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Reduced ratio of renal calcium clearance to creatinine clearance

MedGen UID:
871134
•Concept ID:
C4025605
•
Finding
Synonyms: Reduced ration of kidney calcium clearance to creatinine clearance; Reduced ration of renal Ca clearance to creatinine clearance; Reduced ration of renal Ca2+ to creatinine clearance
 
HPO: HP:0003513

Definition

A reduction of the ratio of renal calcium clearance to creatinine clearance to below 0.01. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVReduced ratio of renal calcium clearance to creatinine clearance

Professional guidelines

PubMed

Adaptor protein-2 sigma subunit mutations causing familial hypocalciuric hypercalcaemia type 3 (FHH3) demonstrate genotype-phenotype correlations, codon bias and dominant-negative effects.
Hannan FM, Howles SA, Rogers A, Cranston T, Gorvin CM, Babinsky VN, Reed AA, Thakker CE, Bockenhauer D, Brown RS, Connell JM, Cook J, Darzy K, Ehtisham S, Graham U, Hulse T, Hunter SJ, Izatt L, Kumar D, McKenna MJ, McKnight JA, Morrison PJ, Mughal MZ, O'Halloran D, Pearce SH, Porteous ME, Rahman M, Richardson T, Robinson R, Scheers I, Siddique H, Van't Hoff WG, Wang T, Whyte MP, Nesbit MA, Thakker RV
Hum Mol Genet 2015 Sep 15;24(18):5079-92. Epub 2015 Jun 16 doi: 10.1093/hmg/ddv226. PMID: 26082470Free PMC Article

Recent clinical studies

Therapy

Incidence and clinical characteristics of hypertriglyceridemic acute pancreatitis: A retrospective single-center study.
Lin XY, Zeng Y, Zhang ZC, Lin ZH, Chen LC, Ye ZS
World J Gastroenterol 2022 Aug 7;28(29):3946-3959. doi: 10.3748/wjg.v28.i29.3946. PMID: 36157550Free PMC Article
A mathematical estimation for quantified calcium supplementation during intermittent hemodialysis using regional citrate anticoagulation.
Bi X, Zhang Q, Zhuang F, Ding F
Artif Organs 2022 Jun;46(6):1122-1131. Epub 2022 Jan 11 doi: 10.1111/aor.14164. PMID: 34978734
Population pharmacokinetics of rosuvastatin: implications of renal impairment, race, and dyslipidaemia.
Tzeng TB, Schneck DW, Birmingham BK, Mitchell PD, Zhang H, Martin PD, Kung LP
Curr Med Res Opin 2008 Sep;24(9):2575-85. Epub 2008 Jul 31 doi: 10.1185/03007990802312807. PMID: 18674408
(L)-2-oxothiazolidine-4-carboxylate in the treatment of primary hyperoxaluria type 1.
Holmes RP, Assimos DG, Wilson DM, Milliner DS
BJU Int 2001 Dec;88(9):858-62. doi: 10.1046/j.1464-4096.2001.02439.x. PMID: 11851603
The influence of orthophosphate on the renal handling of inorganic pyrophosphate in man and dog.
Russell RG, Bisaz S, Fleisch H
Clin Sci Mol Med 1976 Nov;51(5):435-43. doi: 10.1042/cs0510435. PMID: 186225

Prognosis

Incidence and clinical characteristics of hypertriglyceridemic acute pancreatitis: A retrospective single-center study.
Lin XY, Zeng Y, Zhang ZC, Lin ZH, Chen LC, Ye ZS
World J Gastroenterol 2022 Aug 7;28(29):3946-3959. doi: 10.3748/wjg.v28.i29.3946. PMID: 36157550Free PMC Article
Population pharmacokinetics of rosuvastatin: implications of renal impairment, race, and dyslipidaemia.
Tzeng TB, Schneck DW, Birmingham BK, Mitchell PD, Zhang H, Martin PD, Kung LP
Curr Med Res Opin 2008 Sep;24(9):2575-85. Epub 2008 Jul 31 doi: 10.1185/03007990802312807. PMID: 18674408
Parathyroid hormone and large related C-terminal fragments increase at different rates with worsening of renal function in chronic kidney disease patients. A possible indicator of bone turnover status?
Donadio C, Ardini M, Lucchesi A, Donadio E, Cantor T
Clin Nephrol 2007 Mar;67(3):131-9. doi: 10.5414/cnp67131. PMID: 17390737
Alteration of heart rate variability parameters in nondiabetic hemodialysis patients.
Tong YQ, Hou HM
Am J Nephrol 2007;27(1):63-9. Epub 2007 Jan 24 doi: 10.1159/000099013. PMID: 17259695
Accelerated coronary artery calcification in mildly reduced renal function of high-risk hypertensives: a 3-year prospective observation.
Bursztyn M, Motro M, Grossman E, Shemesh J
J Hypertens 2003 Oct;21(10):1953-9. doi: 10.1097/00004872-200310000-00024. PMID: 14508203

Clinical prediction guides

Incidence and clinical characteristics of hypertriglyceridemic acute pancreatitis: A retrospective single-center study.
Lin XY, Zeng Y, Zhang ZC, Lin ZH, Chen LC, Ye ZS
World J Gastroenterol 2022 Aug 7;28(29):3946-3959. doi: 10.3748/wjg.v28.i29.3946. PMID: 36157550Free PMC Article
Population pharmacokinetics of rosuvastatin: implications of renal impairment, race, and dyslipidaemia.
Tzeng TB, Schneck DW, Birmingham BK, Mitchell PD, Zhang H, Martin PD, Kung LP
Curr Med Res Opin 2008 Sep;24(9):2575-85. Epub 2008 Jul 31 doi: 10.1185/03007990802312807. PMID: 18674408
Effect of an energy-restricted, high-protein, low-fat diet relative to a conventional high-carbohydrate, low-fat diet on weight loss, body composition, nutritional status, and markers of cardiovascular health in obese women.
Noakes M, Keogh JB, Foster PR, Clifton PM
Am J Clin Nutr 2005 Jun;81(6):1298-306. doi: 10.1093/ajcn/81.6.1298. PMID: 15941879
Accelerated coronary artery calcification in mildly reduced renal function of high-risk hypertensives: a 3-year prospective observation.
Bursztyn M, Motro M, Grossman E, Shemesh J
J Hypertens 2003 Oct;21(10):1953-9. doi: 10.1097/00004872-200310000-00024. PMID: 14508203
Renal tubular function in children and adolescents with Gitelman's syndrome, the hypocalciuric variant of Bartter's syndrome.
Peters N, Bettinelli A, Spicher I, Basilico E, Metta MG, Bianchetti MG
Nephrol Dial Transplant 1995;10(8):1313-9. PMID: 8538920

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