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Anal canal squamous cell carcinoma

MedGen UID:
233979
Concept ID:
C1332262
Neoplastic Process
Synonyms: Anal Canal Squamous Cell Carcinoma; anal canal squamous cell carcinoma; squamous cell carcinoma of the anal canal; Squamous cell carcinoma of the anal canal
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
HPO: HP:0030438
Monarch Initiative: MONDO:0004132
Orphanet: ORPHA424019

Definition

A squamous cell carcinoma that originates in the anal canal. [from HPO]

Professional guidelines

PubMed

Ortholan C, Resbeut M, Hannoun-Levi JM, Teissier E, Gerard JP, Ronchin P, Zaccariotto A, Minsat M, Benezery K, François E, Salem N, Ellis S, Azria D, Champetier C, Gross E, Cowen D
Int J Radiat Oncol Biol Phys 2012 Apr 1;82(5):1988-95. Epub 2011 May 11 doi: 10.1016/j.ijrobp.2011.02.010. PMID: 21570207
El-Haddad M, Ahmed RS, Al-Suhaibany A, Al-Hazza M, Al-Sanae N, Al-Jabbar AA, Hamoud S, Ashaary L, Bazerbashy S, Balaraj K
Ann Saudi Med 2011 Mar-Apr;31(2):158-62. doi: 10.4103/0256-4947.77488. PMID: 21403412Free PMC Article
Roohipour R, Patil S, Goodman KA, Minsky BD, Wong WD, Guillem JG, Paty PB, Weiser MR, Neuman HB, Shia J, Schrag D, Temple LK
Dis Colon Rectum 2008 Feb;51(2):147-53. Epub 2008 Jan 8 doi: 10.1007/s10350-007-9125-z. PMID: 18180997

Recent clinical studies

Etiology

Yamada K, Shiraishi K, Takashima A, Takayanagi D, Saiki Y, Takano S, Tanaka M, Fukunaga M, Sugimoto K, Iwasaki Y, Nakamura Y, Kuwahara D, Tsuji Y, Takano M, Sugihara K, Ajioka Y
Int J Clin Oncol 2023 Aug;28(8):990-998. Epub 2023 Apr 28 doi: 10.1007/s10147-023-02339-5. PMID: 37115427
Yamada K, Saiki Y, Komori K, Shiomi A, Ueno M, Ito M, Hida K, Yamamoto S, Shiozawa M, Ishihara S, Kanemitsu Y, Ueno H, Kinjo T, Maeda K, Kawamura J, Fujita F, Takahashi K, Mizushima T, Shimada Y, Sasaki S, Sunami E, Ishida F, Hirata K, Ohnuma S, Funahashi K, Watanabe J, Kinugasa Y, Yamaguchi S, Hashiguchi Y, Ikeda M, Sudo T, Komatsu Y, Koda K, Sakamoto K, Okajima M, Ishida H, Hisamatsu Y, Masuda T, Mori S, Minami K, Hasegawa S, Endo S, Iwashita A, Hamada M, Ajioka Y, Usuku K, Ikeda T, Sugihara K
Cancer Med 2022 Jul;11(14):2735-2743. Epub 2022 Mar 10 doi: 10.1002/cam4.4631. PMID: 35274487Free PMC Article
Das A, Arunsingh M, Bhattacharyya T, Prasath SS, Balakrishnan A, Mallick I
J Cancer Res Ther 2021 Jul-Sep;17(4):975-981. doi: 10.4103/jcrt.JCRT_212_19. PMID: 34528551
Wegner RE, Abel S, Hasan S, White RJ, Raj M, Monga D, Finley G, McCormick J, Kirichenko AV
Am J Clin Oncol 2019 Jun;42(6):519-526. doi: 10.1097/COC.0000000000000551. PMID: 31136369
Wisniewski A, Fléjou JF, Siproudhis L, Abramowitz L, Svrcek M, Beaugerie L
J Crohns Colitis 2017 Aug 1;11(8):1011-1018. doi: 10.1093/ecco-jcc/jjx035. PMID: 28379306

Diagnosis

Yamada K, Shiraishi K, Takashima A, Takayanagi D, Saiki Y, Takano S, Tanaka M, Fukunaga M, Sugimoto K, Iwasaki Y, Nakamura Y, Kuwahara D, Tsuji Y, Takano M, Sugihara K, Ajioka Y
Int J Clin Oncol 2023 Aug;28(8):990-998. Epub 2023 Apr 28 doi: 10.1007/s10147-023-02339-5. PMID: 37115427
Huffman DL, Jayakrishnan TT, Vannatter BL, Monga DK, Finley GG, McCormick JT, Kirichenko AV, Wegner RE
Cancer Treat Res Commun 2021;27:100347. Epub 2021 Mar 5 doi: 10.1016/j.ctarc.2021.100347. PMID: 33711636
Wisniewski A, Fléjou JF, Siproudhis L, Abramowitz L, Svrcek M, Beaugerie L
J Crohns Colitis 2017 Aug 1;11(8):1011-1018. doi: 10.1093/ecco-jcc/jjx035. PMID: 28379306
Lefèvre JH, Corte H, Tiret E, Boccara D, Chaouat M, Touboul E, Svrcek M, Lefrancois M, Shields C, Parc Y
Ann Surg Oncol 2012 Dec;19(13):4186-92. Epub 2012 Jul 24 doi: 10.1245/s10434-012-2485-1. PMID: 22825769
Roohipour R, Patil S, Goodman KA, Minsky BD, Wong WD, Guillem JG, Paty PB, Weiser MR, Neuman HB, Shia J, Schrag D, Temple LK
Dis Colon Rectum 2008 Feb;51(2):147-53. Epub 2008 Jan 8 doi: 10.1007/s10350-007-9125-z. PMID: 18180997

