U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Coronary heart disease

MedGen UID:
3624
•Concept ID:
C0010068
•
Disease or Syndrome
Synonyms: Coronary Disease; Coronary Diseases; Coronary Heart Disease; Coronary Heart Diseases; Disease, Coronary; Disease, Coronary Heart; Diseases, Coronary; Diseases, Coronary Heart; Heart Disease, Coronary; Heart Diseases, Coronary
SNOMED CT: CHD - Coronary heart disease (53741008); Coronary heart disease (53741008)

Definition

An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. [from MeSH]

Professional guidelines

PubMed

2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.
Joglar JA, Chung MK, Armbruster AL, Benjamin EJ, Chyou JY, Cronin EM, Deswal A, Eckhardt LL, Goldberger ZD, Gopinathannair R, Gorenek B, Hess PL, Hlatky M, Hogan G, Ibeh C, Indik JH, Kido K, Kusumoto F, Link MS, Linta KT, Marcus GM, McCarthy PM, Patel N, Patton KK, Perez MV, Piccini JP, Russo AM, Sanders P, Streur MM, Thomas KL, Times S, Tisdale JE, Valente AM, Van Wagoner DR; Peer Review Committee Members
Circulation 2024 Jan 2;149(1):e1-e156. Epub 2023 Nov 30 doi: 10.1161/CIR.0000000000001193. PMID: 38033089Free PMC Article
The 2022 hormone therapy position statement of The North American Menopause Society.
“The 2022 Hormone Therapy Position Statement of The North American Menopause Society” Advisory Panel
Menopause 2022 Jul 1;29(7):767-794. doi: 10.1097/GME.0000000000002028. PMID: 35797481
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.
Arnett DK, Blumenthal RS, Albert MA, Buroker AB, Goldberger ZD, Hahn EJ, Himmelfarb CD, Khera A, Lloyd-Jones D, McEvoy JW, Michos ED, Miedema MD, Muñoz D, Smith SC Jr, Virani SS, Williams KA Sr, Yeboah J, Ziaeian B
Circulation 2019 Sep 10;140(11):e596-e646. Epub 2019 Mar 17 doi: 10.1161/CIR.0000000000000678. PMID: 30879355Free PMC Article

Recent clinical studies

Etiology

Direct medical costs of cardiovascular diseases: Do cost components vary according to sex and age?
Gilbert-Ouimet M, Sultan-Taïeb H, Ben Charif A, Brisson C, Lavigne-Robichaud M, Milot A, Trudel X, Demers É, Guertin JR
PLoS One 2024;19(10):e0311599. Epub 2024 Oct 10 doi: 10.1371/journal.pone.0311599. PMID: 39388420Free PMC Article
Effect of case management based on Omaha system on clinical symptoms and quality of life of coronary heart disease patients after percutaneous coronary intervention.
Wu L, Liu X, Tang X, Qi X, Song J, Huang W, You T, Mei B, Xiong H
Medicine (Baltimore) 2024 Jun 28;103(26):e38553. doi: 10.1097/MD.0000000000038553. PMID: 38941436Free PMC Article
Aspirin Use and Risk of Alzheimer's Disease: A 2-Sample Mendelian Randomization Study.
Ding P, Gorenflo MP, Zhu X, Xu R
J Alzheimers Dis 2023;92(3):989-1000. doi: 10.3233/JAD-220787. PMID: 36846997Free PMC Article
Sex Hormone-Binding Globulin and Risk of Coronary Heart Disease in Men and Women.
Li J, Zheng L, Chan KHK, Zou X, Zhang J, Liu J, Zhong Q, Madsen TE, Wu WC, Manson JE, Yu X, Liu S
Clin Chem 2023 Apr 3;69(4):374-385. doi: 10.1093/clinchem/hvac209. PMID: 36702572
Added Sugar, Sugar-Sweetened Beverages, and Artificially Sweetened Beverages and Risk of Cardiovascular Disease: Findings from the Women's Health Initiative and a Network Meta-Analysis of Prospective Studies.
Yang B, Glenn AJ, Liu Q, Madsen T, Allison MA, Shikany JM, Manson JE, Chan KHK, Wu WC, Li J, Liu S, Lo K
Nutrients 2022 Oct 11;14(20) doi: 10.3390/nu14204226. PMID: 36296910Free PMC Article

