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Malignant conjunctival melanoma

MedGen UID:
138060
•Concept ID:
C0346360
•
Neoplastic Process
Synonyms: CM; Conjunctiva Melanoma; conjunctiva melanoma; conjunctiva melanoma (disease); conjunctival malignant melanoma; Conjunctival malignant melanoma; Conjunctival Melanoma; conjunctival melanoma; Conjunctival melanoma; Malignant Conjunctiva Melanoma; malignant conjunctiva melanoma; Malignant Conjunctival Melanoma; malignant conjunctival melanoma; Malignant melanoma of conjunctiva; Malignant Melanoma of Conjunctiva; malignant melanoma of conjunctiva; Malignant Melanoma of the Conjunctiva; malignant melanoma of the conjunctiva; melanoma (disease) of conjunctiva; Melanoma of Conjunctiva; melanoma of conjunctiva; Melanoma of the Conjunctiva; melanoma of the conjunctiva
SNOMED CT: Malignant melanoma of conjunctiva (255004001)
 
Monarch Initiative: MONDO:0002096
Orphanet: ORPHA617910

Definition

A melanoma that arises from the conjunctiva. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant conjunctival melanoma

Professional guidelines

PubMed

Conjunctival malignant melanoma in Denmark: epidemiology, treatment and prognosis with special emphasis on tumorigenesis and genetic profile.
Larsen AC
Acta Ophthalmol 2016 May;94 Thesis 1:1-27. doi: 10.1111/aos.13100. PMID: 27192168
Management of pigmented conjunctival lesions.
Oellers P, Karp CL
Ocul Surf 2012 Oct;10(4):251-63. Epub 2012 Aug 11 doi: 10.1016/j.jtos.2012.08.002. PMID: 23084146
Orbital exenteration in 95 cases of primary conjunctival malignant melanoma.
Paridaens AD, McCartney AC, Minassian DC, Hungerford JL
Br J Ophthalmol 1994 Jul;78(7):520-8. doi: 10.1136/bjo.78.7.520. PMID: 7522545Free PMC Article

Recent clinical studies

Etiology

Prognostic factors and survival for malignant conjunctival melanoma and squamous cell carcinoma over four decades.
Abt NB, Zhao J, Huang Y, Eghrari AO
Am J Otolaryngol 2019 Jul-Aug;40(4):577-582. Epub 2019 May 15 doi: 10.1016/j.amjoto.2019.05.013. PMID: 31109806
Gallbladder Metastasis From Conjunctival Melanoma.
Cassou-Mounat T, Luporsi M, Huchet V, Jehanno N
Clin Nucl Med 2019 Feb;44(2):e107-e109. doi: 10.1097/RLU.0000000000002413. PMID: 30516663
Metastatic pattern and survival in disseminated conjunctival melanoma: implications for sentinel lymph node biopsy.
Tuomaala S, Kivelä T
Ophthalmology 2004 Apr;111(4):816-21. doi: 10.1016/j.ophtha.2003.11.001. PMID: 15051218
Corneally displaced malignant conjunctival melanomas.
Tuomaala S, Aine E, Saari KM, Kivelä T
Ophthalmology 2002 May;109(5):914-9. doi: 10.1016/s0161-6420(02)00967-3. PMID: 11986097

Diagnosis

Prognostic factors and survival for malignant conjunctival melanoma and squamous cell carcinoma over four decades.
Abt NB, Zhao J, Huang Y, Eghrari AO
Am J Otolaryngol 2019 Jul-Aug;40(4):577-582. Epub 2019 May 15 doi: 10.1016/j.amjoto.2019.05.013. PMID: 31109806
Conjunctival Melanoma Metastasis to the Contralateral Orbit.
He F, Wang Y, Jia R
J Craniofac Surg 2018 Nov;29(8):2128-2130. doi: 10.1097/SCS.0000000000004673. PMID: 29894459
Amelanotic corneally displaced malignant conjunctival melanoma: a case report evaluated with impression cytology.
Barros Jde N, Motono M, Costa FD, Cunha MC, Chojniak MM
Arq Bras Oftalmol 2014 Jan-Feb;77(1):57-9. doi: 10.5935/0004-2749.20140015. PMID: 25076376
Metastatic pattern and survival in disseminated conjunctival melanoma: implications for sentinel lymph node biopsy.
Tuomaala S, Kivelä T
Ophthalmology 2004 Apr;111(4):816-21. doi: 10.1016/j.ophtha.2003.11.001. PMID: 15051218
Population-based assessment of clinical characteristics predicting outcome of conjunctival melanoma in whites.
Tuomaala S, Eskelin S, Tarkkanen A, Kivelä T
Invest Ophthalmol Vis Sci 2002 Nov;43(11):3399-408. PMID: 12407149

Prognosis

Prognostic factors and survival for malignant conjunctival melanoma and squamous cell carcinoma over four decades.
Abt NB, Zhao J, Huang Y, Eghrari AO
Am J Otolaryngol 2019 Jul-Aug;40(4):577-582. Epub 2019 May 15 doi: 10.1016/j.amjoto.2019.05.013. PMID: 31109806
Metastatic pattern and survival in disseminated conjunctival melanoma: implications for sentinel lymph node biopsy.
Tuomaala S, Kivelä T
Ophthalmology 2004 Apr;111(4):816-21. doi: 10.1016/j.ophtha.2003.11.001. PMID: 15051218
Population-based assessment of clinical characteristics predicting outcome of conjunctival melanoma in whites.
Tuomaala S, Eskelin S, Tarkkanen A, Kivelä T
Invest Ophthalmol Vis Sci 2002 Nov;43(11):3399-408. PMID: 12407149

Clinical prediction guides

Prognostic factors and survival for malignant conjunctival melanoma and squamous cell carcinoma over four decades.
Abt NB, Zhao J, Huang Y, Eghrari AO
Am J Otolaryngol 2019 Jul-Aug;40(4):577-582. Epub 2019 May 15 doi: 10.1016/j.amjoto.2019.05.013. PMID: 31109806
Excision with corneoscleral lamellar keratoplasty and amniotic membrane transplantation of a corneal displaced recurrent conjunctival melanoma.
Kim EC, Kim MS, Kang NY
Korean J Ophthalmol 2012 Oct;26(5):383-7. Epub 2012 Sep 24 doi: 10.3341/kjo.2012.26.5.383. PMID: 23060726Free PMC Article
Population-based assessment of clinical characteristics predicting outcome of conjunctival melanoma in whites.
Tuomaala S, Eskelin S, Tarkkanen A, Kivelä T
Invest Ophthalmol Vis Sci 2002 Nov;43(11):3399-408. PMID: 12407149
Corneally displaced malignant conjunctival melanomas.
Tuomaala S, Aine E, Saari KM, Kivelä T
Ophthalmology 2002 May;109(5):914-9. doi: 10.1016/s0161-6420(02)00967-3. PMID: 11986097
Steroids and neuroendocrine hormones detected by the immunoperoxidase technique from malignant melanomas and nevi of the choroid and conjunctiva.
Di Tondo U, Balestrazzi E, Santeusanio G, Pintucci S, Spadea L
Ophthalmologica 1986;192(1):34-8. doi: 10.1159/000309609. PMID: 3010209

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