U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Fibrocystic change, proliferative type with atypia

MedGen UID:
137716
•Concept ID:
C0334056
•
Disease or Syndrome
Synonyms: Breast Fibrocystic Change, Proliferative Type with Atypia; Fibrocystic Disease, Proliferative Type with Atypia
SNOMED CT: Fibrocystic change, proliferative type with atypia (35813005)

Definition

Breast fibrocystic change characterized by the presence of epithelial cell hyperplasia. Epithelial atypia is present. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFibrocystic change, proliferative type with atypia

Professional guidelines

PubMed

Management of radial sclerosing lesions of the breast diagnosed using percutaneous vacuum-assisted core needle biopsy: recommendations for excision based on seven years' of experience at a single institution.
Resetkova E, Edelweiss M, Albarracin CT, Yang WT
Breast Cancer Res Treat 2011 Jun;127(2):335-43. Epub 2008 Jul 15 doi: 10.1007/s10549-008-0119-x. PMID: 18626769

Recent clinical studies

Etiology

Mucocele-like lesions of the breast: a clinical outcome and histologic analysis of 102 cases.
Meares AL, Frank RD, Degnim AC, Vierkant RA, Frost MH, Hartmann LC, Winham SJ, Visscher DW
Hum Pathol 2016 Mar;49:33-8. Epub 2015 Oct 31 doi: 10.1016/j.humpath.2015.10.004. PMID: 26826407Free PMC Article
Age and associated fibrocystic changes are prognostically significant in patients with small node-negative (T1a,bN0) invasive breast cancer.
Durak MG, Gonzalez-Angulo AM, Hanrahan EO, Broglio KR, Valero V, Hortobagyi GN, Hunt KK, Sahin AA
Breast J 2011 Sep-Oct;17(5):462-9. Epub 2011 Jul 5 doi: 10.1111/j.1524-4741.2011.01116.x. PMID: 21726347
Management of radial sclerosing lesions of the breast diagnosed using percutaneous vacuum-assisted core needle biopsy: recommendations for excision based on seven years' of experience at a single institution.
Resetkova E, Edelweiss M, Albarracin CT, Yang WT
Breast Cancer Res Treat 2011 Jun;127(2):335-43. Epub 2008 Jul 15 doi: 10.1007/s10549-008-0119-x. PMID: 18626769

Diagnosis

Mucocele-like lesions of the breast: a clinical outcome and histologic analysis of 102 cases.
Meares AL, Frank RD, Degnim AC, Vierkant RA, Frost MH, Hartmann LC, Winham SJ, Visscher DW
Hum Pathol 2016 Mar;49:33-8. Epub 2015 Oct 31 doi: 10.1016/j.humpath.2015.10.004. PMID: 26826407Free PMC Article
Age and associated fibrocystic changes are prognostically significant in patients with small node-negative (T1a,bN0) invasive breast cancer.
Durak MG, Gonzalez-Angulo AM, Hanrahan EO, Broglio KR, Valero V, Hortobagyi GN, Hunt KK, Sahin AA
Breast J 2011 Sep-Oct;17(5):462-9. Epub 2011 Jul 5 doi: 10.1111/j.1524-4741.2011.01116.x. PMID: 21726347
Management of radial sclerosing lesions of the breast diagnosed using percutaneous vacuum-assisted core needle biopsy: recommendations for excision based on seven years' of experience at a single institution.
Resetkova E, Edelweiss M, Albarracin CT, Yang WT
Breast Cancer Res Treat 2011 Jun;127(2):335-43. Epub 2008 Jul 15 doi: 10.1007/s10549-008-0119-x. PMID: 18626769

Prognosis

Mucocele-like lesions of the breast: a clinical outcome and histologic analysis of 102 cases.
Meares AL, Frank RD, Degnim AC, Vierkant RA, Frost MH, Hartmann LC, Winham SJ, Visscher DW
Hum Pathol 2016 Mar;49:33-8. Epub 2015 Oct 31 doi: 10.1016/j.humpath.2015.10.004. PMID: 26826407Free PMC Article
Age and associated fibrocystic changes are prognostically significant in patients with small node-negative (T1a,bN0) invasive breast cancer.
Durak MG, Gonzalez-Angulo AM, Hanrahan EO, Broglio KR, Valero V, Hortobagyi GN, Hunt KK, Sahin AA
Breast J 2011 Sep-Oct;17(5):462-9. Epub 2011 Jul 5 doi: 10.1111/j.1524-4741.2011.01116.x. PMID: 21726347

Clinical prediction guides

Age and associated fibrocystic changes are prognostically significant in patients with small node-negative (T1a,bN0) invasive breast cancer.
Durak MG, Gonzalez-Angulo AM, Hanrahan EO, Broglio KR, Valero V, Hortobagyi GN, Hunt KK, Sahin AA
Breast J 2011 Sep-Oct;17(5):462-9. Epub 2011 Jul 5 doi: 10.1111/j.1524-4741.2011.01116.x. PMID: 21726347

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...