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Ureaplasma Infections

MedGen UID:
43165
•Concept ID:
C0085395
•
Disease or Syndrome
Synonyms: Infection, Ureaplasma; Infections, Ureaplasma; Ureaplasma Infection

Definition

Infections with bacteria of the genus UREAPLASMA. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUreaplasma Infections

Professional guidelines

PubMed

Risk factors, management, and clinical outcomes of invasive Mycoplasma and Ureaplasma infections after lung transplantation.
Tam PCK, Hardie R, Alexander BD, Yarrington ME, Lee MJ, Polage CR, Messina JA, Maziarz EK, Saullo JL, Miller R, Wolfe CR, Arif S, Reynolds JM, Haney JC, Perfect JR, Baker AW
Am J Transplant 2024 Apr;24(4):641-652. Epub 2023 Aug 30 doi: 10.1016/j.ajt.2023.08.019. PMID: 37657654Free PMC Article

Recent clinical studies

Etiology

Maternal Ureaplasma exposure during pregnancy and the risk of preterm birth and BPD: a meta-analysis.
Xu YP, Hu JM, Huang YQ, Shi LP
Arch Gynecol Obstet 2022 Dec;306(6):1863-1872. Epub 2022 Mar 12 doi: 10.1007/s00404-022-06491-7. PMID: 35277749
Neonatal Mycoplasma and Ureaplasma Infections.
Chu A, de St Maurice A, Sim MS, Kallapur SG
Pediatr Ann 2020 Jul 1;49(7):e305-e312. doi: 10.3928/19382359-20200625-01. PMID: 32674168
Mycoplasma/Ureaplasma infection in pregnancy: to screen or not to screen.
Donders GGG, Ruban K, Bellen G, Petricevic L
J Perinat Med 2017 Jul 26;45(5):505-515. doi: 10.1515/jpm-2016-0111. PMID: 28099135
Mycoplasma and ureaplasma infection and male infertility: a systematic review and meta-analysis.
Huang C, Zhu HL, Xu KR, Wang SY, Fan LQ, Zhu WB
Andrology 2015 Sep;3(5):809-16. doi: 10.1111/andr.12078. PMID: 26311339
Ureaplasma and BPD.
Kallapur SG, Kramer BW, Jobe AH
Semin Perinatol 2013 Apr;37(2):94-101. doi: 10.1053/j.semperi.2013.01.005. PMID: 23582963Free PMC Article

Diagnosis

Perinatal Infections With Ureaplasma.
Stol K, Jans J, Ott de Bruin L, Unger W, van Rossum A
Pediatr Infect Dis J 2021 May 1;40(5S):S26-S30. doi: 10.1097/INF.0000000000002859. PMID: 34042907
Neonatal Mycoplasma and Ureaplasma Infections.
Chu A, de St Maurice A, Sim MS, Kallapur SG
Pediatr Ann 2020 Jul 1;49(7):e305-e312. doi: 10.3928/19382359-20200625-01. PMID: 32674168
Ureaplasma species and preterm birth: current perspectives.
Sprong KE, Mabenge M, Wright CA, Govender S
Crit Rev Microbiol 2020 Mar;46(2):169-181. Epub 2020 Mar 6 doi: 10.1080/1040841X.2020.1736986. PMID: 32141797
Ureaplasma: current perspectives.
Kokkayil P, Dhawan B
Indian J Med Microbiol 2015 Apr-Jun;33(2):205-14. doi: 10.4103/0255-0857.154850. PMID: 25865969
Ureaplasma urealyticum, Mycoplasma hominis and adverse pregnancy outcomes.
Capoccia R, Greub G, Baud D
Curr Opin Infect Dis 2013 Jun;26(3):231-40. doi: 10.1097/QCO.0b013e328360db58. PMID: 23587772

Therapy

Maternal Ureaplasma exposure during pregnancy and the risk of preterm birth and BPD: a meta-analysis.
Xu YP, Hu JM, Huang YQ, Shi LP
Arch Gynecol Obstet 2022 Dec;306(6):1863-1872. Epub 2022 Mar 12 doi: 10.1007/s00404-022-06491-7. PMID: 35277749
Neonatal Mycoplasma and Ureaplasma Infections.
Chu A, de St Maurice A, Sim MS, Kallapur SG
Pediatr Ann 2020 Jul 1;49(7):e305-e312. doi: 10.3928/19382359-20200625-01. PMID: 32674168
Ureaplasma species and preterm birth: current perspectives.
Sprong KE, Mabenge M, Wright CA, Govender S
Crit Rev Microbiol 2020 Mar;46(2):169-181. Epub 2020 Mar 6 doi: 10.1080/1040841X.2020.1736986. PMID: 32141797
Mycoplasma/Ureaplasma infection in pregnancy: to screen or not to screen.
Donders GGG, Ruban K, Bellen G, Petricevic L
J Perinat Med 2017 Jul 26;45(5):505-515. doi: 10.1515/jpm-2016-0111. PMID: 28099135
Ureaplasma and BPD.
Kallapur SG, Kramer BW, Jobe AH
Semin Perinatol 2013 Apr;37(2):94-101. doi: 10.1053/j.semperi.2013.01.005. PMID: 23582963Free PMC Article

