U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Malignant Neoplasm of the Lower Third of the Esophagus

MedGen UID:
57556
•Concept ID:
C0153415
•
Neoplastic Process
Synonyms: Ca lower third esophagus; Malignant Lower Third of Esophagus Neoplasm; Malignant Lower Third of Esophagus Tumor; Malignant Lower Third of the Esophagus Neoplasm; Malignant Lower Third of the Esophagus Tumor; Malignant Neoplasm of Distal Third of Esophagus; Malignant neoplasm of lower third of esophagus; Malignant Neoplasm of Lower Third of Esophagus; Malignant Neoplasm of the Distal Third of the Esophagus; Malignant Tumor of Distal Third of Esophagus; Malignant tumor of lower third of esophagus; Malignant Tumor of Lower Third of Esophagus; Malignant Tumor of the Distal Third of the Esophagus; Malignant Tumor of the Lower Third of the Esophagus
SNOMED CT: Ca lower third esophagus (187727005); Malignant neoplasm of lower third of esophagus (187727005); Malignant tumor of lower third of esophagus (187727005)

Definition

A primary or metastatic malignant neoplasm involving the lower third segment of the esophagus. [from NCI]

Professional guidelines

PubMed

Clinical characteristics and management of gastric tube cancer after esophagectomy.
Shirakawa Y, Noma K, Maeda N, Ninomiya T, Tanabe S, Kikuchi S, Kuroda S, Nishizaki M, Kagawa S, Kawahara Y, Okada H, Fujiwara T
Esophagus 2018 Jul;15(3):180-189. Epub 2018 Mar 27 doi: 10.1007/s10388-018-0611-2. PMID: 29951985
Differential role of microRNAs in the pathogenesis and treatment of Esophageal cancer.
Hemmatzadeh M, Mohammadi H, Karimi M, Musavishenas MH, Baradaran B
Biomed Pharmacother 2016 Aug;82:509-19. Epub 2016 Jun 4 doi: 10.1016/j.biopha.2016.05.009. PMID: 27470391
Endoscopic diagnosis and treatment of esophageal verrucous squamous cell cancer.
Sweetser S, Jacobs NL, Wong Kee Song LM
Dis Esophagus 2014 Jul;27(5):452-6. Epub 2012 Oct 15 doi: 10.1111/j.1442-2050.2012.01434.x. PMID: 23067443

Recent clinical studies

Etiology

The different prognostic factors between metastatic and nonmetastatic disease of esophageal neuroendocrine carcinoma.
Zhong L, Pan Y, Han S, Qi Q, Liao H, Jiang Y, Shen J
Indian J Cancer 2023 Oct 1;60(4):512-520. Epub 2024 Jan 10 doi: 10.4103/ijc.IJC_151_20. PMID: 38206083
Prebiotics and the Risk of Upper Digestive Tract and Stomach Cancers: The PrebiotiCa Study.
Turati F, Concina F, Bertuccio P, Fiori F, Parpinel M, Garavello W, Crispo A, Libra M, Negri E, Serraino D, La Vecchia C
J Acad Nutr Diet 2023 Dec;123(12):1772-1780. Epub 2023 Jul 17 doi: 10.1016/j.jand.2023.07.008. PMID: 37468063
The Prognostic Value of the Prognostic Nutritional Index (PNI) in Radically Resected Esophagogastric Junction Adenocarcinoma.
Ge K, Fang C, Zhu D, Yan H, Wang Q, Chen W, Wu J
Nutr Cancer 2021;73(11-12):2589-2596. Epub 2020 Nov 2 doi: 10.1080/01635581.2020.1841252. PMID: 33135475
Submucosal gland neoplasms of the esophagus: an update and review.
Nie L, Li W, Xue L, Wang L, Shen Y, Fan X
Esophagus 2020 Oct;17(4):376-384. Epub 2020 Jul 3 doi: 10.1007/s10388-020-00758-1. PMID: 32621256Free PMC Article
Endoscopic or Surgical Resection for Gastro-Esophageal Cancer.
Gockel I, Hoffmeister A
Dtsch Arztebl Int 2018 Aug 6;115(31-32):513-519. doi: 10.3238/arztebl.2018.0513. PMID: 30149830Free PMC Article

