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Endolymphatic hydrops

MedGen UID:
60183
•Concept ID:
C0206586
•
Disease or Syndrome
Synonyms: Endolymphatic Hydrops; Hydrops, Endolymphatic
SNOMED CT: Endolymphatic hydrops (9794007); Cochlear hydrops (70831000119103); Labyrinthine hydrops (27621000119100)
 
Monarch Initiative: MONDO:0006744

Definition

An accumulation of endolymph in the inner ear (labyrinth) leading to buildup of pressure and distortion of intralabyrinthine structures, such as cochlea and semicircular canals. It is characterized by sensorineural hearing loss; tinnitus; and sometimes vertigo. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEndolymphatic hydrops

Professional guidelines

PubMed

Clinical Practice Guideline: Ménière's Disease Executive Summary.
Basura GJ, Adams ME, Monfared A, Schwartz SR, Antonelli PJ, Burkard R, Bush ML, Bykowski J, Colandrea M, Derebery J, Kelly EA, Kerber KA, Koopman CF, Kuch AA, Marcolini E, McKinnon BJ, Ruckenstein MJ, Valenzuela CV, Vosooney A, Walsh SA, Nnacheta LC, Dhepyasuwan N, Buchanan EM
Otolaryngol Head Neck Surg 2020 Apr;162(4):415-434. doi: 10.1177/0194599820909439. PMID: 32267820
Clinical Practice Guideline: Ménière's Disease.
Basura GJ, Adams ME, Monfared A, Schwartz SR, Antonelli PJ, Burkard R, Bush ML, Bykowski J, Colandrea M, Derebery J, Kelly EA, Kerber KA, Koopman CF, Kuch AA, Marcolini E, McKinnon BJ, Ruckenstein MJ, Valenzuela CV, Vosooney A, Walsh SA, Nnacheta LC, Dhepyasuwan N, Buchanan EM
Otolaryngol Head Neck Surg 2020 Apr;162(2_suppl):S1-S55. doi: 10.1177/0194599820909438. PMID: 32267799
Treatment of dizziness: an interdisciplinary update.
Spiegel R, Rust H, Baumann T, Friedrich H, Sutter R, Göldlin M, Rosin C, Müri R, Mantokoudis G, Bingisser R, Strupp M, Kalla R
Swiss Med Wkly 2017;147:w14566. Epub 2017 Dec 27 doi: 10.4414/smw.2017.14566. PMID: 29282702

Recent clinical studies

Etiology

MRI can help differentiate Ménière's disease from other menieriform diseases.
Li J, Li L, Jin X, Hu N, Kong X, Wang L, Li X, Dou W, Sun L, Li C, Gong R
Sci Rep 2023 Dec 6;13(1):21527. doi: 10.1038/s41598-023-49066-5. PMID: 38057393Free PMC Article
Ménière's disease and allergy: Epidemiology, pathogenesis, and therapy.
Xu W, Li X, Song Y, Kong L, Zhang N, Liu J, Li G, Fan Z, Lyu Y, Zhang D, Wang H, Li N
Clin Exp Med 2023 Nov;23(7):3361-3371. Epub 2023 Sep 24 doi: 10.1007/s10238-023-01192-0. PMID: 37743423
The value of four stage vestibular hydrops grading and asymmetric perilymphatic enhancement in the diagnosis of Menière's disease on MRI.
Bernaerts A, Vanspauwen R, Blaivie C, van Dinther J, Zarowski A, Wuyts FL, Vanden Bossche S, Offeciers E, Casselman JW, De Foer B
Neuroradiology 2019 Apr;61(4):421-429. Epub 2019 Feb 5 doi: 10.1007/s00234-019-02155-7. PMID: 30719545Free PMC Article
Endolymphatic hydrops perspectives 2012.
Pierce NE, Antonelli PJ
Curr Opin Otolaryngol Head Neck Surg 2012 Oct;20(5):416-9. doi: 10.1097/MOO.0b013e328357a6c8. PMID: 22902416
Bilateral Ménière's disease.
Nabi S, Parnes LS
Curr Opin Otolaryngol Head Neck Surg 2009 Oct;17(5):356-62. doi: 10.1097/MOO.0b013e3283304cb3. PMID: 19617826

