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Breast fibrocystic disease

MedGen UID:
42015
•Concept ID:
C0016034
•
Disease or Syndrome
Synonyms: Breast Disease, Fibrocystic; Breast Dysplasia; Breast Fibrocystic Change; Breast Fibrocystic Changes; Breast Fibrocystic Disease; Disease, Fibrocystic Breast; Dysplasia, Breast; Dysplasia, Mammary; Fibrocystic Breast Disease; Fibrocystic Changes of Breast; Fibrocystic Disease of Breast; Fibrocystic Mastopathy; Mammary Dysplasia; Mastopathy, Fibrocystic
SNOMED CT: Schimmelbusch's disease (27431007); Fibrocystic breast changes (27431007); Fibrocystic mastopathy (27431007); Fibrocystic change of breast (27431007); Fibrocystic disease of breast (27431007); Diffuse cystic mastopathy (27431007); Gross cystic disease of breast (27431007)
 
Monarch Initiative: MONDO:0005219

Definition

Fibrosis associated with cyst formation in the breast parenchyma. [from NCI]

Professional guidelines

PubMed

Mastalgia: a review of management.
Olawaiye A, Withiam-Leitch M, Danakas G, Kahn K
J Reprod Med 2005 Dec;50(12):933-9. PMID: 16444894
Benign breast pain in women: a practical approach to evaluation and treatment.
Norlock FE
J Am Med Womens Assoc (1972) 2002 Spring;57(2):85-90. PMID: 11991427
Fibrocystic breast disease: pathophysiology, pathomorphology, clinical picture, and management.
Vorherr H
Am J Obstet Gynecol 1986 Jan;154(1):161-79. doi: 10.1016/0002-9378(86)90421-7. PMID: 3511705

Recent clinical studies

Therapy

The evaluation of the effect of metformin on breast fibrocystic disease.
Talaei A, Moradi A, Rafiei F
Breast Dis 2017;37(2):49-53. doi: 10.3233/BD-160256. PMID: 28598826
Estriol combined with glatiramer acetate for women with relapsing-remitting multiple sclerosis: a randomised, placebo-controlled, phase 2 trial.
Voskuhl RR, Wang H, Wu TC, Sicotte NL, Nakamura K, Kurth F, Itoh N, Bardens J, Bernard JT, Corboy JR, Cross AH, Dhib-Jalbut S, Ford CC, Frohman EM, Giesser B, Jacobs D, Kasper LH, Lynch S, Parry G, Racke MK, Reder AT, Rose J, Wingerchuk DM, MacKenzie-Graham AJ, Arnold DL, Tseng CH, Elashoff R
Lancet Neurol 2016 Jan;15(1):35-46. Epub 2015 Nov 29 doi: 10.1016/S1474-4422(15)00322-1. PMID: 26621682

Prognosis

Characterization and modulation of a prolactin receptor mRNA isoform in normal and tumoral human breast tissues.
Laud K, Gourdou I, Belair L, Peyrat JP, Djiane J
Int J Cancer 2000 Mar 15;85(6):771-6. doi: 10.1002/(sici)1097-0215(20000315)85:6<771::aid-ijc5>3.0.co;2-y. PMID: 10709093

Clinical prediction guides

Estriol combined with glatiramer acetate for women with relapsing-remitting multiple sclerosis: a randomised, placebo-controlled, phase 2 trial.
Voskuhl RR, Wang H, Wu TC, Sicotte NL, Nakamura K, Kurth F, Itoh N, Bardens J, Bernard JT, Corboy JR, Cross AH, Dhib-Jalbut S, Ford CC, Frohman EM, Giesser B, Jacobs D, Kasper LH, Lynch S, Parry G, Racke MK, Reder AT, Rose J, Wingerchuk DM, MacKenzie-Graham AJ, Arnold DL, Tseng CH, Elashoff R
Lancet Neurol 2016 Jan;15(1):35-46. Epub 2015 Nov 29 doi: 10.1016/S1474-4422(15)00322-1. PMID: 26621682
Characterization and modulation of a prolactin receptor mRNA isoform in normal and tumoral human breast tissues.
Laud K, Gourdou I, Belair L, Peyrat JP, Djiane J
Int J Cancer 2000 Mar 15;85(6):771-6. doi: 10.1002/(sici)1097-0215(20000315)85:6<771::aid-ijc5>3.0.co;2-y. PMID: 10709093

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

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    Reviews

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