Diagnosis

Submucosal gland neoplasms of the esophagus: an update and review.
Nie L, Li W, Xue L, Wang L, Shen Y, Fan X
Esophagus 2020 Oct;17(4):376-384. Epub 2020 Jul 3 doi: 10.1007/s10388-020-00758-1. PMID: 32621256Free PMC Article
Endoscopic or Surgical Resection for Gastro-Esophageal Cancer.
Gockel I, Hoffmeister A
Dtsch Arztebl Int 2018 Aug 6;115(31-32):513-519. doi: 10.3238/arztebl.2018.0513. PMID: 30149830Free PMC Article
Esophageal cancer: pneumo-64-MDCT.
Ulla M, Cavadas D, Muñoz I, Beskow A, Seehaus A, García-Mónaco R
Abdom Imaging 2010 Aug;35(4):383-9. Epub 2009 Jun 30 doi: 10.1007/s00261-009-9554-3. PMID: 19568806
Esophageal schwannoma.
Hsu SD, Cheng YL, Chen A, Lee SC
J Formos Med Assoc 2003 May;102(5):346-8. PMID: 12874676
Tumors of the esophagus.
Hatch GF 3rd, Wertheimer-Hatch L, Hatch KF, Davis GB, Blanchard DK, Foster RS Jr, Skandalakis JE
World J Surg 2000 Apr;24(4):401-11. doi: 10.1007/s002689910065. PMID: 10706912

Therapy

Lugol-unstained lesions location in the esophagus affects the detection rate of malignancy: a population-based study.
Qin J, Liu M, Liu A, Guo C, Qi Z, Zhou R, Yang H, Li F, Duan L, Shen L, Wu Q, Liu Z, Pan Y, Liu F, Liu Y, Cai H, He Z, Ke Y
J Gastroenterol Hepatol 2023 Dec;38(12):2167-2173. Epub 2023 Sep 19 doi: 10.1111/jgh.16356. PMID: 37726891
Prophylactic ligation of the opacified thoracic duct in minimally invasive esophagectomy - feasibility and safety.
Takhellambam L, Yadav TD, Kumar H, Gupta V, Tandup C, Gorsi U, Sharma V, Mandhavdhare H, Samra T, Singh H
Langenbecks Arch Surg 2021 Nov;406(7):2515-2520. Epub 2021 Aug 19 doi: 10.1007/s00423-021-02300-y. PMID: 34410481
Endoscopic or Surgical Resection for Gastro-Esophageal Cancer.
Gockel I, Hoffmeister A
Dtsch Arztebl Int 2018 Aug 6;115(31-32):513-519. doi: 10.3238/arztebl.2018.0513. PMID: 30149830Free PMC Article
Esophageal cancer: pneumo-64-MDCT.
Ulla M, Cavadas D, Muñoz I, Beskow A, Seehaus A, García-Mónaco R
Abdom Imaging 2010 Aug;35(4):383-9. Epub 2009 Jun 30 doi: 10.1007/s00261-009-9554-3. PMID: 19568806
Radiotherapy.
Jelliffe AM
Postgrad Med J 1974 Apr;50(582):231-2. doi: 10.1136/pgmj.50.582.231. PMID: 4217448Free PMC Article

Prognosis

The different prognostic factors between metastatic and nonmetastatic disease of esophageal neuroendocrine carcinoma.
Zhong L, Pan Y, Han S, Qi Q, Liao H, Jiang Y, Shen J
Indian J Cancer 2023 Oct 1;60(4):512-520. Epub 2024 Jan 10 doi: 10.4103/ijc.IJC_151_20. PMID: 38206083
The Prognostic Value of the Prognostic Nutritional Index (PNI) in Radically Resected Esophagogastric Junction Adenocarcinoma.
Ge K, Fang C, Zhu D, Yan H, Wang Q, Chen W, Wu J
Nutr Cancer 2021;73(11-12):2589-2596. Epub 2020 Nov 2 doi: 10.1080/01635581.2020.1841252. PMID: 33135475
Differential role of microRNAs in the pathogenesis and treatment of Esophageal cancer.
Hemmatzadeh M, Mohammadi H, Karimi M, Musavishenas MH, Baradaran B
Biomed Pharmacother 2016 Aug;82:509-19. Epub 2016 Jun 4 doi: 10.1016/j.biopha.2016.05.009. PMID: 27470391
Tumors of the esophagus.
Hatch GF 3rd, Wertheimer-Hatch L, Hatch KF, Davis GB, Blanchard DK, Foster RS Jr, Skandalakis JE
World J Surg 2000 Apr;24(4):401-11. doi: 10.1007/s002689910065. PMID: 10706912
Radiotherapy.
Jelliffe AM
Postgrad Med J 1974 Apr;50(582):231-2. doi: 10.1136/pgmj.50.582.231. PMID: 4217448Free PMC Article