Diagnosis

Environmental chemical exposures and a machine learning-based model for predicting hypertension in NHANES 2003-2016.
Guo K, Ni W, Du L, Zhou Y, Cheng L, Zhou H
BMC Cardiovasc Disord 2024 Oct 9;24(1):544. doi: 10.1186/s12872-024-04216-z. PMID: 39385080Free PMC Article

Therapy

Emerging Evidence on Coronary Heart Disease Screening in Kidney and Liver Transplantation Candidates: A Scientific Statement From the American Heart Association: Endorsed by the American Society of Transplantation.
Cheng XS, VanWagner LB, Costa SP, Axelrod DA, Bangalore S, Norman SP, Herzog CA, Lentine KL; American Heart Association Council on the Kidney in Cardiovascular Disease and Council on Cardiovascular Radiology and Intervention
Circulation 2022 Nov 22;146(21):e299-e324. Epub 2022 Oct 17 doi: 10.1161/CIR.0000000000001104. PMID: 36252095Free PMC Article
Arterial hypertension - Clinical trials update 2021.
Al Ghorani H, Götzinger F, Böhm M, Mahfoud F
Nutr Metab Cardiovasc Dis 2022 Jan;32(1):21-31. Epub 2021 Sep 16 doi: 10.1016/j.numecd.2021.09.007. PMID: 34690044Free PMC Article
Improving Medication Adherence in Coronary Heart Disease.
Zullig LL, Ramos K, Bosworth HB
Curr Cardiol Rep 2017 Sep 22;19(11):113. doi: 10.1007/s11886-017-0918-y. PMID: 28940020
Observational data for comparative effectiveness research: an emulation of randomised trials of statins and primary prevention of coronary heart disease.
Danaei G, Rodríguez LA, Cantero OF, Logan R, Hernán MA
Stat Methods Med Res 2013 Feb;22(1):70-96. Epub 2011 Oct 19 doi: 10.1177/0962280211403603. PMID: 22016461Free PMC Article
Coronary heart disease.
American College of Obstetricians and Gynecologists Women's Health Care Physicians
Obstet Gynecol 2004 Oct;104(4 Suppl):41S-48S. doi: 10.1097/01.AOG.0000138802.06080.43. PMID: 15458932

Prognosis

Social inequalities in multimorbidity, frailty, disability, and transitions to mortality: a 24-year follow-up of the Whitehall II cohort study.
Dugravot A, Fayosse A, Dumurgier J, Bouillon K, Rayana TB, Schnitzler A, Kivimaki M, Sabia S, Singh-Manoux A
Lancet Public Health 2020 Jan;5(1):e42-e50. Epub 2019 Dec 16 doi: 10.1016/S2468-2667(19)30226-9. PMID: 31837974Free PMC Article
Association of Blood Pressure Lowering With Mortality and Cardiovascular Disease Across Blood Pressure Levels: A Systematic Review and Meta-analysis.
Brunström M, Carlberg B
JAMA Intern Med 2018 Jan 1;178(1):28-36. doi: 10.1001/jamainternmed.2017.6015. PMID: 29131895Free PMC Article
Potential health hazards of eating red meat.
Wolk A
J Intern Med 2017 Feb;281(2):106-122. Epub 2016 Sep 6 doi: 10.1111/joim.12543. PMID: 27597529
Association between sauna bathing and fatal cardiovascular and all-cause mortality events.
Laukkanen T, Khan H, Zaccardi F, Laukkanen JA
JAMA Intern Med 2015 Apr;175(4):542-8. doi: 10.1001/jamainternmed.2014.8187. PMID: 25705824
Association of alcohol consumption with selected cardiovascular disease outcomes: a systematic review and meta-analysis.
Ronksley PE, Brien SE, Turner BJ, Mukamal KJ, Ghali WA
BMJ 2011 Feb 22;342:d671. doi: 10.1136/bmj.d671. PMID: 21343207Free PMC Article

