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Growth failure

MedGen UID:
163904
•Concept ID:
C0878787
•
Disease or Syndrome
Synonym: Growth Failure

Definition

Less than normal linear growth in an infant or child. [from NCI]

Professional guidelines

PubMed

Diagnosis and management of Silver-Russell syndrome: first international consensus statement.
Wakeling EL, Brioude F, Lokulo-Sodipe O, O'Connell SM, Salem J, Bliek J, Canton AP, Chrzanowska KH, Davies JH, Dias RP, Dubern B, Elbracht M, Giabicani E, Grimberg A, Grønskov K, Hokken-Koelega AC, Jorge AA, Kagami M, Linglart A, Maghnie M, Mohnike K, Monk D, Moore GE, Murray PG, Ogata T, Petit IO, Russo S, Said E, Toumba M, Tümer Z, Binder G, Eggermann T, Harbison MD, Temple IK, Mackay DJ, Netchine I
Nat Rev Endocrinol 2017 Feb;13(2):105-124. Epub 2016 Sep 2 doi: 10.1038/nrendo.2016.138. PMID: 27585961
Guidelines for Growth Hormone and Insulin-Like Growth Factor-I Treatment in Children and Adolescents: Growth Hormone Deficiency, Idiopathic Short Stature, and Primary Insulin-Like Growth Factor-I Deficiency.
Grimberg A, DiVall SA, Polychronakos C, Allen DB, Cohen LE, Quintos JB, Rossi WC, Feudtner C, Murad MH; Drug and Therapeutics Committee and Ethics Committee of the Pediatric Endocrine Society
Horm Res Paediatr 2016;86(6):361-397. Epub 2016 Nov 25 doi: 10.1159/000452150. PMID: 27884013
Non-cirrhotic portal hypertension - diagnosis and management.
Khanna R, Sarin SK
J Hepatol 2014 Feb;60(2):421-41. Epub 2013 Aug 23 doi: 10.1016/j.jhep.2013.08.013. PMID: 23978714

Recent clinical studies

Etiology

Special Populations-Surgical Infants.
Riddle S, Karpen H
Clin Perinatol 2023 Sep;50(3):715-728. Epub 2023 Jun 23 doi: 10.1016/j.clp.2023.04.008. PMID: 37536774
Feeding Interventions for Infants with Growth Failure in the First Six Months of Life: A Systematic Review.
Rana R, McGrath M, Gupta P, Thakur E, Kerac M
Nutrients 2020 Jul 9;12(7) doi: 10.3390/nu12072044. PMID: 32660020Free PMC Article
Adolescent Undernutrition: Global Burden, Physiology, and Nutritional Risks.
Christian P, Smith ER
Ann Nutr Metab 2018;72(4):316-328. Epub 2018 May 4 doi: 10.1159/000488865. PMID: 29730657
Childhood stunting: a global perspective.
de Onis M, Branca F
Matern Child Nutr 2016 May;12 Suppl 1(Suppl 1):12-26. doi: 10.1111/mcn.12231. PMID: 27187907Free PMC Article
Cachexia: a new definition.
Evans WJ, Morley JE, Argilés J, Bales C, Baracos V, Guttridge D, Jatoi A, Kalantar-Zadeh K, Lochs H, Mantovani G, Marks D, Mitch WE, Muscaritoli M, Najand A, Ponikowski P, Rossi Fanelli F, Schambelan M, Schols A, Schuster M, Thomas D, Wolfe R, Anker SD
Clin Nutr 2008 Dec;27(6):793-9. Epub 2008 Aug 21 doi: 10.1016/j.clnu.2008.06.013. PMID: 18718696

Diagnosis

Common sleep disorders in children: assessment and treatment.
Thabet F, Tabarki B
Neurosciences (Riyadh) 2023 Apr;28(2):85-90. doi: 10.17712/nsj.2023.2.20220111. PMID: 37045460Free PMC Article
Evaluation of Short Stature in Children and Adolescents.
Patel R, Bajpai A
Indian J Pediatr 2021 Dec;88(12):1196-1202. Epub 2021 Aug 16 doi: 10.1007/s12098-021-03880-9. PMID: 34398416
Growth hormone deficiency and replacement in children.
Boguszewski MCS
Rev Endocr Metab Disord 2021 Mar;22(1):101-108. Epub 2020 Oct 8 doi: 10.1007/s11154-020-09604-2. PMID: 33029711
Adolescent Undernutrition: Global Burden, Physiology, and Nutritional Risks.
Christian P, Smith ER
Ann Nutr Metab 2018;72(4):316-328. Epub 2018 May 4 doi: 10.1159/000488865. PMID: 29730657
Cachexia: a new definition.
Evans WJ, Morley JE, Argilés J, Bales C, Baracos V, Guttridge D, Jatoi A, Kalantar-Zadeh K, Lochs H, Mantovani G, Marks D, Mitch WE, Muscaritoli M, Najand A, Ponikowski P, Rossi Fanelli F, Schambelan M, Schols A, Schuster M, Thomas D, Wolfe R, Anker SD
Clin Nutr 2008 Dec;27(6):793-9. Epub 2008 Aug 21 doi: 10.1016/j.clnu.2008.06.013. PMID: 18718696

