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Soft Tissue Perineurioma

MedGen UID:
277971
•Concept ID:
C1370657
•
Neoplastic Process
Synonym: Soft Tissue Perineurioma (WHO Grades I, II, or III)

Definition

A perineurioma not associated with a nerve, arising from the soft tissues. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSoft Tissue Perineurioma

Professional guidelines

PubMed

Current management of benign retroperitoneal tumors.
Tirotta F, Napolitano A, Noh S, Schmitz E, Nessim C, Patel D, Sicklick JK, Smith M, Thway K, van der Hage J, Ford SJ, Tseng WW
Eur J Surg Oncol 2023 Jun;49(6):1081-1090. Epub 2022 Jul 19 doi: 10.1016/j.ejso.2022.07.006. PMID: 35879135
DIFFERENTIAL DIAGNOSIS OF SOFT TISSUE TUMORS.
Kapustianskyi D, Ivanytskyi I, Ivanytska T, Zhamardiy V, Donchenko V
Wiad Lek 2022;75(6):1596-1599. doi: 10.36740/WLek202206131. PMID: 35907241
The many faces of solitary fibrous tumor; diversity of histological features, differential diagnosis and role of molecular studies and surrogate markers in avoiding misdiagnosis and predicting the behavior.
Tariq MU, Din NU, Abdul-Ghafar J, Park YK
Diagn Pathol 2021 Apr 20;16(1):32. doi: 10.1186/s13000-021-01095-2. PMID: 33879215Free PMC Article

Recent clinical studies

Etiology

Utility of LEF1 to differentiate desmoid fibromatosis from its histologic mimics.
Jobbagy S, Lozano-Calderon S, Mullen JT, Nielsen GP, Hung YP, Chebib I
Virchows Arch 2024 May;484(5):807-813. Epub 2024 Mar 19 doi: 10.1007/s00428-024-03782-z. PMID: 38503969
Diagnostic Pathology of Tumors of Peripheral Nerve.
Belakhoua SM, Rodriguez FJ
Neurosurgery 2021 Feb 16;88(3):443-456. doi: 10.1093/neuros/nyab021. PMID: 33588442Free PMC Article
Fine-needle aspiration of soft tissue perineurioma: A comparative analysis of cytomorphology and immunohistochemistry with benign and malignant mimics.
Yang EJ, Hornick JL, Qian X
Cancer Cytopathol 2016 Sep;124(9):651-8. Epub 2016 May 9 doi: 10.1002/cncy.21725. PMID: 27159449
Loss of chromosome 13 in a case of soft tissue perineurioma.
Mott RT, Goodman BK, Burchette JL, Cummings TJ
Clin Neuropathol 2005 Mar-Apr;24(2):69-76. PMID: 15803806
Reticular perineurioma: a distinctive variant of soft tissue perineurioma.
Graadt van Roggen JF, McMenamin ME, Belchis DA, Nielsen GP, Rosenberg AE, Fletcher CD
Am J Surg Pathol 2001 Apr;25(4):485-93. doi: 10.1097/00000478-200104000-00008. PMID: 11257623

Diagnosis

Pediatric Soft Tissue Perineurioma in the Head and Neck.
Wilson T, Wang S, Bolshom B, Stanisce L, Vimawala S, Ahmad N, Solomon D
Ear Nose Throat J 2024 Nov;103(11):693-695. Epub 2022 Mar 1 doi: 10.1177/01455613221079493. PMID: 35229665
Eyelid-Cheek Junction Soft-Tissue Perineurioma: Case Report and Controversies.
Zhao LD, Jarrar FS, Hussain AA, Hyrcza MD, Harvey JT
Ophthalmic Plast Reconstr Surg 2021 Sep-Oct 01;37(5):e181-e184. doi: 10.1097/IOP.0000000000001986. PMID: 33927170
Diagnostic Pathology of Tumors of Peripheral Nerve.
Belakhoua SM, Rodriguez FJ
Neurosurgery 2021 Feb 16;88(3):443-456. doi: 10.1093/neuros/nyab021. PMID: 33588442Free PMC Article
Soft Tissue Perineurioma in a Child With Neurofibromatosis Type 1: A Case Report and Review of the Literature.
Al-Adnani M
Pediatr Dev Pathol 2017 Sep-Oct;20(5):444-448. Epub 2017 Jan 25 doi: 10.1177/1093526617689895. PMID: 28812461
Soft tissue perineurioma of the tongue: report of a case and review of the literature.
Xiao WL, Xue LF, Xu YX
World J Surg Oncol 2014 Jan 13;12:11. doi: 10.1186/1477-7819-12-11. PMID: 24410763Free PMC Article

