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Photoallergic dermatitis

MedGen UID:
56514
•Concept ID:
C0162824
•
Disease or Syndrome
Synonyms: Contact Dermatitides, Photoallergic; Contact Dermatitides, Photosensitive; Contact Dermatitis, Photoallergic; Contact Dermatitis, Photosensitive; Dermatitides, Photoallergic; Dermatitides, Photoallergic Contact; Dermatitides, Photocontact; Dermatitides, Photosensitive Contact; Dermatitis, Contact, Photoallergic; Dermatitis, Contact, Photosensitive; Dermatitis, Photoallergic; Dermatitis, Photoallergic Contact; Dermatitis, Photocontact; Dermatitis, Photosensitive Contact; Photoallergic Contact Dermatitides; Photoallergic Contact Dermatitis; Photoallergic Dermatitides; Photoallergic Dermatitis; Photocontact Dermatitides; Photocontact Dermatitis; Photosensitive Contact Dermatitides; Photosensitive Contact Dermatitis
SNOMED CT: Allergic photocontact eczema (111209006); Photoallergic dermatitis (111209006); Photoallergic contact dermatitis (111209006); Photoallergic eczema (111209006)
 
Monarch Initiative: MONDO:0006596

Definition

A delayed hypersensitivity involving the reaction between sunlight or other radiant energy source and a chemical substance to which the individual has been previously exposed and sensitized. It manifests as a papulovesicular, eczematous, or exudative dermatitis occurring chiefly on the light-exposed areas of the skin. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPhotoallergic dermatitis

Professional guidelines

PubMed

Allergic contact dermatitis: Patient management and education.
Mowad CM, Anderson B, Scheinman P, Pootongkam S, Nedorost S, Brod B
J Am Acad Dermatol 2016 Jun;74(6):1043-54. doi: 10.1016/j.jaad.2015.02.1144. PMID: 27185422
Photodermatoses: classification, evaluation and management.
Bylaite M, Grigaitiene J, Lapinskaite GS
Br J Dermatol 2009 Nov;161 Suppl 3:61-8. doi: 10.1111/j.1365-2133.2009.09451.x. PMID: 19775359
Recognition and management of cutaneous photosensitivity.
Hearn R
Practitioner 2005 Jun;249(1671):418, 420, 422-4, passim. PMID: 15966276

Recent clinical studies

Etiology

A sunlit skin.
Cozzi G, Berti I, Barbi E, Calligaris L
J Paediatr Child Health 2019 Apr;55(4):482. doi: 10.1111/jpc.2_14330. PMID: 30957337
Photodermatoses in skin of colour.
Gutierrez D, Gaulding JV, Motta Beltran AF, Lim HW, Pritchett EN
J Eur Acad Dermatol Venereol 2018 Nov;32(11):1879-1886. Epub 2018 Jul 15 doi: 10.1111/jdv.15115. PMID: 29888465
Chemical photoallergy: photobiochemical mechanisms, classification, and risk assessments.
Onoue S, Seto Y, Sato H, Nishida H, Hirota M, Ashikaga T, Api AM, Basketter D, Tokura Y
J Dermatol Sci 2017 Jan;85(1):4-11. Epub 2016 Aug 6 doi: 10.1016/j.jdermsci.2016.08.005. PMID: 27528585
Benzophenones.
Heurung AR, Raju SI, Warshaw EM
Dermatitis 2014 Jan-Feb;25(1):3-10. doi: 10.1097/DER.0000000000000025. PMID: 24407064
Photodermatoses with onset in the elderly.
Trakatelli M, Charalampidis S, Novakovic LB, Patsatsi A, Kalabalikis D, Sotiriadis D
Br J Dermatol 2009 Nov;161 Suppl 3:69-77. doi: 10.1111/j.1365-2133.2009.09452.x. PMID: 19775360

Diagnosis

Lime Dermatitis.
Belcadi J, Oulad Ali S, Senouci K
Dermatitis 2024 Sep-Oct;35(5):429-430. Epub 2024 Feb 22 doi: 10.1089/derm.2024.0017. PMID: 38387001
Ketoprofen-induced photoallergic dermatitis.
Nihira T, Hagiwara Y
Pediatr Int 2019 Jun;61(6):610-611. Epub 2019 Jun 11 doi: 10.1111/ped.13850. PMID: 31184407Free PMC Article
Photoallergic contact dermatitis.
Consuegra Romero G, Castro Gutiérrez B, González López MA
Eur J Intern Med 2017 Mar;38:e4-e5. Epub 2016 Aug 17 doi: 10.1016/j.ejim.2016.08.013. PMID: 27544569
Drug-induced photosensitivity: Photoallergic and phototoxic reactions.
Monteiro AF, Rato M, Martins C
Clin Dermatol 2016 Sep-Oct;34(5):571-81. Epub 2016 May 20 doi: 10.1016/j.clindermatol.2016.05.006. PMID: 27638435
Photoallergy.
Wilm A, Berneburg M
J Dtsch Dermatol Ges 2015 Jan;13(1):7-12; quiz 13. doi: 10.1111/ddg.12535. PMID: 25640484