Diagnosis

Meniere's disease: Pathogenesis, treatments, and emerging approaches for an idiopathic bioenvironmental disorder.
Mohseni-Dargah M, Falahati Z, Pastras C, Khajeh K, Mukherjee P, Razmjou A, Stefani S, Asadnia M
Environ Res 2023 Dec 1;238(Pt 1):116972. Epub 2023 Aug 28 doi: 10.1016/j.envres.2023.116972. PMID: 37648189
Vestibular migraine or Meniere's disease: a diagnostic dilemma.
Chen JY, Guo ZQ, Wang J, Liu D, Tian E, Guo JQ, Kong WJ, Zhang SL
J Neurol 2023 Apr;270(4):1955-1968. Epub 2022 Dec 23 doi: 10.1007/s00415-022-11532-x. PMID: 36562849Free PMC Article
Secondary Endolymphatic Hydrops.
Ferster APO, Cureoglu S, Keskin N, Paparella MM, Isildak H
Otol Neurotol 2017 Jun;38(5):774-779. doi: 10.1097/MAO.0000000000001377. PMID: 28306649Free PMC Article
Menière's disease.
Espinosa-Sanchez JM, Lopez-Escamez JA
Handb Clin Neurol 2016;137:257-77. doi: 10.1016/B978-0-444-63437-5.00019-4. PMID: 27638077
What is Menière's disease? A contemporary re-evaluation of endolymphatic hydrops.
Gürkov R, Pyykö I, Zou J, Kentala E
J Neurol 2016 Apr;263 Suppl 1:S71-81. Epub 2016 Apr 15 doi: 10.1007/s00415-015-7930-1. PMID: 27083887Free PMC Article

Therapy

Clinical Practice Guideline: Ménière's Disease.
Basura GJ, Adams ME, Monfared A, Schwartz SR, Antonelli PJ, Burkard R, Bush ML, Bykowski J, Colandrea M, Derebery J, Kelly EA, Kerber KA, Koopman CF, Kuch AA, Marcolini E, McKinnon BJ, Ruckenstein MJ, Valenzuela CV, Vosooney A, Walsh SA, Nnacheta LC, Dhepyasuwan N, Buchanan EM
Otolaryngol Head Neck Surg 2020 Apr;162(2_suppl):S1-S55. doi: 10.1177/0194599820909438. PMID: 32267799
Meniere's disease.
Nakashima T, Pyykkö I, Arroll MA, Casselbrant ML, Foster CA, Manzoor NF, Megerian CA, Naganawa S, Young YH
Nat Rev Dis Primers 2016 May 12;2:16028. doi: 10.1038/nrdp.2016.28. PMID: 27170253
Endolymphatic hydrops perspectives 2012.
Pierce NE, Antonelli PJ
Curr Opin Otolaryngol Head Neck Surg 2012 Oct;20(5):416-9. doi: 10.1097/MOO.0b013e328357a6c8. PMID: 22902416
Bilateral Ménière's disease.
Nabi S, Parnes LS
Curr Opin Otolaryngol Head Neck Surg 2009 Oct;17(5):356-62. doi: 10.1097/MOO.0b013e3283304cb3. PMID: 19617826
Ménière's disease.
Minor LB, Schessel DA, Carey JP
Curr Opin Neurol 2004 Feb;17(1):9-16. doi: 10.1097/00019052-200402000-00004. PMID: 15090872

