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Vulvar Merkel Cell Carcinoma

MedGen UID:
925535
Concept ID:
C4288003
Neoplastic Process

Definition

A Merkel cell carcinoma that arises from the vulva. It usually presents as a cutaneous nodular lesion. Most small cell neuroendocrine carcinomas of the vulva are Merkel cell carcinomas. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVulvar Merkel Cell Carcinoma

Professional guidelines

PubMed

Cohen JG, Chan JK, Kapp DS
Curr Opin Oncol 2012 Sep;24(5):572-9. doi: 10.1097/CCO.0b013e3283565ed6. PMID: 22820410
Gipponi M
Minerva Chir 2005 Aug;60(4):217-33. PMID: 16166921

Recent clinical studies

Etiology

Chen PP, Ramalingam P, Alvarado-Cabrero I, Euscher ED, Nagarajan P, Lawson BC, Malpica A
Am J Surg Pathol 2021 Mar 1;45(3):304-316. doi: 10.1097/PAS.0000000000001558. PMID: 32826525
Haley CT, Mui UN, Vangipuram R, Rady PL, Tyring SK
J Am Acad Dermatol 2019 Jul;81(1):1-21. Epub 2018 Nov 28 doi: 10.1016/j.jaad.2018.09.062. PMID: 30502418
Cañueto J, Román-Curto C
Actas Dermosifiliogr 2017 Nov;108(9):818-826. Epub 2017 Jul 18 doi: 10.1016/j.ad.2017.05.012. PMID: 28732551
Fratini M, Di Bonito P, La Rosa G
Food Environ Virol 2014 Mar;6(1):1-12. Epub 2013 Nov 30 doi: 10.1007/s12560-013-9134-0. PMID: 24293168
Cohen JG, Chan JK, Kapp DS
Curr Opin Oncol 2012 Sep;24(5):572-9. doi: 10.1097/CCO.0b013e3283565ed6. PMID: 22820410

Diagnosis

Hirakawa T, Yano M, Nishida H, Sato S, Nasu K
BMC Endocr Disord 2022 Mar 29;22(1):81. doi: 10.1186/s12902-022-00987-8. PMID: 35351092Free PMC Article
Chen PP, Ramalingam P, Alvarado-Cabrero I, Euscher ED, Nagarajan P, Lawson BC, Malpica A
Am J Surg Pathol 2021 Mar 1;45(3):304-316. doi: 10.1097/PAS.0000000000001558. PMID: 32826525
Haley CT, Mui UN, Vangipuram R, Rady PL, Tyring SK
J Am Acad Dermatol 2019 Jul;81(1):1-21. Epub 2018 Nov 28 doi: 10.1016/j.jaad.2018.09.062. PMID: 30502418
Cohen JG, Chan JK, Kapp DS
Curr Opin Oncol 2012 Sep;24(5):572-9. doi: 10.1097/CCO.0b013e3283565ed6. PMID: 22820410
Finan MA, Barre G
Best Pract Res Clin Obstet Gynaecol 2003 Aug;17(4):609-33. doi: 10.1016/s1521-6934(03)00039-7. PMID: 12965135

Therapy

Cohen JG, Chan JK, Kapp DS
Curr Opin Oncol 2012 Sep;24(5):572-9. doi: 10.1097/CCO.0b013e3283565ed6. PMID: 22820410
Boldorini R, Riboni F, Cristina S, Allegrini S, Valentini S, Muscarà M, Ruspa G
Pathol Res Pract 2010 Jul 15;206(7):476-9. Epub 2009 Aug 4 doi: 10.1016/j.prp.2009.07.006. PMID: 19656640

Prognosis

Chen PP, Ramalingam P, Alvarado-Cabrero I, Euscher ED, Nagarajan P, Lawson BC, Malpica A
Am J Surg Pathol 2021 Mar 1;45(3):304-316. doi: 10.1097/PAS.0000000000001558. PMID: 32826525
Haley CT, Mui UN, Vangipuram R, Rady PL, Tyring SK
J Am Acad Dermatol 2019 Jul;81(1):1-21. Epub 2018 Nov 28 doi: 10.1016/j.jaad.2018.09.062. PMID: 30502418
Cohen JG, Chan JK, Kapp DS
Curr Opin Oncol 2012 Sep;24(5):572-9. doi: 10.1097/CCO.0b013e3283565ed6. PMID: 22820410
Albores-Saavedra J, Batich K, Chable-Montero F, Sagy N, Schwartz AM, Henson DE
J Cutan Pathol 2010 Jan;37(1):20-7. Epub 2009 Jul 23 doi: 10.1111/j.1600-0560.2009.01370.x. PMID: 19638070
Gil-Moreno A, Garcia-Jiménez A, González-Bosquet J, Esteller M, Castellví-Vives J, Martínez Palones JM, Xercavins J
Gynecol Oncol 1997 Mar;64(3):526-32. doi: 10.1006/gyno.1996.4575. PMID: 9062165

Clinical prediction guides

De Wispelaere N, Rico SD, Bauer M, Luebke AM, Kluth M, Büscheck F, Hube-Magg C, Höflmayer D, Gorbokon N, Weidemann S, Möller K, Fraune C, Bernreuther C, Simon R, Kähler C, Menz A, Hinsch A, Jacobsen F, Lebok P, Clauditz T, Sauter G, Uhlig R, Wilczak W, Steurer S, Burandt E, Krech R, Dum D, Krech T, Marx A, Minner S
PLoS One 2022;17(7):e0262877. Epub 2022 Jul 21 doi: 10.1371/journal.pone.0262877. PMID: 35862385Free PMC Article
Chen PP, Ramalingam P, Alvarado-Cabrero I, Euscher ED, Nagarajan P, Lawson BC, Malpica A
Am J Surg Pathol 2021 Mar 1;45(3):304-316. doi: 10.1097/PAS.0000000000001558. PMID: 32826525
Fratini M, Di Bonito P, La Rosa G
Food Environ Virol 2014 Mar;6(1):1-12. Epub 2013 Nov 30 doi: 10.1007/s12560-013-9134-0. PMID: 24293168
Albores-Saavedra J, Batich K, Chable-Montero F, Sagy N, Schwartz AM, Henson DE
J Cutan Pathol 2010 Jan;37(1):20-7. Epub 2009 Jul 23 doi: 10.1111/j.1600-0560.2009.01370.x. PMID: 19638070
Gipponi M
Minerva Chir 2005 Aug;60(4):217-33. PMID: 16166921

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