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Tubulointerstitial bacterial infiltration

MedGen UID:
1708915
•Concept ID:
C5397584
•
Finding
Synonym: Renal tubulointerstitial bacterial organisms
 
HPO: HP:0020204

Definition

Tubulointerstitial infiltration of bacteria identified on routine and/or special (Brown-Hopps) stains. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTubulointerstitial bacterial infiltration

Recent clinical studies

Etiology

Kidney biopsy findings in vancomycin-induced acute kidney injury: a pooled analysis.
Bellos I, Pergialiotis V, Perrea DN
Int Urol Nephrol 2022 Jan;54(1):137-148. Epub 2021 Mar 14 doi: 10.1007/s11255-021-02831-9. PMID: 33715061

Diagnosis

Kidney biopsy findings in vancomycin-induced acute kidney injury: a pooled analysis.
Bellos I, Pergialiotis V, Perrea DN
Int Urol Nephrol 2022 Jan;54(1):137-148. Epub 2021 Mar 14 doi: 10.1007/s11255-021-02831-9. PMID: 33715061
Diffuse infiltrative lymphocytosis syndrome presenting as reversible acute kidney injury associated with Gram-negative bacterial infection in patients with newly diagnosed HIV infection.
Yoo J, Baumstein D, Kuppachi S, Singh A, Chander PN
Am J Kidney Dis 2011 May;57(5):752-5. Epub 2011 Feb 4 doi: 10.1053/j.ajkd.2010.12.010. PMID: 21295898
Pathological evidence of rhabdomyolysis-induced acute tubulointerstitial nephritis accompanying Legionella pneumophila pneumonia.
Shimura C, Saraya T, Wada H, Takata S, Mikura S, Yasutake T, Kato J, Kato A, Yamamoto M, Watanabe M, Yokoyama T, Kurai D, Ishii H, Aoshima M, Yamada A, Goto H
J Clin Pathol 2008 Sep;61(9):1062-3. Epub 2008 Jun 13 doi: 10.1136/jcp.2008.057000. PMID: 18552170
Acute renal failure in a 3-year-old child as part of the drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome following hepatitis A.
Garnier A, El Marabet el H, Kwon T, Peuchmaur M, Mourier O, Baudouin V, Deschênes G, Loirat C
Pediatr Nephrol 2008 Apr;23(4):667-9. Epub 2007 Nov 27 doi: 10.1007/s00467-007-0676-y. PMID: 18040726
Biopsy-proved acute tubulointerstitial nephritis and toxic epidermal necrolysis associated with vancomycin.
Hsu SI
Pharmacotherapy 2001 Oct;21(10):1233-9. doi: 10.1592/phco.21.15.1233.33901. PMID: 11601669

Therapy

Kidney biopsy findings in vancomycin-induced acute kidney injury: a pooled analysis.
Bellos I, Pergialiotis V, Perrea DN
Int Urol Nephrol 2022 Jan;54(1):137-148. Epub 2021 Mar 14 doi: 10.1007/s11255-021-02831-9. PMID: 33715061
Sustained Tubulointerstitial Inflammation in Kidney with Severe Leptospirosis.
Tanaka K, Tanabe K, Nishii N, Takiue K, Sugiyama H, Wada J
Intern Med 2017;56(10):1179-1184. Epub 2017 May 15 doi: 10.2169/internalmedicine.56.8084. PMID: 28502933Free PMC Article
Pathological evidence of rhabdomyolysis-induced acute tubulointerstitial nephritis accompanying Legionella pneumophila pneumonia.
Shimura C, Saraya T, Wada H, Takata S, Mikura S, Yasutake T, Kato J, Kato A, Yamamoto M, Watanabe M, Yokoyama T, Kurai D, Ishii H, Aoshima M, Yamada A, Goto H
J Clin Pathol 2008 Sep;61(9):1062-3. Epub 2008 Jun 13 doi: 10.1136/jcp.2008.057000. PMID: 18552170
Acute renal failure in a 3-year-old child as part of the drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome following hepatitis A.
Garnier A, El Marabet el H, Kwon T, Peuchmaur M, Mourier O, Baudouin V, Deschênes G, Loirat C
Pediatr Nephrol 2008 Apr;23(4):667-9. Epub 2007 Nov 27 doi: 10.1007/s00467-007-0676-y. PMID: 18040726
Biopsy-proved acute tubulointerstitial nephritis and toxic epidermal necrolysis associated with vancomycin.
Hsu SI
Pharmacotherapy 2001 Oct;21(10):1233-9. doi: 10.1592/phco.21.15.1233.33901. PMID: 11601669

Prognosis

Kidney biopsy findings in vancomycin-induced acute kidney injury: a pooled analysis.
Bellos I, Pergialiotis V, Perrea DN
Int Urol Nephrol 2022 Jan;54(1):137-148. Epub 2021 Mar 14 doi: 10.1007/s11255-021-02831-9. PMID: 33715061
Kidney dendritic cells induce innate immunity against bacterial pyelonephritis.
Tittel AP, Heuser C, Ohliger C, Knolle PA, Engel DR, Kurts C
J Am Soc Nephrol 2011 Aug;22(8):1435-41. Epub 2011 Jul 14 doi: 10.1681/ASN.2010101072. PMID: 21757770Free PMC Article

Clinical prediction guides

Cytokine and Chemokine Expression in Kidneys during Chronic Leptospirosis in Reservoir and Susceptible Animal Models.
Matsui M, Roche L, Geroult S, Soupé-Gilbert ME, Monchy D, Huerre M, Goarant C
PLoS One 2016;11(5):e0156084. Epub 2016 May 24 doi: 10.1371/journal.pone.0156084. PMID: 27219334Free PMC Article
Diffuse infiltrative lymphocytosis syndrome presenting as reversible acute kidney injury associated with Gram-negative bacterial infection in patients with newly diagnosed HIV infection.
Yoo J, Baumstein D, Kuppachi S, Singh A, Chander PN
Am J Kidney Dis 2011 May;57(5):752-5. Epub 2011 Feb 4 doi: 10.1053/j.ajkd.2010.12.010. PMID: 21295898
Acute human pyelonephritis: leukocytic infiltration of tubules and localization of bacteria.
Iványi B, Rumpelt HJ, Thoenes W
Virchows Arch A Pathol Anat Histopathol 1988;414(1):29-37. doi: 10.1007/BF00749735. PMID: 3144801

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