutschka I, Carlein C, Münker K, Atighetchi S, Müller A, Kazakov A, Kappl R, von der Malsburg K, van der Laan M, Schiuma AF, Böhm M, Laufs U, Hoth M, Rehling P, Kuhn M, Dudek J, von der Malsburg A, Prates Roma L, Maack C
Circulation 2021 Nov 23;144(21):1694-1713. Epub 2021 Oct 14 doi: 10.1161/CIRCULATIONAHA.121.053755. PMID: 34648376
Kantorovich V, Pacak K
F1000Res 2018;7 Epub 2018 Sep 20 doi: 10.12688/f1000research.14568.1. PMID: 30345003Free PMC Article
Mascalchi M, Montomoli M, Guerrini R
Essays Biochem 2018 Jul 20;62(3):409-421. doi: 10.1042/EBC20170109. PMID: 30030366
Bloomgarden Z
J Diabetes 2018 May;10(5):350-352. Epub 2018 Feb 13 doi: 10.1111/1753-0407.12645. PMID: 29369529
Naviaux RK
Mitochondrion 2014 May;16:7-17. Epub 2013 Aug 24 doi: 10.1016/j.mito.2013.08.006. PMID: 23981537

Therapy

Khan MA, Zubair H, Anand S, Srivastava SK, Singh S, Singh AP
Cancer Lett 2020 Mar 31;473:176-185. Epub 2020 Jan 7 doi: 10.1016/j.canlet.2020.01.003. PMID: 31923436Free PMC Article
Bloomgarden Z
J Diabetes 2018 May;10(5):350-352. Epub 2018 Feb 13 doi: 10.1111/1753-0407.12645. PMID: 29369529
Tella SH, Taïeb D, Pacak K
Eur J Cancer 2017 Nov;86:1-4. Epub 2017 Sep 22 doi: 10.1016/j.ejca.2017.08.023. PMID: 28946040Free PMC Article
Caudarella R, Vescini F
Arch Ital Urol Androl 2009 Sep;81(3):182-7. PMID: 19911682
Sherlock S, Parbhoo SP
Postgrad Med J 1971 Jul;47(549):493-8. doi: 10.1136/pgmj.47.549.493. PMID: 4934637Free PMC Article

Prognosis

Song X, Pickel L, Sung HK, Scholey J, Pei Y
Int J Mol Sci 2024 Jun 29;25(13) doi: 10.3390/ijms25137173. PMID: 39000280Free PMC Article
Liu J, Bai X, Zhang M, Wu S, Xiao J, Zeng X, Li Y, Zhang Z
Clin Transl Oncol 2024 Feb;26(2):338-351. Epub 2023 Jul 21 doi: 10.1007/s12094-023-03278-3. PMID: 37477784
Björklund P, Pacak K, Crona J
J Intern Med 2016 Dec;280(6):559-573. Epub 2016 May 10 doi: 10.1111/joim.12507. PMID: 27165774Free PMC Article
Yang OC, Maxwell PH, Pollard PJ
Kidney Int 2013 Oct;84(4):667-81. Epub 2013 Jul 3 doi: 10.1038/ki.2013.245. PMID: 23823604
Linehan WM, Ricketts CJ
Semin Cancer Biol 2013 Feb;23(1):46-55. Epub 2012 Jun 13 doi: 10.1016/j.semcancer.2012.06.002. PMID: 22705279Free PMC Article

Clinical prediction guides

Córdoba-Jover B, Ribera J, Portolés I, Lecue E, Rodriguez-Vita J, Pérez-Sisqués L, Mannara F, Solsona-Vilarrasa E, García-Ruiz C, Fernández-Checa JC, Casals G, Rodríguez-Revenga L, Álvarez-Mora MI, Arteche-López A, Díaz de Bustamante A, Calvo R, Pujol A, Azkargorta M, Elortza F, Malagelada C, Pinyol R, Huguet-Pradell J, Melgar-Lesmes P, Jiménez W, Morales-Ruiz M
Liver Int 2023 Aug;43(8):1822-1836. Epub 2023 Jun 14 doi: 10.1111/liv.15640. PMID: 37312667
Bloomgarden Z
J Diabetes 2018 May;10(5):350-352. Epub 2018 Feb 13 doi: 10.1111/1753-0407.12645. PMID: 29369529
Bar-Or D, Carrick M, Tanner A 2nd, Lieser MJ, Rael LT, Brody E
J Crit Care 2018 Feb;43:197-201. Epub 2017 Sep 8 doi: 10.1016/j.jcrc.2017.09.012. PMID: 28915394
Krzysztoń-Russjan J
Postepy Hig Med Dosw (Online) 2016 Dec 30;70(0):1331-1342. doi: 10.5604/17322693.1227557. PMID: 28100843
Yang OC, Maxwell PH, Pollard PJ
Kidney Int 2013 Oct;84(4):667-81. Epub 2013 Jul 3 doi: 10.1038/ki.2013.245. PMID: 23823604

Recent systematic reviews

De Spiegeleer M, De Paepe E, Van Meulebroek L, Gies I, De Schepper J, Vanhaecke L
Mol Med 2021 Nov 6;27(1):145. doi: 10.1186/s10020-021-00394-0. PMID: 34742239Free PMC Article

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