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Cystic Endometrial Hyperplasia

MedGen UID:
1206
•Concept ID:
C0010673
•
Neoplastic Process
Synonyms: Endometrial cystic hyperplasia; Swiss cheese hyperplasia of the endometrium
SNOMED CT: Endometrial cystic hyperplasia (198321009); Swiss cheese hyperplasia of the endometrium (198321009)

Definition

Benign endometrial hyperplasia characterized by the presence of cystically dilated glands. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCystic Endometrial Hyperplasia

Professional guidelines

PubMed

Medical treatment for adenomyosis and/or adenomyoma.
Tsui KH, Lee WL, Chen CY, Sheu BC, Yen MS, Chang TC, Wang PH
Taiwan J Obstet Gynecol 2014 Dec;53(4):459-65. doi: 10.1016/j.tjog.2014.04.024. PMID: 25510683
Clinical utility of progesterone receptor modulators and their effect on the endometrium.
Spitz IM
Curr Opin Obstet Gynecol 2009 Aug;21(4):318-24. doi: 10.1097/GCO.0b013e32832e07e8. PMID: 19602929
Treatment of endometrial hyperplasia with levonorgestrel releasing intrauterine devices.
Perino A, Quartararo P, Catinella E, Genova G, Cittadini E
Acta Eur Fertil 1987 Mar-Apr;18(2):137-40. PMID: 3115027

Recent clinical studies

Etiology

Renal biomarkers, clinical parameters, and renal Doppler velocimetry in bitches with cystic endometrial hyperplasia-pyometra complex.
Dos Santos Silva LA, Trautwein LGC, Hidalgo MMT, de Almeida ABM, Greghi JR, Sambatti NR, Silva VW, da Costa Flaiban KKM, Martins MIM
Reprod Domest Anim 2024 Jan;59(1):e14518. doi: 10.1111/rda.14518. PMID: 38268215
Cystic endometrial hyperplasia-pyometra syndrome impairs the preantral follicle reserve in domestic bitches (Canis familiaris).
Camozzi MGM, Saturnino KC, Machado MRF, Gastal GDA, Moreira CN, Alves BG
Reprod Biol 2023 Dec;23(4):100813. Epub 2023 Oct 11 doi: 10.1016/j.repbio.2023.100813. PMID: 37832392
Elastosonographic evaluation of endometrium in women using tamoxifen for breast cancer.
Gultekin IB, Imamoglu GI, Gultekin S, Yilmaz EA, Yilmaz Z, Alkan A, Kucukozkan T
Niger J Clin Pract 2019 Jan;22(1):92-100. doi: 10.4103/njcp.njcp_387_16. PMID: 30666026
Proliferative and apoptotic changes in the healthy canine endometrium and in cystic endometrial hyperplasia.
Reusche N, Beineke A, Urhausen C, Beyerbach M, Schmicke M, Kramer S, Günzel-Apel AR
Theriogenology 2018 Jul 1;114:14-24. Epub 2018 Mar 15 doi: 10.1016/j.theriogenology.2018.03.018. PMID: 29574305
Cytotoxic Escherichia coli strains encoding colibactin colonize laboratory mice.
García A, Mannion A, Feng Y, Madden CM, Bakthavatchalu V, Shen Z, Ge Z, Fox JG
Microbes Infect 2016 Dec;18(12):777-786. Epub 2016 Jul 30 doi: 10.1016/j.micinf.2016.07.005. PMID: 27480057Free PMC Article

Diagnosis

Renal biomarkers, clinical parameters, and renal Doppler velocimetry in bitches with cystic endometrial hyperplasia-pyometra complex.
Dos Santos Silva LA, Trautwein LGC, Hidalgo MMT, de Almeida ABM, Greghi JR, Sambatti NR, Silva VW, da Costa Flaiban KKM, Martins MIM
Reprod Domest Anim 2024 Jan;59(1):e14518. doi: 10.1111/rda.14518. PMID: 38268215
Cystic endometrial hyperplasia-pyometra syndrome impairs the preantral follicle reserve in domestic bitches (Canis familiaris).
Camozzi MGM, Saturnino KC, Machado MRF, Gastal GDA, Moreira CN, Alves BG
Reprod Biol 2023 Dec;23(4):100813. Epub 2023 Oct 11 doi: 10.1016/j.repbio.2023.100813. PMID: 37832392
Ovarian Cysts in the Bitch: An Update.
Sasidharan JK, Patra MK, Singh LK, Saxena AC, De UK, Singh V, Mathesh K, Kumar H, Krishnaswamy N
Top Companion Anim Med 2021 Jun;43:100511. Epub 2021 Jan 9 doi: 10.1016/j.tcam.2021.100511. PMID: 33434678
Elastosonographic evaluation of endometrium in women using tamoxifen for breast cancer.
Gultekin IB, Imamoglu GI, Gultekin S, Yilmaz EA, Yilmaz Z, Alkan A, Kucukozkan T
Niger J Clin Pract 2019 Jan;22(1):92-100. doi: 10.4103/njcp.njcp_387_16. PMID: 30666026
An intrauterine progesterone contraceptive system (52 mg) used in pre- and peri-menopausal patients with endometrial hyperplasia.
Volpe A, Botticelli A, Abrate M, Dalla Vecchia E, Mantovani M, Carani C, Grasso A, Mazza V, Di Renzo GC
Maturitas 1982 Apr;4(1):73-9. doi: 10.1016/0378-5122(82)90022-6. PMID: 6285154

Therapy

Elastosonographic evaluation of endometrium in women using tamoxifen for breast cancer.
Gultekin IB, Imamoglu GI, Gultekin S, Yilmaz EA, Yilmaz Z, Alkan A, Kucukozkan T
Niger J Clin Pract 2019 Jan;22(1):92-100. doi: 10.4103/njcp.njcp_387_16. PMID: 30666026
An intrauterine progesterone contraceptive system (52 mg) used in pre- and peri-menopausal patients with endometrial hyperplasia.
Volpe A, Botticelli A, Abrate M, Dalla Vecchia E, Mantovani M, Carani C, Grasso A, Mazza V, Di Renzo GC
Maturitas 1982 Apr;4(1):73-9. doi: 10.1016/0378-5122(82)90022-6. PMID: 6285154

Prognosis

Elastosonographic evaluation of endometrium in women using tamoxifen for breast cancer.
Gultekin IB, Imamoglu GI, Gultekin S, Yilmaz EA, Yilmaz Z, Alkan A, Kucukozkan T
Niger J Clin Pract 2019 Jan;22(1):92-100. doi: 10.4103/njcp.njcp_387_16. PMID: 30666026

Clinical prediction guides

Elastosonographic evaluation of endometrium in women using tamoxifen for breast cancer.
Gultekin IB, Imamoglu GI, Gultekin S, Yilmaz EA, Yilmaz Z, Alkan A, Kucukozkan T
Niger J Clin Pract 2019 Jan;22(1):92-100. doi: 10.4103/njcp.njcp_387_16. PMID: 30666026
Spontaneous Reproductive Tract Lesions in Aged Captive Chimpanzees.
Chaffee BK, Beck AP, Owston MA, Kumar S, Baze WB, Magden ER, Dick EJ Jr, Lammey M, Abee CR
Vet Pathol 2016 Mar;53(2):425-35. Epub 2016 Jan 28 doi: 10.1177/0300985815620654. PMID: 26823448Free PMC Article

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