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Childhood Non-Hodgkin Lymphoma

MedGen UID:
66308
Concept ID:
C0220612
Neoplastic Process
Synonyms: Childhood Non-Hodgkin's Lymphoma; Pediatric Non-Hodgkin Lymphoma; Pediatric Non-Hodgkin's Lymphoma

Definition

Non-Hodgkin lymphoma occurring in childhood. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChildhood Non-Hodgkin Lymphoma

Professional guidelines

PubMed

Ehrhardt MJ, Dixon SB, Belsky J, Hochberg J
Best Pract Res Clin Haematol 2023 Mar;36(1):101443. Epub 2023 Feb 3 doi: 10.1016/j.beha.2023.101443. PMID: 36907640
Moser O, Zimmermann M, Meyer U, Klapper W, Oschlies I, Schrappe M, Attarbaschi A, Mann G, Niggli F, Spix C, Kontny U, Klingebiel T, Reiter A, Burkhardt B, Woessmann W
Haematologica 2021 May 1;106(5):1390-1400. doi: 10.3324/haematol.2019.244780. PMID: 32299903Free PMC Article
Reiter A
Hematology Am Soc Hematol Educ Program 2007:285-96. doi: 10.1182/asheducation-2007.1.285. PMID: 18024642

Recent clinical studies

Etiology

Ehrhardt MJ, Dixon SB, Belsky J, Hochberg J
Best Pract Res Clin Haematol 2023 Mar;36(1):101443. Epub 2023 Feb 3 doi: 10.1016/j.beha.2023.101443. PMID: 36907640
Moser O, Zimmermann M, Meyer U, Klapper W, Oschlies I, Schrappe M, Attarbaschi A, Mann G, Niggli F, Spix C, Kontny U, Klingebiel T, Reiter A, Burkhardt B, Woessmann W
Haematologica 2021 May 1;106(5):1390-1400. doi: 10.3324/haematol.2019.244780. PMID: 32299903Free PMC Article
Minard-Colin V, Aupérin A, Pillon M, Burke GAA, Barkauskas DA, Wheatley K, Delgado RF, Alexander S, Uyttebroeck A, Bollard CM, Zsiros J, Csoka M, Kazanowska B, Chiang AK, Miles RR, Wotherspoon A, Adamson PC, Vassal G, Patte C, Gross TG; European Intergroup for Childhood Non-Hodgkin Lymphoma; Children’s Oncology Group
N Engl J Med 2020 Jun 4;382(23):2207-2219. doi: 10.1056/NEJMoa1915315. PMID: 32492302Free PMC Article
Ehrhardt MJ, Hochberg J, Bjornard KL, Brinkman TM
Br J Haematol 2019 Jun;185(6):1099-1110. Epub 2019 Feb 3 doi: 10.1111/bjh.15775. PMID: 30714126
Reiter A
Klin Padiatr 2013 May;225 Suppl 1:S87-93. Epub 2013 May 22 doi: 10.1055/s-0033-1337969. PMID: 23700066

Diagnosis

Beishuizen A, Mellgren K, Andrés M, Auperin A, Bacon CM, Bomken S, Burke GAA, Burkhardt B, Brugieres L, Chiang AKS, Damm-Welk C, d'Amore E, Horibe K, Kabickova E, Khanam T, Kontny U, Klapper W, Lamant L, Le Deley MC, Loeffen J, Macintyre E, Mann G, Meyer-Wentrup F, Michgehl U, Minard-Colin V, Mussolin L, Oschlies I, Patte C, Pillon M, Reiter A, Rigaud C, Roncery L, Salaverria I, Simonitsch-Klupp I, Uyttebroeck A, Verdu-Amoros J, Williams D, Woessmann W, Wotherspoon A, Wrobel G, Zimmermann M, Attarbaschi A, Turner SD; European Intergroup for Childhood Non-Hodgkin Lymphoma
Lancet Haematol 2023 Mar;10(3):e213-e224. doi: 10.1016/S2352-3026(22)00374-X. PMID: 36858678
Moser O, Zimmermann M, Meyer U, Klapper W, Oschlies I, Schrappe M, Attarbaschi A, Mann G, Niggli F, Spix C, Kontny U, Klingebiel T, Reiter A, Burkhardt B, Woessmann W
Haematologica 2021 May 1;106(5):1390-1400. doi: 10.3324/haematol.2019.244780. PMID: 32299903Free PMC Article
Attarbaschi A, Abla O, Arias Padilla L, Beishuizen A, Burke GAA, Brugières L, Bruneau J, Burkhardt B, d'Amore ESG, Klapper W, Kontny U, Pillon M, Taj M, Turner SD, Uyttebroeck A, Woessmann W, Mellgren K
Pediatr Blood Cancer 2020 Aug;67(8):e28416. Epub 2020 May 26 doi: 10.1002/pbc.28416. PMID: 32452165
Ehrhardt MJ, Hochberg J, Bjornard KL, Brinkman TM
Br J Haematol 2019 Jun;185(6):1099-1110. Epub 2019 Feb 3 doi: 10.1111/bjh.15775. PMID: 30714126
Reiter A
Klin Padiatr 2013 May;225 Suppl 1:S87-93. Epub 2013 May 22 doi: 10.1055/s-0033-1337969. PMID: 23700066