Therapy

Lime Dermatitis.
Belcadi J, Oulad Ali S, Senouci K
Dermatitis 2024 Sep-Oct;35(5):429-430. Epub 2024 Feb 22 doi: 10.1089/derm.2024.0017. PMID: 38387001
Drug-induced photosensitivity: Photoallergic and phototoxic reactions.
Monteiro AF, Rato M, Martins C
Clin Dermatol 2016 Sep-Oct;34(5):571-81. Epub 2016 May 20 doi: 10.1016/j.clindermatol.2016.05.006. PMID: 27638435
Photoallergy.
Wilm A, Berneburg M
J Dtsch Dermatol Ges 2015 Jan;13(1):7-12; quiz 13. doi: 10.1111/ddg.12535. PMID: 25640484
Benzophenones.
Heurung AR, Raju SI, Warshaw EM
Dermatitis 2014 Jan-Feb;25(1):3-10. doi: 10.1097/DER.0000000000000025. PMID: 24407064
Ketoprofen allergic reactions.
Cantisani C, Grieco T, Faina V, Mattozzi C, Bohnenberger H, Silvestri E, Calvieri S
Recent Pat Inflamm Allergy Drug Discov 2010 Jan;4(1):58-64. doi: 10.2174/187221310789895595. PMID: 19832694

Prognosis

A sunlit skin.
Cozzi G, Berti I, Barbi E, Calligaris L
J Paediatr Child Health 2019 Apr;55(4):482. doi: 10.1111/jpc.2_14330. PMID: 30957337
A sunlit skin.
Cozzi G, Berti I, Barbi E, Calligaris L
J Paediatr Child Health 2019 Apr;55(4):481. doi: 10.1111/jpc.1_14330. PMID: 30957336
Photodermatoses in skin of colour.
Gutierrez D, Gaulding JV, Motta Beltran AF, Lim HW, Pritchett EN
J Eur Acad Dermatol Venereol 2018 Nov;32(11):1879-1886. Epub 2018 Jul 15 doi: 10.1111/jdv.15115. PMID: 29888465
Chemical photoallergy: photobiochemical mechanisms, classification, and risk assessments.
Onoue S, Seto Y, Sato H, Nishida H, Hirota M, Ashikaga T, Api AM, Basketter D, Tokura Y
J Dermatol Sci 2017 Jan;85(1):4-11. Epub 2016 Aug 6 doi: 10.1016/j.jdermsci.2016.08.005. PMID: 27528585
Update on photodermatoses.
Santoro FA, Lim HW
Semin Cutan Med Surg 2011 Dec;30(4):229-38. doi: 10.1016/j.sder.2011.07.007. PMID: 22123421

Clinical prediction guides

RIFM fragrance ingredient safety assessment, 6,6-dimethylbicyclo[3.1.1]hept-2-ene-2-propionaldehyde, CAS Registry Number 33885-51-7.
Api AM, Belsito D, Botelho D, Bruze M, Burton GA Jr, Buschmann J, Cancellieri MA, Dagli ML, Date M, Dekant W, Deodhar C, Fryer AD, Jones L, Joshi K, Kumar M, Lapczynski A, Lavelle M, Lee I, Liebler DC, Moustakas H, Na M, Penning TM, Ritacco G, Romine J, Sadekar N, Schultz TW, Selechnik D, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, Tokura Y
Food Chem Toxicol 2022 Jan 15;159 Suppl 1:112658. Epub 2021 Nov 4 doi: 10.1016/j.fct.2021.112658. PMID: 34742791
European photopatch test baseline series: A 3-year experience.
Subiabre-Ferrer D, Esteve-Martínez A, Blasco-Encinas R, Sierra-Talamantes C, Pérez-Ferriols A, Zaragoza-Ninet V
Contact Dermatitis 2019 Jan;80(1):5-8. Epub 2018 Sep 17 doi: 10.1111/cod.13118. PMID: 30221361
Cutaneous adverse effects of targeted therapies: Part I: Inhibitors of the cellular membrane.
Macdonald JB, Macdonald B, Golitz LE, LoRusso P, Sekulic A
J Am Acad Dermatol 2015 Feb;72(2):203-18; quiz 219-20. doi: 10.1016/j.jaad.2014.07.032. PMID: 25592338
Sunscreens and vitamin E provide some protection to the skin immune system from solar-simulated UV radiation.
Halliday GM, Yuen KS, Bestak R, Barnetson RS
Australas J Dermatol 1998 May;39(2):71-5. doi: 10.1111/j.1440-0960.1998.tb01251.x. PMID: 9611373
Enoxacin photosensitivity.
Kang JS, Kim TH, Park KB, Chung BH, Youn JI
Photodermatol Photoimmunol Photomed 1993 Aug;9(4):159-61. PMID: 8318434

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