Prognosis

Auditory biophysics of endolymphatic hydrops.
Avan P, Djennaoui I
J Vestib Res 2021;31(4):277-281. doi: 10.3233/VES-200719. PMID: 33136084
Imaging of the temporal bone.
Touska P, Connor SEJ
Clin Radiol 2020 Sep;75(9):658-674. Epub 2020 Jul 18 doi: 10.1016/j.crad.2020.06.013. PMID: 32690241
Menière's disease.
Espinosa-Sanchez JM, Lopez-Escamez JA
Handb Clin Neurol 2016;137:257-77. doi: 10.1016/B978-0-444-63437-5.00019-4. PMID: 27638077
Endolymphatic hydrops perspectives 2012.
Pierce NE, Antonelli PJ
Curr Opin Otolaryngol Head Neck Surg 2012 Oct;20(5):416-9. doi: 10.1097/MOO.0b013e328357a6c8. PMID: 22902416
Bilateral Ménière's disease.
Nabi S, Parnes LS
Curr Opin Otolaryngol Head Neck Surg 2009 Oct;17(5):356-62. doi: 10.1097/MOO.0b013e3283304cb3. PMID: 19617826

Clinical prediction guides

MRI can help differentiate Ménière's disease from other menieriform diseases.
Li J, Li L, Jin X, Hu N, Kong X, Wang L, Li X, Dou W, Sun L, Li C, Gong R
Sci Rep 2023 Dec 6;13(1):21527. doi: 10.1038/s41598-023-49066-5. PMID: 38057393Free PMC Article
HASHIMOTO THYROIDITIS AND VESTIBULAR DYSFUNCTION.
Chiarella G, Russo D, Monzani F, Petrolo C, Fattori B, Pasqualetti G, Cassandro E, Costante G
Endocr Pract 2017 Jul;23(7):863-868. Epub 2017 May 23 doi: 10.4158/EP161635.RA. PMID: 28534686
Menière's disease.
Espinosa-Sanchez JM, Lopez-Escamez JA
Handb Clin Neurol 2016;137:257-77. doi: 10.1016/B978-0-444-63437-5.00019-4. PMID: 27638077
Bilateral Ménière's disease.
Nabi S, Parnes LS
Curr Opin Otolaryngol Head Neck Surg 2009 Oct;17(5):356-62. doi: 10.1097/MOO.0b013e3283304cb3. PMID: 19617826
Post-traumatic hydrops.
DiBiase P, Arriaga MA
Otolaryngol Clin North Am 1997 Dec;30(6):1117-22. PMID: 9386247

Recent systematic reviews

Potential Application of Hydrops MR Imaging: A Systematic Review.
Young YH, Lin KT
J Otolaryngol Head Neck Surg 2024 Jan-Dec;53:19160216241250350. doi: 10.1177/19160216241250350. PMID: 38888936Free PMC Article
Temporal changes in endolymphatic hydrops on MRI with or without intervention: A systematic review.
Mavrommatis MA, Kaul VF, Chow K, Fan CJ, Bellaire CP, Cosetti MK, Wanna GB, Perez E
Am J Otolaryngol 2023 Mar-Apr;44(2):103764. Epub 2022 Dec 28 doi: 10.1016/j.amjoto.2022.103764. PMID: 36587603
Systematic review of the diagnostic value of hydrops MRI in relation to audiovestibular function tests (electrocochleography, cervical vestibular evoked myogenic potential and caloric test).
Orimoto KY, Vartanyan M, O'Leary SJ
Eur Arch Otorhinolaryngol 2023 Mar;280(3):947-962. Epub 2022 Oct 27 doi: 10.1007/s00405-022-07702-2. PMID: 36301356Free PMC Article
Diagnostic Value of Vestibular Evoked Myogenic Potentials in Endolymphatic Hydrops: A Meta-Analysis.
Zhang S, Leng Y, Liu B, Shi H, Lu M, Kong W
Sci Rep 2015 Oct 12;5:14951. doi: 10.1038/srep14951. PMID: 26455332Free PMC Article
Electrocochleography for Ménière's disease: is it reliable?
Lamounier P, Gobbo DA, Souza TS, Oliveira CA, Bahmad F Jr
Braz J Otorhinolaryngol 2014 Nov-Dec;80(6):527-32. Epub 2014 Aug 27 doi: 10.1016/j.bjorl.2014.08.010. PMID: 25443316Free PMC Article

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