Clinical prediction guides

Lifestyle changes in middle age and risk of cancer: evidence from the European Prospective Investigation into Cancer and Nutrition.
Botteri E, Peveri G, Berstad P, Bagnardi V, Hoff G, Heath AK, Cross AJ, Vineis P, Dossus L, Johansson M, Freisling H, Matta K, Huybrechts I, Chen SLF, B Borch K, Sandanger TM, H Nøst T, Dahm CC, Antoniussen CS, Tin Tin S, Fournier A, Marques C, Artaud F, Sánchez MJ, Guevara M, Santiuste C, Agudo A, Bajracharya R, Katzke V, Ricceri F, Agnoli C, Bergmann MM, Schulze MB, Panico S, Masala G, Tjønneland A, Olsen A, Stocks T, Manjer J, Aizpurua-Atxega A, Weiderpass E, Riboli E, Gunter MJ, Ferrari P
Eur J Epidemiol 2024 Feb;39(2):147-159. Epub 2024 Jan 5 doi: 10.1007/s10654-023-01059-4. PMID: 38180593
Prebiotics and the Risk of Upper Digestive Tract and Stomach Cancers: The PrebiotiCa Study.
Turati F, Concina F, Bertuccio P, Fiori F, Parpinel M, Garavello W, Crispo A, Libra M, Negri E, Serraino D, La Vecchia C
J Acad Nutr Diet 2023 Dec;123(12):1772-1780. Epub 2023 Jul 17 doi: 10.1016/j.jand.2023.07.008. PMID: 37468063
The Prognostic Value of the Prognostic Nutritional Index (PNI) in Radically Resected Esophagogastric Junction Adenocarcinoma.
Ge K, Fang C, Zhu D, Yan H, Wang Q, Chen W, Wu J
Nutr Cancer 2021;73(11-12):2589-2596. Epub 2020 Nov 2 doi: 10.1080/01635581.2020.1841252. PMID: 33135475
Differential role of microRNAs in the pathogenesis and treatment of Esophageal cancer.
Hemmatzadeh M, Mohammadi H, Karimi M, Musavishenas MH, Baradaran B
Biomed Pharmacother 2016 Aug;82:509-19. Epub 2016 Jun 4 doi: 10.1016/j.biopha.2016.05.009. PMID: 27470391
Esophageal cancer: pneumo-64-MDCT.
Ulla M, Cavadas D, Muñoz I, Beskow A, Seehaus A, García-Mónaco R
Abdom Imaging 2010 Aug;35(4):383-9. Epub 2009 Jun 30 doi: 10.1007/s00261-009-9554-3. PMID: 19568806

Recent systematic reviews

Primary gastrointestinal anaplastic large cell lymphoma: A critical reappraisal with a systematic review of the world literature.
Mishra P, Patra S, Srinivasan A, Padhi S, Sable MN, Samal SC, Mohapatra S
J Cancer Res Ther 2021 Oct-Dec;17(6):1307-1313. doi: 10.4103/jcrt.JCRT_955_19. PMID: 34916358
Helicobacter pylori infection is associated with reduced risk of Barrett's esophagus: a meta-analysis and systematic review.
Du YL, Duan RQ, Duan LP
BMC Gastroenterol 2021 Dec 7;21(1):459. doi: 10.1186/s12876-021-02036-5. PMID: 34876031Free PMC Article
The relationship between metabolic syndrome and increased risk of Barrett's esophagus: an updated systematic review and meta-analysis.
Karimian M, Salamati M, Azami M
BMC Gastroenterol 2020 May 6;20(1):138. doi: 10.1186/s12876-020-01267-2. PMID: 32375671Free PMC Article
Prevention of esophageal stricture after endoscopic submucosal dissection: a systematic review and meta-analysis.
Oliveira JF, Moura EG, Bernardo WM, Ide E, Cheng S, Sulbaran M, Santos CM, Sakai P
Surg Endosc 2016 Jul;30(7):2779-91. Epub 2015 Oct 20 doi: 10.1007/s00464-015-4551-9. PMID: 26487197
Effectiveness of voice rehabilitation on vocalisation in postlaryngectomy patients: a systematic review.
Xi S
Int J Evid Based Healthc 2010 Dec;8(4):256-8. doi: 10.1111/j.1744-1609.2010.00177.x. PMID: 21091891

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...