Prognosis

Soft tissue perineurioma involving the kidney: a report of two cases with an emphasis on differential diagnosis.
Ma TS, Zhou L, Zhou Q, He XL, Zhao M
Diagn Pathol 2021 Sep 30;16(1):87. doi: 10.1186/s13000-021-01149-5. PMID: 34592995Free PMC Article
Intraosseous intraneural perineurioma derived from the inferior alveolar nerve with an abnormality of chromosome 22 and expression of the BCR-ABL fusion gene: report of a case and review of recent literature.
Kurihara J, Yokoo S, Ichikawa M, Shimizu T, Ogawa M, Seki M
World J Surg Oncol 2018 Sep 13;16(1):189. doi: 10.1186/s12957-018-1481-8. PMID: 30213264Free PMC Article
Fine-needle aspiration of soft tissue perineurioma: A comparative analysis of cytomorphology and immunohistochemistry with benign and malignant mimics.
Yang EJ, Hornick JL, Qian X
Cancer Cytopathol 2016 Sep;124(9):651-8. Epub 2016 May 9 doi: 10.1002/cncy.21725. PMID: 27159449
Soft tissue perineurioma of the tongue: report of a case and review of the literature.
Xiao WL, Xue LF, Xu YX
World J Surg Oncol 2014 Jan 13;12:11. doi: 10.1186/1477-7819-12-11. PMID: 24410763Free PMC Article
Plexiform perineurioma of the lip: a case report and review of literature.
Kawakami F, Hirose T, Kimoto A, Komori T, Itoh T
Pathol Int 2012 Oct;62(10):704-8. doi: 10.1111/j.1440-1827.2012.02857.x. PMID: 23005598

Clinical prediction guides

GAB1::ABL1 fusions define a distinctive soft tissue neoplasm, with variable perineurial differentiation, and a predilection for children and young adults.
Agaimy A, Perret R, Demicco EG, Gross J, Liu YJ, Azmani R, Engelmann C, Schubart C, Seppet J, Stoehr R, Le Loarer F, Dickson BC
Genes Chromosomes Cancer 2023 Aug;62(8):449-459. Epub 2023 Feb 21 doi: 10.1002/gcc.23131. PMID: 36744864
Association of intraneural perineurioma with neurofibromatosis type 2.
Pendleton C, Spinner RJ, Dyck PJB, Mauermann ML, Ladak A, Restrepo CE, Baheti S, Klein CJ
Acta Neurochir (Wien) 2020 Aug;162(8):1891-1897. Epub 2020 Jun 11 doi: 10.1007/s00701-020-04439-x. PMID: 32529330
Recurrent Genomic Alterations in Soft Tissue Perineuriomas.
Carter JM, Wu Y, Blessing MM, Folpe AL, Thorland EC, Spinner RJ, Jentoft ME, Wang C, Baheti S, Niu Z, Mauermann ML, Klein CJ
Am J Surg Pathol 2018 Dec;42(12):1708-1714. doi: 10.1097/PAS.0000000000001169. PMID: 30303818
Intraosseous intraneural perineurioma derived from the inferior alveolar nerve with an abnormality of chromosome 22 and expression of the BCR-ABL fusion gene: report of a case and review of recent literature.
Kurihara J, Yokoo S, Ichikawa M, Shimizu T, Ogawa M, Seki M
World J Surg Oncol 2018 Sep 13;16(1):189. doi: 10.1186/s12957-018-1481-8. PMID: 30213264Free PMC Article
Soft-tissue perineurioma. Evidence for an abnormality of chromosome 22, criteria for diagnosis, and review of the literature.
Giannini C, Scheithauer BW, Jenkins RB, Erlandson RA, Perry A, Borell TJ, Hoda RS, Woodruff JM
Am J Surg Pathol 1997 Feb;21(2):164-73. doi: 10.1097/00000478-199702000-00005. PMID: 9042282

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