Prognosis

Is there an association between recurrent spontaneous abortion and mycoplasma infection?
Yu J, Yu S, Zhu L, Sun X, Lu B, Li J, Hu Y, Li P
J Infect Dev Ctries 2022 Aug 30;16(8):1302-1307. doi: 10.3855/jidc.15134. PMID: 36099373
Optimum Detection of Ureaplasma in Premature Infants.
Brand MC, Mandy GT, Arora S, Castro EC, Gordon PS, Hagan JL, Zodin AL, Weisman LE
Pediatr Infect Dis J 2018 Dec;37(12):1294-1298. doi: 10.1097/INF.0000000000001994. PMID: 29634623
Ureaplasma urealyticum and Mycoplasma hominis infections and semen quality in 19,098 infertile men in China.
Huang C, Long X, Jing S, Fan L, Xu K, Wang S, Zhu W
World J Urol 2016 Jul;34(7):1039-44. Epub 2015 Nov 4 doi: 10.1007/s00345-015-1724-z. PMID: 26537883
Ureaplasma urealyticum and Ureaplasma parvum in women of reproductive age.
Hunjak B, Sabol I, Vojnović G, Fistonić I, Erceg AB, Peršić Z, Grce M
Arch Gynecol Obstet 2014 Feb;289(2):407-12. Epub 2013 Aug 4 doi: 10.1007/s00404-013-2980-z. PMID: 23912532
Serological response to Ureaplasma urealyticum in the neonate.
Quinn PA, Li HC, Th'ng C, Dunn M, Butany J
Clin Infect Dis 1993 Aug;17 Suppl 1:S136-43. doi: 10.1093/clinids/17.supplement_1.s136. PMID: 8399904

Clinical prediction guides

Ureaplasma and Prevotella colonization with Lactobacillus abundance during pregnancy facilitates term birth.
Park S, You YA, Kim YH, Kwon E, Ansari A, Kim SM, Lee G, Hur YM, Jung YJ, Kim K, Kim YJ
Sci Rep 2022 Jun 16;12(1):10148. doi: 10.1038/s41598-022-13871-1. PMID: 35710793Free PMC Article
Current understanding and treatment of intra-amniotic infection with Ureaplasma spp.
Tantengco OAG, Yanagihara I
J Obstet Gynaecol Res 2019 Sep;45(9):1796-1808. Epub 2019 Jul 16 doi: 10.1111/jog.14052. PMID: 31313469
Mycoplasma and ureaplasma infection and male infertility: a systematic review and meta-analysis.
Huang C, Zhu HL, Xu KR, Wang SY, Fan LQ, Zhu WB
Andrology 2015 Sep;3(5):809-16. doi: 10.1111/andr.12078. PMID: 26311339
Ureaplasma urealyticum, Mycoplasma hominis and adverse pregnancy outcomes.
Capoccia R, Greub G, Baud D
Curr Opin Infect Dis 2013 Jun;26(3):231-40. doi: 10.1097/QCO.0b013e328360db58. PMID: 23587772
Congenital and opportunistic infections: Ureaplasma species and Mycoplasma hominis.
Waites KB, Schelonka RL, Xiao L, Grigsby PL, Novy MJ
Semin Fetal Neonatal Med 2009 Aug;14(4):190-9. Epub 2008 Dec 23 doi: 10.1016/j.siny.2008.11.009. PMID: 19109084

Recent systematic reviews

Trends of fluoroquinolones resistance in Mycoplasma and Ureaplasma urogenital isolates: Systematic review and meta-analysis.
Wu Y, Majidzadeh N, Li Y, Zafar Shakourzadeh M, Hajilari S, Kouhsari E, Azizian K
J Glob Antimicrob Resist 2024 Mar;36:13-25. Epub 2023 Nov 26 doi: 10.1016/j.jgar.2023.11.007. PMID: 38016593
Global analysis on the mutations associated with multidrug-resistant urogenital mycoplasmas and ureaplasmas infection: a systematic review and meta-analysis.
Abavisani M, Keikha M
Ann Clin Microbiol Antimicrob 2023 Aug 10;22(1):70. doi: 10.1186/s12941-023-00627-6. PMID: 37563660Free PMC Article
Mycoplasma and ureaplasma infection and male infertility: a systematic review and meta-analysis.
Huang C, Zhu HL, Xu KR, Wang SY, Fan LQ, Zhu WB
Andrology 2015 Sep;3(5):809-16. doi: 10.1111/andr.12078. PMID: 26311339
Are Ureaplasma spp. a cause of nongonococcal urethritis? A systematic review and meta-analysis.
Zhang N, Wang R, Li X, Liu X, Tang Z, Liu Y
PLoS One 2014;9(12):e113771. Epub 2014 Dec 2 doi: 10.1371/journal.pone.0113771. PMID: 25463970Free PMC Article
Antibiotics for ureaplasma in the vagina in pregnancy.
Raynes Greenow CH, Roberts CL, Bell JC, Peat B, Gilbert GL, Parker S
Cochrane Database Syst Rev 2011 Sep 7;2011(9):CD003767. doi: 10.1002/14651858.CD003767.pub3. PMID: 21901685Free PMC Article

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