Therapy

Minard-Colin V, Aupérin A, Pillon M, Burke GAA, Barkauskas DA, Wheatley K, Delgado RF, Alexander S, Uyttebroeck A, Bollard CM, Zsiros J, Csoka M, Kazanowska B, Chiang AK, Miles RR, Wotherspoon A, Adamson PC, Vassal G, Patte C, Gross TG; European Intergroup for Childhood Non-Hodgkin Lymphoma; Children’s Oncology Group
N Engl J Med 2020 Jun 4;382(23):2207-2219. doi: 10.1056/NEJMoa1915315. PMID: 32492302Free PMC Article
Larose H, Burke GAA, Lowe EJ, Turner SD
Br J Haematol 2019 Jun;185(6):1043-1054. Epub 2019 Jan 25 doi: 10.1111/bjh.15763. PMID: 30681723
Mellgren K, Attarbaschi A, Abla O, Alexander S, Bomken S, Bubanska E, Chiang A, Csóka M, Fedorova A, Kabickova E, Kapuscinska-Kemblowska L, Kobayashi R, Krenova Z, Meyer-Wentrup F, Miakova N, Pillon M, Plat G, Uyttebroeck A, Williams D, Wróbel G, Kontny U; European Intergroup for Childhood Non-Hodgkin Lymphoma (EICNHL) and the international Berlin-Frankfurt-Münster (i-BFM) Group
Ann Hematol 2016 Aug;95(8):1295-305. Epub 2016 Jun 7 doi: 10.1007/s00277-016-2722-y. PMID: 27270301
Reiter A
Klin Padiatr 2013 May;225 Suppl 1:S87-93. Epub 2013 May 22 doi: 10.1055/s-0033-1337969. PMID: 23700066
Lancet 1987 Jun 20;1(8547):1410-2. PMID: 2884500

Prognosis

Moser O, Zimmermann M, Meyer U, Klapper W, Oschlies I, Schrappe M, Attarbaschi A, Mann G, Niggli F, Spix C, Kontny U, Klingebiel T, Reiter A, Burkhardt B, Woessmann W
Haematologica 2021 May 1;106(5):1390-1400. doi: 10.3324/haematol.2019.244780. PMID: 32299903Free PMC Article
Minard-Colin V, Aupérin A, Pillon M, Burke GAA, Barkauskas DA, Wheatley K, Delgado RF, Alexander S, Uyttebroeck A, Bollard CM, Zsiros J, Csoka M, Kazanowska B, Chiang AK, Miles RR, Wotherspoon A, Adamson PC, Vassal G, Patte C, Gross TG; European Intergroup for Childhood Non-Hodgkin Lymphoma; Children’s Oncology Group
N Engl J Med 2020 Jun 4;382(23):2207-2219. doi: 10.1056/NEJMoa1915315. PMID: 32492302Free PMC Article
Larose H, Burke GAA, Lowe EJ, Turner SD
Br J Haematol 2019 Jun;185(6):1043-1054. Epub 2019 Jan 25 doi: 10.1111/bjh.15763. PMID: 30681723
Reiter A
Klin Padiatr 2013 May;225 Suppl 1:S87-93. Epub 2013 May 22 doi: 10.1055/s-0033-1337969. PMID: 23700066
Reiter A
Hematology Am Soc Hematol Educ Program 2007:285-96. doi: 10.1182/asheducation-2007.1.285. PMID: 18024642

Clinical prediction guides

Hvidtfeldt UA, Erdmann F, Urhoj SK, Brandt J, Geels C, Ketzel M, Frohn LM, Christensen JH, Sørensen M, Raaschou-Nielsen O
Int J Environ Res Public Health 2020 Dec 1;17(23) doi: 10.3390/ijerph17238949. PMID: 33271946Free PMC Article
Minard-Colin V, Aupérin A, Pillon M, Burke GAA, Barkauskas DA, Wheatley K, Delgado RF, Alexander S, Uyttebroeck A, Bollard CM, Zsiros J, Csoka M, Kazanowska B, Chiang AK, Miles RR, Wotherspoon A, Adamson PC, Vassal G, Patte C, Gross TG; European Intergroup for Childhood Non-Hodgkin Lymphoma; Children’s Oncology Group
N Engl J Med 2020 Jun 4;382(23):2207-2219. doi: 10.1056/NEJMoa1915315. PMID: 32492302Free PMC Article
O'Rourke E, Malone A, O'Marcaigh A, Storey L, Betts D, McDermott M, Smith OP
Ir Med J 2020 Jan 16;113(1):6. PMID: 32298568
Ehrhardt MJ, Mulrooney DA, Li C, Baassiri MJ, Bjornard K, Sandlund JT, Brinkman TM, Huang IC, Srivastava DK, Ness KK, Robison LL, Hudson MM, Krull KR
Cancer 2018 Jan 15;124(2):417-425. Epub 2017 Sep 15 doi: 10.1002/cncr.31019. PMID: 28915338Free PMC Article
van Waas M, Neggers SJ, Te Winkel ML, Beishuizen A, Pieters R, van den Heuvel-Eibrink MM
Ann Oncol 2012 Jun;23(6):1626-32. Epub 2011 Nov 2 doi: 10.1093/annonc/mdr511. PMID: 22048153

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