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Cellular schwannoma

MedGen UID:
98124
Concept ID:
C0431124
Neoplastic Process
Synonyms: Cellular neurilemmoma; Cellular Neurilemmoma; cellular neurilemmoma; Cellular Neurinoma; cellular neurinoma; Cellular Schwannoma; cellular schwannoma; CSCHW
SNOMED CT: Cellular neurilemmoma (404026003); Cellular schwannoma (404026003); Cellular neurilemmoma (253086004); Cellular schwannoma (253086004)
 
Monarch Initiative: MONDO:0002548

Definition

A morphologic variant of schwannoma characterized by hypercellularity, Antoni A pattern, and the absence of well-formed Verocay bodies. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCellular schwannoma

Professional guidelines

PubMed

Koza SA, Tabet AC, Bonaglia MC, Andres S, Anderlid BM, Aten E, Stiefsohn D; European Phelan-McDermid syndrome consortium, Evans DG, van Ravenswaaij-Arts CMA, Kant SG
Eur J Med Genet 2023 Jul;66(7):104773. Epub 2023 Apr 28 doi: 10.1016/j.ejmg.2023.104773. PMID: 37120077
Magro G
Surg Pathol Clin 2018 Mar;11(1):91-121. Epub 2017 Dec 9 doi: 10.1016/j.path.2017.09.005. PMID: 29413661
Halliday J, Rutherford SA, McCabe MG, Evans DG
Expert Rev Neurother 2018 Jan;18(1):29-39. Epub 2017 Nov 7 doi: 10.1080/14737175.2018.1399795. PMID: 29088993

Recent clinical studies

Etiology

Jia Q, Lou Y, Chen D, Li X, Liu Y, Chu R, Wang T, Zhou Z, Li D, Wan W, Huang Q, Yang X, Wang T, Wu Z, Xiao J
Spine J 2024 May;24(5):858-866. Epub 2024 Jan 23 doi: 10.1016/j.spinee.2024.01.006. PMID: 38272127
Shapira Y, Juniat V, Dave T, Hussain A, McNeely D, Watanabe A, Yoneda A, Saeed P, Woo KI, Hardy TG, Price B, Drummond K, Selva D
Eye (Lond) 2023 Jan;37(1):48-53. Epub 2022 Jan 9 doi: 10.1038/s41433-021-01850-1. PMID: 34999720Free PMC Article
Zhang Z, Zheng X, Zhang D, Zhang J, Li F, Li C, Wang X, Li J, Han D, Zhang J
World Neurosurg 2022 Feb;158:e166-e178. Epub 2021 Oct 26 doi: 10.1016/j.wneu.2021.10.145. PMID: 34710579
Zhu J, Yang Z, Tang R, Tang G
Eur J Radiol 2021 Aug;141:109783. Epub 2021 May 21 doi: 10.1016/j.ejrad.2021.109783. PMID: 34049057
Zhang E, Zhang J, Lang N, Yuan H
Eur J Radiol 2018 Aug;105:81-86. Epub 2018 May 30 doi: 10.1016/j.ejrad.2018.05.025. PMID: 30017303

Diagnosis

Shapira Y, Juniat V, Dave T, Hussain A, McNeely D, Watanabe A, Yoneda A, Saeed P, Woo KI, Hardy TG, Price B, Drummond K, Selva D
Eye (Lond) 2023 Jan;37(1):48-53. Epub 2022 Jan 9 doi: 10.1038/s41433-021-01850-1. PMID: 34999720Free PMC Article
Coy S, Rashid R, Stemmer-Rachamimov A, Santagata S
Acta Neuropathol 2020 Apr;139(4):643-665. Epub 2019 Jun 4 doi: 10.1007/s00401-019-02029-5. PMID: 31161239Free PMC Article
Zhang E, Zhang J, Lang N, Yuan H
Eur J Radiol 2018 Aug;105:81-86. Epub 2018 May 30 doi: 10.1016/j.ejrad.2018.05.025. PMID: 30017303
Domen H, Iwashiro N, Kimura N, Jinushi E, Komuro K, Ohara M, Ishizaka M
Ann Thorac Surg 2010 Oct;90(4):1352-5. doi: 10.1016/j.athoracsur.2010.04.023. PMID: 20868846
Kurtkaya-Yapicier O, Scheithauer B, Woodruff JM
Histol Histopathol 2003 Jul;18(3):925-34. doi: 10.14670/HH-18.925. PMID: 12792904

