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Items: 4

  • The following terms were not found in MedGen: 5E, opmusic, notecapital, Cyrillicopop.
1.

Basal-like breast carcinoma

A biologic subset of breast carcinoma defined by high expression of genes characteristic of basal epithelial cells, including KRT5 and KRT17, annexin 8, CX3CL1, and TRIM29, and usually by lack of expression of the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). It is the most common subtype of breast cancer associated with BRCA1 mutations, and is associated with a poor prognosis. [from NCI]

MedGen UID:
770987
Concept ID:
C3642347
Neoplastic Process
2.

Luminal A breast carcinoma

A biologic subset of breast carcinoma defined by high expression of genes characteristic of luminal epithelial cells, including estrogen receptor (ER), estrogen regulated protein LIV-1, and the transcription factors hepatocyte nuclear factor 3, HNF3A, XBP1, and GATA 3. This subtype of breast cancer is associated with a good prognosis. [from NCI]

MedGen UID:
770985
Concept ID:
C3642345
Neoplastic Process
3.

HER2 positive breast carcinoma

A biologic subset of breast carcinoma defined by high expression of HER2, GRB7, and TRAP100, and by lack of expression of estrogen receptor (ER). [from NCI]

MedGen UID:
743175
Concept ID:
C1960398
Neoplastic Process
4.

Luminal B breast carcinoma

A biologic subset of breast carcinoma defined by low to moderate expression of genes characteristic of luminal epithelial cells including estrogen receptor (ER), and high expression of GGH, LAPTM4B, and CCNE1. This subtype of breast cancer is associated with a good prognosis, although not as favorable as the luminal A subtype. [from NCI]

MedGen UID:
770986
Concept ID:
C3642346
Neoplastic Process
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