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Abnormal tubulointerstitial morphology

MedGen UID:
892966
Concept ID:
C4025732
Anatomical Abnormality
Synonym: Tubulointerstitial abnormalities
 
HPO: HP:0001969

Definition

An abnormality that involves the tubules and interstitial tissue of the kidney. [from HPO]

Conditions with this feature

Nephropathy, progressive tubulointerstitial, with cholestatic liver disease
MedGen UID:
355562
Concept ID:
C1865831
Disease or Syndrome

Professional guidelines

PubMed

Standardization of Uveitis Nomenclature (SUN) Working Group
Am J Ophthalmol 2021 Aug;228:255-261. Epub 2021 May 11 doi: 10.1016/j.ajo.2021.03.041. PMID: 33845023Free PMC Article
Kawano M, Saeki T, Nakashima H, Nishi S, Yamaguchi Y, Hisano S, Yamanaka N, Inoue D, Yamamoto M, Takahashi H, Nomura H, Taguchi T, Umehara H, Makino H, Saito T
Clin Exp Nephrol 2011 Oct;15(5):615-626. Epub 2011 Sep 7 doi: 10.1007/s10157-011-0521-2. PMID: 21898030
Lüscher TF, Wanner C, Hauri D, Siegenthaler W, Vetter W
Cardiology 1985;72 Suppl 1:33-45. doi: 10.1159/000173942. PMID: 3902229

Recent clinical studies

Etiology

Yang X, Liu Y, Zhu X, Chen P, Xie X, Xu T, Zhang X, Zhao Y
Ren Fail 2023 Dec;45(1):2228920. doi: 10.1080/0886022X.2023.2228920. PMID: 37369635Free PMC Article
Petzold F, Billot K, Chen X, Henry C, Filhol E, Martin Y, Avramescu M, Douillet M, Morinière V, Krug P, Jeanpierre C, Tory K, Boyer O, Burgun A, Servais A, Salomon R, Benmerah A, Heidet L, Garcelon N, Antignac C, Zaidan M, Saunier S; INSERM–Necker Hospital NPH collaborative group
Kidney Int 2023 Aug;104(2):378-387. Epub 2023 May 23 doi: 10.1016/j.kint.2023.05.007. PMID: 37230223
Lemoine H, Raud L, Foulquier F, Sayer JA, Lambert B, Olinger E, Lefèvre S, Knebelmann B, Harris PC, Trouvé P, Desprès A, Duneau G, Matignon M, Poyet A, Jourde-Chiche N, Guerrot D, Lemoine S, Seret G, Barroso-Gil M, Bingham C, Gilbert R; Genomics England Research Consortium; Genkyst Study Group, Le Meur Y, Audrézet MP, Cornec-Le Gall E
Am J Hum Genet 2022 Aug 4;109(8):1484-1499. Epub 2022 Jul 26 doi: 10.1016/j.ajhg.2022.06.013. PMID: 35896117Free PMC Article
Ponticelli C, Moroni G, Glassock RJ
Clin J Am Soc Nephrol 2014 Aug 7;9(8):1479-87. Epub 2014 Apr 3 doi: 10.2215/CJN.12571213. PMID: 24700797Free PMC Article
Fioretto P, Mauer M
Semin Nephrol 2007 Mar;27(2):195-207. doi: 10.1016/j.semnephrol.2007.01.012. PMID: 17418688Free PMC Article

Diagnosis

Petzold F, Billot K, Chen X, Henry C, Filhol E, Martin Y, Avramescu M, Douillet M, Morinière V, Krug P, Jeanpierre C, Tory K, Boyer O, Burgun A, Servais A, Salomon R, Benmerah A, Heidet L, Garcelon N, Antignac C, Zaidan M, Saunier S; INSERM–Necker Hospital NPH collaborative group
Kidney Int 2023 Aug;104(2):378-387. Epub 2023 May 23 doi: 10.1016/j.kint.2023.05.007. PMID: 37230223
Armstrong ME, Thomas CP
Curr Opin Nephrol Hypertens 2019 Mar;28(2):183-194. doi: 10.1097/MNH.0000000000000486. PMID: 30601180
Kamath N, Iyengar A
Pediatr Nephrol 2018 Aug;33(8):1317-1326. Epub 2017 Sep 6 doi: 10.1007/s00467-017-3785-2. PMID: 28879600
Saeki T, Kawano M
Kidney Int 2014 Feb;85(2):251-7. Epub 2013 Oct 9 doi: 10.1038/ki.2013.393. PMID: 24107849
Vehaskari VM
Adv Chronic Kidney Dis 2011 Sep;18(5):317-23. doi: 10.1053/j.ackd.2011.07.001. PMID: 21896372

