U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Type I Endometrial Adenocarcinoma

MedGen UID:
311390
•Concept ID:
C1519719
•
Neoplastic Process

Definition

A classification of primary endometrial adenocarcinomas that refers to endometrioid adenocarcinoma and mucinous adenocarcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVType I Endometrial Adenocarcinoma

Professional guidelines

PubMed

International Endocervical Adenocarcinoma Criteria and Classification (IECC): A New Pathogenetic Classification for Invasive Adenocarcinomas of the Endocervix.
Stolnicu S, Barsan I, Hoang L, Patel P, Terinte C, Pesci A, Aviel-Ronen S, Kiyokawa T, Alvarado-Cabrero I, Pike MC, Oliva E, Park KJ, Soslow RA
Am J Surg Pathol 2018 Feb;42(2):214-226. doi: 10.1097/PAS.0000000000000986. PMID: 29135516Free PMC Article
Effectiveness of aromatase inhibitors in the treatment of advanced endometrial adenocarcinoma.
Bogliolo S, Gardella B, Dominoni M, Musacchi V, Cassani C, Zanellini F, De Silvestri A, Gaggero CR, Babilonti L, Spinillo A
Arch Gynecol Obstet 2016 Apr;293(4):701-8. Epub 2015 Dec 15 doi: 10.1007/s00404-015-3974-9. PMID: 26671487
The diagnosis and treatment of endometrial cancer: progress and controversies.
Denschlag D, Ulrich U, Emons G
Dtsch Arztebl Int 2010 Aug;108(34-35):571-7. Epub 2010 Aug 29 doi: 10.3238/arztebl.2011.0571. PMID: 21904591Free PMC Article

Recent clinical studies

Etiology

Quality of life in patients affected by endometrial cancer: comparison among laparotomy, laparoscopy and vaginal approach.
Berretta R, Gizzo S, Noventa M, Marrazzo V, Franchi L, Migliavacca C, Michela M, Merisio C, Modena AB, Patrelli TS
Pathol Oncol Res 2015 Jul;21(3):811-6. Epub 2015 Jan 10 doi: 10.1007/s12253-014-9895-2. PMID: 25573595
HER-2/neu is an independent prognostic factor in type I endometrial adenocarcinoma.
Kalogiannidis I, Petousis S, Bobos M, Margioula-Siarkou C, Topalidou M, Papanikolaou A, Vergote I, Agorastos T
Arch Gynecol Obstet 2014 Dec;290(6):1231-7. Epub 2014 Jul 15 doi: 10.1007/s00404-014-3333-2. PMID: 25022554
Estrogen receptor-regulated microRNAs contribute to the BCL2/BAX imbalance in endometrial adenocarcinoma and precancerous lesions.
Zhang R, He Y, Zhang X, Xing B, Sheng Y, Lu H, Wei Z
Cancer Lett 2012 Jan 28;314(2):155-65. Epub 2011 Sep 29 doi: 10.1016/j.canlet.2011.09.027. PMID: 22014978
Clinicopathological and molecular analysis of endometrial carcinoma associated with tamoxifen.
Turbiner J, Moreno-Bueno G, Dahiya S, Sánchez-Estevez C, Hardisson D, Prat J, Oliva E, Palacios J
Mod Pathol 2008 Aug;21(8):925-36. Epub 2008 May 23 doi: 10.1038/modpathol.2008.49. PMID: 18500270
Increased expression of hypoxia-inducible factor 1alpha in type I and type II endometrial carcinomas.
Pansare V, Munkarah AR, Schimp V, Haitham Arabi M, Saed GM, Morris RT, Ali-Fehmi R
Mod Pathol 2007 Jan;20(1):35-43. Epub 2006 Nov 10 doi: 10.1038/modpathol.3800718. PMID: 17099695