Therapy

Somatrogon: First Approval.
Lamb YN
Drugs 2022 Feb;82(2):227-234. doi: 10.1007/s40265-021-01663-2. PMID: 35041176
Clinical practice recommendations for growth hormone treatment in children with chronic kidney disease.
Drube J, Wan M, Bonthuis M, Wühl E, Bacchetta J, Santos F, Grenda R, Edefonti A, Harambat J, Shroff R, Tönshoff B, Haffner D; European Society for Paediatric Nephrology Chronic Kidney Disease Mineral and Bone Disorders, Dialysis, and Transplantation Working Groups
Nat Rev Nephrol 2019 Sep;15(9):577-589. Epub 2019 Jun 13 doi: 10.1038/s41581-019-0161-4. PMID: 31197263Free PMC Article
Update on Postnatal Steroids.
Halliday HL
Neonatology 2017;111(4):415-422. Epub 2017 May 25 doi: 10.1159/000458460. PMID: 28538237
Growth and growth hormone: An overview.
Teran E, Chesner J, Rapaport R
Growth Horm IGF Res 2016 Jun;28:3-5. Epub 2016 Feb 23 doi: 10.1016/j.ghir.2016.02.004. PMID: 26936284
Mecasermin.
Keating GM
BioDrugs 2008;22(3):177-88. doi: 10.2165/00063030-200822030-00004. PMID: 18481900

Prognosis

Global burden of 87 risk factors in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.
GBD 2019 Risk Factors Collaborators
Lancet 2020 Oct 17;396(10258):1223-1249. doi: 10.1016/S0140-6736(20)30752-2. PMID: 33069327Free PMC Article
Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.
GBD 2016 Risk Factors Collaborators
Lancet 2017 Sep 16;390(10100):1345-1422. doi: 10.1016/S0140-6736(17)32366-8. PMID: 28919119Free PMC Article
Malignant Infantile Osteopetrosis.
Gillani S, Abbas Z
J Ayub Med Coll Abbottabad 2017 Apr-Jun;29(2):350-352. PMID: 28718264
Genetics of Short Stature.
Jee YH, Andrade AC, Baron J, Nilsson O
Endocrinol Metab Clin North Am 2017 Jun;46(2):259-281. Epub 2017 Feb 23 doi: 10.1016/j.ecl.2017.01.001. PMID: 28476223Free PMC Article
Every Newborn: progress, priorities, and potential beyond survival.
Lawn JE, Blencowe H, Oza S, You D, Lee AC, Waiswa P, Lalli M, Bhutta Z, Barros AJ, Christian P, Mathers C, Cousens SN; Lancet Every Newborn Study Group
Lancet 2014 Jul 12;384(9938):189-205. Epub 2014 May 19 doi: 10.1016/S0140-6736(14)60496-7. PMID: 24853593

Clinical prediction guides

Neonatal and Preterm Infant Growth Assessment.
Fenton TR, Dai S, Lalari V, Alshaikh B
Clin Perinatol 2022 Jun;49(2):295-311. doi: 10.1016/j.clp.2022.02.001. PMID: 35659088
Evaluation of Short Stature in Children and Adolescents.
Patel R, Bajpai A
Indian J Pediatr 2021 Dec;88(12):1196-1202. Epub 2021 Aug 16 doi: 10.1007/s12098-021-03880-9. PMID: 34398416
Diagnosing Pediatric Malnutrition.
Bouma S
Nutr Clin Pract 2017 Feb;32(1):52-67. Epub 2016 Oct 23 doi: 10.1177/0884533616671861. PMID: 27765878
Childhood stunting: a global perspective.
de Onis M, Branca F
Matern Child Nutr 2016 May;12 Suppl 1(Suppl 1):12-26. doi: 10.1111/mcn.12231. PMID: 27187907Free PMC Article
Mecasermin.
Keating GM
BioDrugs 2008;22(3):177-88. doi: 10.2165/00063030-200822030-00004. PMID: 18481900

Recent systematic reviews

Higher versus lower sodium intake for preterm infants.
Diller N, Osborn DA, Birch P
Cochrane Database Syst Rev 2023 Oct 12;10(10):CD012642. doi: 10.1002/14651858.CD012642.pub2. PMID: 37824273Free PMC Article
Clinical features, epidemiology, and treatment of Shwachman-Diamond syndrome: a systematic review.
Han X, Lu S, Gu C, Bian Z, Xie X, Qiao X
BMC Pediatr 2023 Oct 6;23(1):503. doi: 10.1186/s12887-023-04324-3. PMID: 37803383Free PMC Article
Zinc supplementation for preventing mortality, morbidity, and growth failure in children aged 6 months to 12 years.
Imdad A, Rogner J, Sherwani RN, Sidhu J, Regan A, Haykal MR, Tsistinas O, Smith A, Chan XHS, Mayo-Wilson E, Bhutta ZA
Cochrane Database Syst Rev 2023 Mar 30;3(3):CD009384. doi: 10.1002/14651858.CD009384.pub3. PMID: 36994923Free PMC Article
Feeding Interventions for Infants with Growth Failure in the First Six Months of Life: A Systematic Review.
Rana R, McGrath M, Gupta P, Thakur E, Kerac M
Nutrients 2020 Jul 9;12(7) doi: 10.3390/nu12072044. PMID: 32660020Free PMC Article
Preterm Infant Growth Velocity Calculations: A Systematic Review.
Fenton TR, Chan HT, Madhu A, Griffin IJ, Hoyos A, Ziegler EE, Groh-Wargo S, Carlson SJ, Senterre T, Anderson D, Ehrenkranz RA
Pediatrics 2017 Mar;139(3) doi: 10.1542/peds.2016-2045. PMID: 28246339

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