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Spotted fevers

MedGen UID:
11567
•Concept ID:
C0038041
•
Disease or Syndrome
Synonyms: Fever, Spotted; Fevers, Spotted; Spotted Fever; Spotted Fever Group Rickettsioses; Spotted Fever Group Rickettsiosis; Spotted Fevers
SNOMED CT: Spotted fever group rickettsial disease (186771002); Spotted fevers (186771002)

Definition

A group of arthropod-borne diseases caused by spotted fever bio-group members of RICKETTSIA. They are characterized by fever, headache, and petechial (spotted) rash. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSpotted fevers

Professional guidelines

PubMed

Diagnosis and treatment of tick infestation and tick-borne diseases with cutaneous manifestations.
Dana AN
Dermatol Ther 2009 Jul-Aug;22(4):293-326. doi: 10.1111/j.1529-8019.2009.01244.x. PMID: 19580576
Treatment and prevention of rickettsial and ehrlichial infections.
Maender JL, Tyring SK
Dermatol Ther 2004;17(6):499-504. doi: 10.1111/j.1396-0296.2004.04052.x. PMID: 15571498
Antibiotic susceptibility of rickettsia and treatment of rickettsioses.
Raoult D
Eur J Epidemiol 1989 Dec;5(4):432-5. doi: 10.1007/BF00140135. PMID: 2606171

Recent clinical studies

Etiology

Tick-borne rickettsioses in Europe – a review.
Borawski K, Dunaj J, Pancewicz S, Król M, Czupryna P, Moniuszko-Malinowska A
Przegl Epidemiol 2019;73(4):523-530. doi: 10.32394/pe.73.49. PMID: 32237701
Typhus and the spotted fevers.
Buchanan R
Br J Hosp Med (Lond) 2018 Oct 2;79(10):C146-C149. doi: 10.12968/hmed.2018.79.10.C146. PMID: 30290740
Rickettsioses and Q fever in travelers (2004-2013).
Delord M, Socolovschi C, Parola P
Travel Med Infect Dis 2014 Sep-Oct;12(5):443-58. Epub 2014 Sep 16 doi: 10.1016/j.tmaid.2014.08.006. PMID: 25262433
Rickettsial infections in the tropics and in the traveler.
Blanton LS
Curr Opin Infect Dis 2013 Oct;26(5):435-40. doi: 10.1097/QCO.0b013e328363811b. PMID: 23842049
Dermatoses from ticks.
McGinley-Smith DE, Tsao SS
J Am Acad Dermatol 2003 Sep;49(3):363-92; quiz 393-6. doi: 10.1067/s0190-9622(03)01868-1. PMID: 12963900

Diagnosis

Tick-borne rickettsioses in Europe – a review.
Borawski K, Dunaj J, Pancewicz S, Król M, Czupryna P, Moniuszko-Malinowska A
Przegl Epidemiol 2019;73(4):523-530. doi: 10.32394/pe.73.49. PMID: 32237701
Typhus and the spotted fevers.
Buchanan R
Br J Hosp Med (Lond) 2018 Oct 2;79(10):C146-C149. doi: 10.12968/hmed.2018.79.10.C146. PMID: 30290740
Rickettsioses and Q fever in travelers (2004-2013).
Delord M, Socolovschi C, Parola P
Travel Med Infect Dis 2014 Sep-Oct;12(5):443-58. Epub 2014 Sep 16 doi: 10.1016/j.tmaid.2014.08.006. PMID: 25262433
Diagnosis and treatment of tick infestation and tick-borne diseases with cutaneous manifestations.
Dana AN
Dermatol Ther 2009 Jul-Aug;22(4):293-326. doi: 10.1111/j.1529-8019.2009.01244.x. PMID: 19580576
Dermatoses from ticks.
McGinley-Smith DE, Tsao SS
J Am Acad Dermatol 2003 Sep;49(3):363-92; quiz 393-6. doi: 10.1067/s0190-9622(03)01868-1. PMID: 12963900

Therapy

Tick-borne rickettsioses in Europe – a review.
Borawski K, Dunaj J, Pancewicz S, Król M, Czupryna P, Moniuszko-Malinowska A
Przegl Epidemiol 2019;73(4):523-530. doi: 10.32394/pe.73.49. PMID: 32237701
Spotted fever group rickettsioses in Himachal Pradesh.
Mahajan SK, Kashyap R, Sankhyan N, Sharma V, Rolain JM, Prasher BS, Raoult D
J Assoc Physicians India 2007 Dec;55:868-70. PMID: 18405137
Treatment and prevention of rickettsial and ehrlichial infections.
Maender JL, Tyring SK
Dermatol Ther 2004;17(6):499-504. doi: 10.1111/j.1396-0296.2004.04052.x. PMID: 15571498
Mediterranean spotted fever in pregnancy.
Cohen J, Lasri Y, Landau Z
Scand J Infect Dis 1999;31(2):202-3. doi: 10.1080/003655499750006290. PMID: 10447334
Antibiotic susceptibility of rickettsia and treatment of rickettsioses.
Raoult D
Eur J Epidemiol 1989 Dec;5(4):432-5. doi: 10.1007/BF00140135. PMID: 2606171

Prognosis

Increasing Incidence of Spotted Fever Group Rickettsioses in the United States, 2010-2018.
Bishop A, Borski J, Wang HH, Donaldson TG, Michalk A, Montgomery A, Heldman S, Mogg M, Derouen Z, Grant WE, Teel PD
Vector Borne Zoonotic Dis 2022 Sep;22(9):491-497. Epub 2022 Aug 26 doi: 10.1089/vbz.2022.0021. PMID: 36037000
Fatal case of spotted fever in a patient from Northeastern Brazil.
Oliveira SV, Costa RMF, Ferreira G, Pereira SVC, Amorim M, Monteiro MFM, Alves LC, Gazeta GS
Rev Inst Med Trop Sao Paulo 2018;60:e21. Epub 2018 May 28 doi: 10.1590/s1678-9946201860021. PMID: 29846472Free PMC Article
Dermatoses from ticks.
McGinley-Smith DE, Tsao SS
J Am Acad Dermatol 2003 Sep;49(3):363-92; quiz 393-6. doi: 10.1067/s0190-9622(03)01868-1. PMID: 12963900
Hemorrhagic fever with renal syndrome.
Lee HW, van der Groen G
Prog Med Virol 1989;36:62-102. PMID: 2573914

Clinical prediction guides

Rickettsia parkeri in free-ranging wild canids from Brazilian Pampa.
Dall'Agnol B, Souza UA, Weck B, Trigo TC, Jardim MMA, Costa FB, Labruna MB, Peters FB, Favarini MO, Mazim FD, Ferreira CAS, Reck J
Transbound Emerg Dis 2018 Apr;65(2):e224-e230. Epub 2017 Nov 8 doi: 10.1111/tbed.12743. PMID: 29119703

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