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APUdoma

MedGen UID:
379
•Concept ID:
C0003650
•
Neoplastic Process
Synonym: APUD (amine precursor uptake and decarboxylation)
SNOMED CT: Apudoma (74926005); Apudoma (253008000)
 
HPO: HP:0040192

Definition

An endocrine tumor arising from an APUD cell. [from HPO]

Professional guidelines

PubMed

Use of octreotide in the treatment of digestive neuroendocrine tumours. Seven year experience in 20 cases including 9 cases of metastatic midgut carcinoid and 5 cases of metastatic gastrinoma.
Fiasse R, Pauwels S, Rahier J, Jamar F, Ketelslegers JM, Hassoun A, de Longueville M
Acta Gastroenterol Belg 1993 May-Aug;56(3-4):279-91. PMID: 8266771
Carboplatin in the treatment of metastatic carcinoid tumours and paraganglioma: a phase II study.
Jodrell DI, Smith IE
Cancer Chemother Pharmacol 1990;26(1):62-4. doi: 10.1007/BF02940296. PMID: 1691051

Recent clinical studies

Etiology

Neuroendocrine tumours--analysis of own material--a nine--year retrospective study.
Kaliszewski K, Bednarz W, Łukieńczuk T, Balcerzak W, Kaliszewska M, Dawiskiba J
Hepatogastroenterology 2010 Mar-Apr;57(98):236-41. PMID: 20583420
Pancreatic endocrine tumors: recent advances.
Jensen RT
Ann Oncol 1999;10 Suppl 4:170-6. PMID: 10436815
Repeat hepatectomy for cancer.
Elias D, Lasser P, Hoang JM, Leclere J, Debaene B, Bognel C, Spencer A, Rougier P
Br J Surg 1993 Dec;80(12):1557-62. doi: 10.1002/bjs.1800801223. PMID: 8298926
Bronchial carcinoids. Review of 124 cases.
McCaughan BC, Martini N, Bains MS
J Thorac Cardiovasc Surg 1985 Jan;89(1):8-17. PMID: 2981373
APUD cells and the apudomas. A concept relevant to anaesthesia and endocrinology.
Whitwam JG
Anaesthesia 1977 Oct;32(9):879-88. doi: 10.1111/j.1365-2044.1977.tb10110.x. PMID: 23705

Diagnosis

Subcorneal pustular dermatosis: 50 years on.
Cheng S, Edmonds E, Ben-Gashir M, Yu RC
Clin Exp Dermatol 2008 May;33(3):229-33. Epub 2008 Mar 18 doi: 10.1111/j.1365-2230.2008.02706.x. PMID: 18355359
The role of somatostatin and its analogs in the diagnosis and treatment of tumors.
Lamberts SW, Krenning EP, Reubi JC
Endocr Rev 1991 Nov;12(4):450-82. doi: 10.1210/edrv-12-4-450. PMID: 1684746
Dermatologic manifestations of internal cancer.
Thiers BH
CA Cancer J Clin 1986 May-Jun;36(3):130-48. doi: 10.3322/canjclin.36.3.130. PMID: 3011224
Tumors of the endocrine pancreas.
Friesen SR
N Engl J Med 1982 Mar 11;306(10):580-90. doi: 10.1056/NEJM198203113061005. PMID: 6120456
Ectopic hormones--biochemical aspects.
Ratcliffe JG
Scott Med J 1980 Apr;25(2):146-50. doi: 10.1177/003693308002500215. PMID: 6256853

Therapy

Subcorneal pustular dermatosis: 50 years on.
Cheng S, Edmonds E, Ben-Gashir M, Yu RC
Clin Exp Dermatol 2008 May;33(3):229-33. Epub 2008 Mar 18 doi: 10.1111/j.1365-2230.2008.02706.x. PMID: 18355359
Pancreatic endocrine tumours, immunotherapy and gene therapy: chemotherapy and interferon therapy of endocrine tumours.
Veenhof CH
Ann Oncol 1999;10 Suppl 4:185-7. PMID: 10436818
Somatostatin analogue treatment of neuroendocrine tumours.
de Herder WW, van der Lely AJ, Lamberts SW
Postgrad Med J 1996 Jul;72(849):403-8. doi: 10.1136/pgmj.72.849.403. PMID: 8935599Free PMC Article
Transcatheter treatment of hepatic metastases.
Pentecost MJ
AJR Am J Roentgenol 1993 Jun;160(6):1171-5. doi: 10.2214/ajr.160.6.8388617. PMID: 8388617
Multidirectional differentiation in neuroendocrine neoplasms.
DeLellis RA, Tischler AS, Wolfe HJ
J Histochem Cytochem 1984 Aug;32(8):899-904. doi: 10.1177/32.8.6146648. PMID: 6146648

Prognosis

Neuroendocrine tumours--analysis of own material--a nine--year retrospective study.
Kaliszewski K, Bednarz W, Łukieńczuk T, Balcerzak W, Kaliszewska M, Dawiskiba J
Hepatogastroenterology 2010 Mar-Apr;57(98):236-41. PMID: 20583420
Pancreatic endocrine tumors: recent advances.
Jensen RT
Ann Oncol 1999;10 Suppl 4:170-6. PMID: 10436815
Repeat hepatectomy for cancer.
Elias D, Lasser P, Hoang JM, Leclere J, Debaene B, Bognel C, Spencer A, Rougier P
Br J Surg 1993 Dec;80(12):1557-62. doi: 10.1002/bjs.1800801223. PMID: 8298926
Neuroendocrine tumors. A European view.
Buchanan KD, Johnston CF, O'Hare MM, Ardill JE, Shaw C, Collins JS, Watson RG, Atkinson AB, Hadden DR, Kennedy TL
Am J Med 1986 Dec 22;81(6B):14-22. doi: 10.1016/0002-9343(86)90581-4. PMID: 2879446
Bronchial carcinoids. Review of 124 cases.
McCaughan BC, Martini N, Bains MS
J Thorac Cardiovasc Surg 1985 Jan;89(1):8-17. PMID: 2981373

Clinical prediction guides

Neuroendocrine tumours--analysis of own material--a nine--year retrospective study.
Kaliszewski K, Bednarz W, Łukieńczuk T, Balcerzak W, Kaliszewska M, Dawiskiba J
Hepatogastroenterology 2010 Mar-Apr;57(98):236-41. PMID: 20583420
Diagnostic yield and reliability of endoscopic ultrasonography in patients with idiopathic acute pancreatitis.
Vila JJ, Vicuña M, Irisarri R, de la Higuera BG, Ruiz-Clavijo D, Rodríguez-Gutiérrez C, Urman JM, Bolado F, Jiménez FJ, Arín A
Scand J Gastroenterol 2010 Mar;45(3):375-81. doi: 10.3109/00365520903508894. PMID: 20034361
Adjuvant local irradiation for Merkel cell carcinoma.
Lewis KG, Weinstock MA, Weaver AL, Otley CC
Arch Dermatol 2006 Jun;142(6):693-700. doi: 10.1001/archderm.142.6.693. PMID: 16785371
Bronchial carcinoids. Review of 124 cases.
McCaughan BC, Martini N, Bains MS
J Thorac Cardiovasc Surg 1985 Jan;89(1):8-17. PMID: 2981373
Multidirectional differentiation in neuroendocrine neoplasms.
DeLellis RA, Tischler AS, Wolfe HJ
J Histochem Cytochem 1984 Aug;32(8):899-904. doi: 10.1177/32.8.6146648. PMID: 6146648

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