Therapy

Jia G, Lastra G, Bostick BP, LahamKaram N, Laakkonen JP, Ylä-Herttuala S, Whaley-Connell A
Am J Physiol Renal Physiol 2024 Sep 1;327(3):F519-F531. Epub 2024 Jul 18 doi: 10.1152/ajprenal.00135.2024. PMID: 39024357Free PMC Article
Wang B, Yang LN, Yang LT, Liang Y, Guo F, Fu P, Ma L
Acta Pharmacol Sin 2024 Jan;45(1):150-165. Epub 2023 Sep 11 doi: 10.1038/s41401-023-01156-w. PMID: 37696989Free PMC Article
Yang X, Liu Y, Zhu X, Chen P, Xie X, Xu T, Zhang X, Zhao Y
Ren Fail 2023 Dec;45(1):2228920. doi: 10.1080/0886022X.2023.2228920. PMID: 37369635Free PMC Article
Kamath N, Iyengar A
Pediatr Nephrol 2018 Aug;33(8):1317-1326. Epub 2017 Sep 6 doi: 10.1007/s00467-017-3785-2. PMID: 28879600
Saeki T, Kawano M
Kidney Int 2014 Feb;85(2):251-7. Epub 2013 Oct 9 doi: 10.1038/ki.2013.393. PMID: 24107849

Prognosis

Mori Y, Ajay AK, Chang JH, Mou S, Zhao H, Kishi S, Li J, Brooks CR, Xiao S, Woo HM, Sabbisetti VS, Palmer SC, Galichon P, Li L, Henderson JM, Kuchroo VK, Hawkins J, Ichimura T, Bonventre JV
Cell Metab 2021 May 4;33(5):1042-1061.e7. doi: 10.1016/j.cmet.2021.04.004. PMID: 33951465Free PMC Article
Trionfini P, Benigni A, Remuzzi G
Nat Rev Nephrol 2015 Jan;11(1):23-33. Epub 2014 Nov 11 doi: 10.1038/nrneph.2014.202. PMID: 25385286
Saeki T, Kawano M
Kidney Int 2014 Feb;85(2):251-7. Epub 2013 Oct 9 doi: 10.1038/ki.2013.393. PMID: 24107849
Vehaskari VM
Adv Chronic Kidney Dis 2011 Sep;18(5):317-23. doi: 10.1053/j.ackd.2011.07.001. PMID: 21896372
Remuzzi G, Zoja C, Bertani T
Curr Opin Nephrol Hypertens 1993 May;2(3):465-74. doi: 10.1097/00041552-199305000-00015. PMID: 7922207

Clinical prediction guides

Mori Y, Ajay AK, Chang JH, Mou S, Zhao H, Kishi S, Li J, Brooks CR, Xiao S, Woo HM, Sabbisetti VS, Palmer SC, Galichon P, Li L, Henderson JM, Kuchroo VK, Hawkins J, Ichimura T, Bonventre JV
Cell Metab 2021 May 4;33(5):1042-1061.e7. doi: 10.1016/j.cmet.2021.04.004. PMID: 33951465Free PMC Article
Kuroda N, Nao T, Fukuhara H, Karashima T, Inoue K, Taniguchi Y, Takeuchi M, Zen Y, Sato Y, Notohara K, Yoshino T
Int J Clin Exp Pathol 2014;7(9):6379-85. Epub 2014 Aug 15 PMID: 25337295Free PMC Article
Saeki T, Kawano M
Kidney Int 2014 Feb;85(2):251-7. Epub 2013 Oct 9 doi: 10.1038/ki.2013.393. PMID: 24107849
Salomon R, Saunier S, Niaudet P
Pediatr Nephrol 2009 Dec;24(12):2333-44. Epub 2008 Jul 8 doi: 10.1007/s00467-008-0840-z. PMID: 18607645Free PMC Article
Remuzzi G, Zoja C, Bertani T
Curr Opin Nephrol Hypertens 1993 May;2(3):465-74. doi: 10.1097/00041552-199305000-00015. PMID: 7922207

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