Therapy

J Neurosurg Spine 2017 Apr;26(4):494-500. Epub 2017 Jan 13 doi: 10.3171/2016.9.SPINE16778. PMID: 28084933
Ayberk G, Ozveren MF, Yildirim T, Ercan K, Cay EK, Koçak A
Turk Neurosurg 2008 Oct;18(4):366-73. PMID: 19107682
Koyye RT, Mahadevan A, Santosh V, Chickabasaviah YT, Govindappa SS, Hegde T, Shankar SK
Brain Tumor Pathol 2003;20(2):79-83. doi: 10.1007/BF02483451. PMID: 14756445

Prognosis

Jia Q, Lou Y, Chen D, Li X, Liu Y, Chu R, Wang T, Zhou Z, Li D, Wan W, Huang Q, Yang X, Wang T, Wu Z, Xiao J
Spine J 2024 May;24(5):858-866. Epub 2024 Jan 23 doi: 10.1016/j.spinee.2024.01.006. PMID: 38272127
Zhu J, Yang Z, Tang R, Tang G
Eur J Radiol 2021 Aug;141:109783. Epub 2021 May 21 doi: 10.1016/j.ejrad.2021.109783. PMID: 34049057
Coy S, Rashid R, Stemmer-Rachamimov A, Santagata S
Acta Neuropathol 2020 Apr;139(4):643-665. Epub 2019 Jun 4 doi: 10.1007/s00401-019-02029-5. PMID: 31161239Free PMC Article
Zhang E, Zhang J, Lang N, Yuan H
Eur J Radiol 2018 Aug;105:81-86. Epub 2018 May 30 doi: 10.1016/j.ejrad.2018.05.025. PMID: 30017303
Kurtkaya-Yapicier O, Scheithauer B, Woodruff JM
Histol Histopathol 2003 Jul;18(3):925-34. doi: 10.14670/HH-18.925. PMID: 12792904

Clinical prediction guides

Shapira Y, Juniat V, Dave T, Hussain A, McNeely D, Watanabe A, Yoneda A, Saeed P, Woo KI, Hardy TG, Price B, Drummond K, Selva D
Eye (Lond) 2023 Jan;37(1):48-53. Epub 2022 Jan 9 doi: 10.1038/s41433-021-01850-1. PMID: 34999720Free PMC Article
Thompson LDR, Koh SS, Lau SK
Head Neck Pathol 2020 Sep;14(3):571-576. Epub 2019 Sep 4 doi: 10.1007/s12105-019-01071-9. PMID: 31485983Free PMC Article
Jo VY, Mariño-Enríquez A, Fletcher CDM, Hornick JL
Am J Surg Pathol 2018 Oct;42(10):1275-1285. doi: 10.1097/PAS.0000000000001092. PMID: 29863547
Pekmezci M, Reuss DE, Hirbe AC, Dahiya S, Gutmann DH, von Deimling A, Horvai AE, Perry A
Mod Pathol 2015 Feb;28(2):187-200. Epub 2014 Sep 5 doi: 10.1038/modpathol.2014.109. PMID: 25189642Free PMC Article
Casadei GP, Scheithauer BW, Hirose T, Manfrini M, Van Houton C, Wood MB
Cancer 1995 Mar 1;75(5):1109-19. doi: 10.1002/1097-0142(19950301)75:5<1109::aid-cncr2820750510>3.0.co;2-m. PMID: 7850709

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