Diagnosis

Quality of life in patients affected by endometrial cancer: comparison among laparotomy, laparoscopy and vaginal approach.
Berretta R, Gizzo S, Noventa M, Marrazzo V, Franchi L, Migliavacca C, Michela M, Merisio C, Modena AB, Patrelli TS
Pathol Oncol Res 2015 Jul;21(3):811-6. Epub 2015 Jan 10 doi: 10.1007/s12253-014-9895-2. PMID: 25573595
Expression of p53 in imprint smears of endometrial carcinoma.
Kosmas K, Stamoulas M, Marouga A, Kavantzas N, Patsouris E, Athanassiadou P
Diagn Cytopathol 2014 May;42(5):416-22. Epub 2013 Oct 25 doi: 10.1002/dc.23056. PMID: 24167025
Expression of Ki-67 as proliferation biomarker in imprint smears of endometrial carcinoma.
Kosmas K, Stamoulas M, Marouga A, Kavantzas N, Patsouris E, Athanassiadou P
Diagn Cytopathol 2013 Mar;41(3):212-7. Epub 2011 Sep 30 doi: 10.1002/dc.21825. PMID: 21965052
Increased expression of hypoxia-inducible factor 1alpha in type I and type II endometrial carcinomas.
Pansare V, Munkarah AR, Schimp V, Haitham Arabi M, Saed GM, Morris RT, Ali-Fehmi R
Mod Pathol 2007 Jan;20(1):35-43. Epub 2006 Nov 10 doi: 10.1038/modpathol.3800718. PMID: 17099695
Endometrial brush cytology of advanced postmenopausal endometrium: does endometrial intraepithelial neoplasia exist in the absence of hyperplasia?
Maksem JA
Diagn Cytopathol 1998 Nov;19(5):338-43. doi: 10.1002/(sici)1097-0339(199811)19:5<338::aid-dc5>3.0.co;2-h. PMID: 9812226

Therapy

Clinicopathological and molecular analysis of endometrial carcinoma associated with tamoxifen.
Turbiner J, Moreno-Bueno G, Dahiya S, Sánchez-Estevez C, Hardisson D, Prat J, Oliva E, Palacios J
Mod Pathol 2008 Aug;21(8):925-36. Epub 2008 May 23 doi: 10.1038/modpathol.2008.49. PMID: 18500270
Identification of a novel estrogen-regulated gene, EIG121, induced by hormone replacement therapy and differentially expressed in type I and type II endometrial cancer.
Deng L, Broaddus RR, McCampbell A, Shipley GL, Loose DS, Stancel GM, Pickar JH, Davies PJ
Clin Cancer Res 2005 Dec 1;11(23):8258-64. doi: 10.1158/1078-0432.CCR-05-1189. PMID: 16322283

Prognosis

Quality of life in patients affected by endometrial cancer: comparison among laparotomy, laparoscopy and vaginal approach.
Berretta R, Gizzo S, Noventa M, Marrazzo V, Franchi L, Migliavacca C, Michela M, Merisio C, Modena AB, Patrelli TS
Pathol Oncol Res 2015 Jul;21(3):811-6. Epub 2015 Jan 10 doi: 10.1007/s12253-014-9895-2. PMID: 25573595
HER-2/neu is an independent prognostic factor in type I endometrial adenocarcinoma.
Kalogiannidis I, Petousis S, Bobos M, Margioula-Siarkou C, Topalidou M, Papanikolaou A, Vergote I, Agorastos T
Arch Gynecol Obstet 2014 Dec;290(6):1231-7. Epub 2014 Jul 15 doi: 10.1007/s00404-014-3333-2. PMID: 25022554
Expression of p53 in imprint smears of endometrial carcinoma.
Kosmas K, Stamoulas M, Marouga A, Kavantzas N, Patsouris E, Athanassiadou P
Diagn Cytopathol 2014 May;42(5):416-22. Epub 2013 Oct 25 doi: 10.1002/dc.23056. PMID: 24167025
Clinicopathological and molecular analysis of endometrial carcinoma associated with tamoxifen.
Turbiner J, Moreno-Bueno G, Dahiya S, Sánchez-Estevez C, Hardisson D, Prat J, Oliva E, Palacios J
Mod Pathol 2008 Aug;21(8):925-36. Epub 2008 May 23 doi: 10.1038/modpathol.2008.49. PMID: 18500270
Increased expression of hypoxia-inducible factor 1alpha in type I and type II endometrial carcinomas.
Pansare V, Munkarah AR, Schimp V, Haitham Arabi M, Saed GM, Morris RT, Ali-Fehmi R
Mod Pathol 2007 Jan;20(1):35-43. Epub 2006 Nov 10 doi: 10.1038/modpathol.3800718. PMID: 17099695

Clinical prediction guides

Increased expression of hypoxia-inducible factor 1alpha in type I and type II endometrial carcinomas.
Pansare V, Munkarah AR, Schimp V, Haitham Arabi M, Saed GM, Morris RT, Ali-Fehmi R
Mod Pathol 2007 Jan;20(1):35-43. Epub 2006 Nov 10 doi: 10.1038/modpathol.3800718. PMID: 17099695

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...