Therapy

Cattaneo CG, Musio D, Tanzi F, Guidi G, Palaia I, Tombolini V, DE Felice F
In Vivo 2022 Sep-Oct;36(5):2521-2524. doi: 10.21873/invivo.12988. PMID: 36099119Free PMC Article
Xiao W, Yuan Y, Wang S, Liao Z, Cai P, Chen B, Zhang R, Wang F, Zeng Z, Gao Y
Front Immunol 2021;12:798451. Epub 2022 Jan 14 doi: 10.3389/fimmu.2021.798451. PMID: 35095878Free PMC Article
Huffman DL, Jayakrishnan TT, Vannatter BL, Monga DK, Finley GG, McCormick JT, Kirichenko AV, Wegner RE
Cancer Treat Res Commun 2021;27:100347. Epub 2021 Mar 5 doi: 10.1016/j.ctarc.2021.100347. PMID: 33711636
Lefèvre JH, Corte H, Tiret E, Boccara D, Chaouat M, Touboul E, Svrcek M, Lefrancois M, Shields C, Parc Y
Ann Surg Oncol 2012 Dec;19(13):4186-92. Epub 2012 Jul 24 doi: 10.1245/s10434-012-2485-1. PMID: 22825769
Leroy J, Jamali F, Forbes L, Smith M, Rubino F, Mutter D, Marescaux J
Surg Endosc 2004 Feb;18(2):281-9. Epub 2003 Dec 29 doi: 10.1007/s00464-002-8877-8. PMID: 14691716

Prognosis

Yamada K, Shiraishi K, Takashima A, Takayanagi D, Saiki Y, Takano S, Tanaka M, Fukunaga M, Sugimoto K, Iwasaki Y, Nakamura Y, Kuwahara D, Tsuji Y, Takano M, Sugihara K, Ajioka Y
Int J Clin Oncol 2023 Aug;28(8):990-998. Epub 2023 Apr 28 doi: 10.1007/s10147-023-02339-5. PMID: 37115427
Yamada K, Saiki Y, Komori K, Shiomi A, Ueno M, Ito M, Hida K, Yamamoto S, Shiozawa M, Ishihara S, Kanemitsu Y, Ueno H, Kinjo T, Maeda K, Kawamura J, Fujita F, Takahashi K, Mizushima T, Shimada Y, Sasaki S, Sunami E, Ishida F, Hirata K, Ohnuma S, Funahashi K, Watanabe J, Kinugasa Y, Yamaguchi S, Hashiguchi Y, Ikeda M, Sudo T, Komatsu Y, Koda K, Sakamoto K, Okajima M, Ishida H, Hisamatsu Y, Masuda T, Mori S, Minami K, Hasegawa S, Endo S, Iwashita A, Hamada M, Ajioka Y, Usuku K, Ikeda T, Sugihara K
Cancer Med 2022 Jul;11(14):2735-2743. Epub 2022 Mar 10 doi: 10.1002/cam4.4631. PMID: 35274487Free PMC Article
Das A, Arunsingh M, Bhattacharyya T, Prasath SS, Balakrishnan A, Mallick I
J Cancer Res Ther 2021 Jul-Sep;17(4):975-981. doi: 10.4103/jcrt.JCRT_212_19. PMID: 34528551
Wegner RE, Abel S, Hasan S, White RJ, Raj M, Monga D, Finley G, McCormick J, Kirichenko AV
Am J Clin Oncol 2019 Jun;42(6):519-526. doi: 10.1097/COC.0000000000000551. PMID: 31136369
Wisniewski A, Fléjou JF, Siproudhis L, Abramowitz L, Svrcek M, Beaugerie L
J Crohns Colitis 2017 Aug 1;11(8):1011-1018. doi: 10.1093/ecco-jcc/jjx035. PMID: 28379306

Clinical prediction guides

Huffman DL, Jayakrishnan TT, Vannatter BL, Monga DK, Finley GG, McCormick JT, Kirichenko AV, Wegner RE
Cancer Treat Res Commun 2021;27:100347. Epub 2021 Mar 5 doi: 10.1016/j.ctarc.2021.100347. PMID: 33711636
Shaw RD, Eid MA, Milanese ED, Ivatury SJ
Colorectal Dis 2021 Jun;23(6):1480-1486. Epub 2021 Mar 12 doi: 10.1111/codi.15590. PMID: 33599113
Wegner RE, Abel S, Hasan S, White RJ, Raj M, Monga D, Finley G, McCormick J, Kirichenko AV
Am J Clin Oncol 2019 Jun;42(6):519-526. doi: 10.1097/COC.0000000000000551. PMID: 31136369
El-Haddad M, Ahmed RS, Al-Suhaibany A, Al-Hazza M, Al-Sanae N, Al-Jabbar AA, Hamoud S, Ashaary L, Bazerbashy S, Balaraj K
Ann Saudi Med 2011 Mar-Apr;31(2):158-62. doi: 10.4103/0256-4947.77488. PMID: 21403412Free PMC Article
Roohipour R, Patil S, Goodman KA, Minsky BD, Wong WD, Guillem JG, Paty PB, Weiser MR, Neuman HB, Shia J, Schrag D, Temple LK
Dis Colon Rectum 2008 Feb;51(2):147-53. Epub 2008 Jan 8 doi: 10.1007/s10350-007-9125-z. PMID: 18180997

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