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Labyrinthine disorder

MedGen UID:
44049
•Concept ID:
C0022890
•
Disease or Syndrome
Synonyms: Ear Disease, Inner; Ear Diseases, Inner; Inner Ear Disease; Inner Ear Diseases; Labyrinth Disease; Labyrinth Diseases
SNOMED CT: Labyrinthine disorder (20425006)

Definition

A condition affecting the bony or membranous labyrinth of the inner ear and which may be characterized by vertigo, dysequilibrium, nystagmus, or hearing loss. [from NCI]

Professional guidelines

PubMed

Benign paroxysmal positional vertigo: Effective diagnosis and treatment.
Cole SR, Honaker JA
Cleve Clin J Med 2022 Nov 1;89(11):653-662. doi: 10.3949/ccjm.89a.21057. PMID: 36319052
Vestibular Rehabilitation for Peripheral Vestibular Hypofunction: An Updated Clinical Practice Guideline From the Academy of Neurologic Physical Therapy of the American Physical Therapy Association.
Hall CD, Herdman SJ, Whitney SL, Anson ER, Carender WJ, Hoppes CW, Cass SP, Christy JB, Cohen HS, Fife TD, Furman JM, Shepard NT, Clendaniel RA, Dishman JD, Goebel JA, Meldrum D, Ryan C, Wallace RL, Woodward NJ
J Neurol Phys Ther 2022 Apr 1;46(2):118-177. doi: 10.1097/NPT.0000000000000382. PMID: 34864777Free PMC Article
Clinical Practice Guideline: Benign Paroxysmal Positional Vertigo (Update).
Bhattacharyya N, Gubbels SP, Schwartz SR, Edlow JA, El-Kashlan H, Fife T, Holmberg JM, Mahoney K, Hollingsworth DB, Roberts R, Seidman MD, Steiner RW, Do BT, Voelker CC, Waguespack RW, Corrigan MD
Otolaryngol Head Neck Surg 2017 Mar;156(3_suppl):S1-S47. doi: 10.1177/0194599816689667. PMID: 28248609

Recent clinical studies

Etiology

Benign paroxysmal positional vertigo and its variants.
Nuti D, Masini M, Mandalà M
Handb Clin Neurol 2016;137:241-56. doi: 10.1016/B978-0-444-63437-5.00018-2. PMID: 27638076
What proportion of patients referred to an otolaryngology vertigo clinic have an otological cause for their symptoms?
Arya AK, Nunez DA
J Laryngol Otol 2008 Feb;122(2):145-9. Epub 2007 May 25 doi: 10.1017/S0022215107008559. PMID: 17524169
Postirradiation vertigo in nasopharyngeal carcinoma survivors.
Young YH, Ko JY, Sheen TS
Otol Neurotol 2004 May;25(3):366-70. doi: 10.1097/00129492-200405000-00027. PMID: 15129119
Screening for depression among neuro-otology patients with and without identifiable vestibular lesions.
Grunfeld EA, Gresty MA, Bronstein AM, Jahanshahi M
Int J Audiol 2003 Apr;42(3):161-5. doi: 10.3109/14992020309090425. PMID: 12705781
A relationship between autoimmune thyroiditis and benign paroxysmal positional vertigo?
Modugno GC, Pirodda A, Ferri GG, Montana T, Rasciti L, Ceroni AR
Med Hypotheses 2000 Apr;54(4):614-5. doi: 10.1054/mehy.1999.0905. PMID: 10859648

Diagnosis

Benign paroxysmal positional vertigo and its variants.
Nuti D, Masini M, Mandalà M
Handb Clin Neurol 2016;137:241-56. doi: 10.1016/B978-0-444-63437-5.00018-2. PMID: 27638076
Enlarged vestibular aqueduct (EVA) related with recurrent benign paroxysmal positional vertigo (BPPV).
Manzari L
Med Hypotheses 2008;70(1):61-5. Epub 2007 Jun 27 doi: 10.1016/j.mehy.2007.04.032. PMID: 17590526
Neuro-otological emergencies.
Seemungal BM
Curr Opin Neurol 2007 Feb;20(1):32-9. doi: 10.1097/WCO.0b013e3280122514. PMID: 17215686
Isolated acute vertigo in the elderly; vestibular or vascular disease?
Norrving B, Magnusson M, Holtås S
Acta Neurol Scand 1995 Jan;91(1):43-8. doi: 10.1111/j.1600-0404.1995.tb05841.x. PMID: 7732773
Acute labyrinthine disorders.
Lindeman RC
Otolaryngol Clin North Am 1979 May;12(2):375-87. PMID: 460880

Therapy

Postirradiation vertigo in nasopharyngeal carcinoma survivors.
Young YH, Ko JY, Sheen TS
Otol Neurotol 2004 May;25(3):366-70. doi: 10.1097/00129492-200405000-00027. PMID: 15129119

Prognosis

Cerebellar infarction--a presentation of vertigo.
Rubenstein RL, Norman DM, Schindler RA, Kaseff L
Laryngoscope 1980 Mar;90(3):505-14. doi: 10.1002/lary.5540900319. PMID: 7359972

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