Clinical prediction guides

Chronic inflammatory diseases and coronary heart disease: Insights from cardiovascular CT.
Patel NH, Dey AK, Sorokin AV, Teklu M, Petrole R, Zhou W, Mehta NN
J Cardiovasc Comput Tomogr 2022 Jan-Feb;16(1):7-18. Epub 2021 Jun 24 doi: 10.1016/j.jcct.2021.06.003. PMID: 34226164
The atherosclerosis burden score.
Koulouri A, Darioli R, Dine Qanadli S, Katz E, Eeckhout E, Mazzolai L, Depairon M
Vasa 2021 Jul;50(4):280-285. Epub 2021 Apr 1 doi: 10.1024/0301-1526/a000949. PMID: 33789435
Cardiac Imaging for Coronary Heart Disease Risk Stratification in Chronic Kidney Disease.
Dilsizian V, Gewirtz H, Marwick TH, Kwong RY, Raggi P, Al-Mallah MH, Herzog CA
JACC Cardiovasc Imaging 2021 Mar;14(3):669-682. Epub 2020 Aug 19 doi: 10.1016/j.jcmg.2020.05.035. PMID: 32828780
Cardiovascular Event Prediction by Machine Learning: The Multi-Ethnic Study of Atherosclerosis.
Ambale-Venkatesh B, Yang X, Wu CO, Liu K, Hundley WG, McClelland R, Gomes AS, Folsom AR, Shea S, Guallar E, Bluemke DA, Lima JAC
Circ Res 2017 Oct 13;121(9):1092-1101. Epub 2017 Aug 9 doi: 10.1161/CIRCRESAHA.117.311312. PMID: 28794054Free PMC Article
Prediction models for cardiovascular disease risk in the general population: systematic review.
Damen JA, Hooft L, Schuit E, Debray TP, Collins GS, Tzoulaki I, Lassale CM, Siontis GC, Chiocchia V, Roberts C, Schlüssel MM, Gerry S, Black JA, Heus P, van der Schouw YT, Peelen LM, Moons KG
BMJ 2016 May 16;353:i2416. doi: 10.1136/bmj.i2416. PMID: 27184143Free PMC Article

Recent systematic reviews

Relationship between Hyperlipidemia, Cardiovascular Disease and Stroke: A Systematic Review.
Alloubani A, Nimer R, Samara R
Curr Cardiol Rev 2021;17(6):e051121189015. doi: 10.2174/1573403X16999201210200342. PMID: 33305711Free PMC Article
Prevalence of cardiovascular disease in type 2 diabetes: a systematic literature review of scientific evidence from across the world in 2007-2017.
Einarson TR, Acs A, Ludwig C, Panton UH
Cardiovasc Diabetol 2018 Jun 8;17(1):83. doi: 10.1186/s12933-018-0728-6. PMID: 29884191Free PMC Article
Loneliness and social isolation as risk factors for coronary heart disease and stroke: systematic review and meta-analysis of longitudinal observational studies.
Valtorta NK, Kanaan M, Gilbody S, Ronzi S, Hanratty B
Heart 2016 Jul 1;102(13):1009-16. Epub 2016 Apr 18 doi: 10.1136/heartjnl-2015-308790. PMID: 27091846Free PMC Article
Exercise-Based Cardiac Rehabilitation for Coronary Heart Disease: Cochrane Systematic Review and Meta-Analysis.
Anderson L, Oldridge N, Thompson DR, Zwisler AD, Rees K, Martin N, Taylor RS
J Am Coll Cardiol 2016 Jan 5;67(1):1-12. doi: 10.1016/j.jacc.2015.10.044. PMID: 26764059
Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis.
Ettehad D, Emdin CA, Kiran A, Anderson SG, Callender T, Emberson J, Chalmers J, Rodgers A, Rahimi K
Lancet 2016 Mar 5;387(10022):957-967. Epub 2015 Dec 24 doi: 10.1016/S0140-6736(15)01225-8. PMID: 26724178

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • ClinVar
      Related medical variations
    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...