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Abnormality of urine calcium concentration

MedGen UID:: 869017
•Concept ID:: C4023434
•: Finding

Synonyms:	Abnormality of urine Ca concentration; Abnormality of urine Ca2+ concentration

HPO:	HP:0011280

Definition

An abnormality of calcium concentration in the urine. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAbnormality of urine calcium concentration

Congenital Systemic Disorder
- Abnormality of the genitourinary system
  - Abnormality of the urinary system
    - Abnormality of the urinary system physiology
      - Abnormality of urine homeostasis
        Abnormal urinary electrolyte concentration
        Abnormality of urine calcium concentration
        Hypercalciuria
        Hypocalciuria
        Reduced ratio of renal calcium clearance to creatinine clearance
        Renal calcium wasting

Conditions with this feature

Primary hyperoxaluria, type II

MedGen UID:: 120616
•Concept ID:: C0268165
•: Disease or Syndrome

Primary hyperoxaluria type 2 (PH2), caused by deficiency of the enzyme glyoxylate reductase/hydroxypyruvate reductase (GR/HPR), is characterized by recurrent nephrolithiasis (deposition of calcium oxalate in the renal pelvis/urinary tract), nephrocalcinosis (deposition of calcium oxalate in the renal parenchyma), and end-stage renal disease (ESRD). After ESRD, oxalosis (widespread tissue deposition of calcium oxalate) usually develops. Symptom onset is typically in childhood.

See: Condition Record

Primary hyperoxaluria, type II

Professional guidelines

PubMed

Pathophysiology-based treatment of idiopathic calcium kidney stones.

Coe FL, Evan A, Worcester E
Clin J Am Soc Nephrol 2011 Aug;6(8):2083-92. doi: 10.2215/CJN.11321210. PMID: 21825103 Free PMC Article

Renal stone disease: Causes, evaluation and medical treatment.

Heilberg IP, Schor N
Arq Bras Endocrinol Metabol 2006 Aug;50(4):823-31. doi: 10.1590/s0004-27302006000400027. PMID: 17117307

Lopinavir/ritonavir: a review of its use in the management of HIV infection.

Cvetkovic RS, Goa KL
Drugs 2003;63(8):769-802. doi: 10.2165/00003495-200363080-00004. PMID: 12662125

See all (14)

Recent clinical studies

Therapy

Incomplete Distal Renal Tubular Acidosis and Kidney Stones.

Fuster DG, Moe OW
Adv Chronic Kidney Dis 2018 Jul;25(4):366-374. doi: 10.1053/j.ackd.2018.05.007. PMID: 30139463 Free PMC Article

Pathophysiology-based treatment of idiopathic calcium kidney stones.

Coe FL, Evan A, Worcester E
Clin J Am Soc Nephrol 2011 Aug;6(8):2083-92. doi: 10.2215/CJN.11321210. PMID: 21825103 Free PMC Article

Diet-induced metabolic acidosis.

Adeva MM, Souto G
Clin Nutr 2011 Aug;30(4):416-21. Epub 2011 Apr 9 doi: 10.1016/j.clnu.2011.03.008. PMID: 21481501

Determinants and mechanisms of enamel fluorosis.

Whitford GM
Ciba Found Symp 1997;205:226-41; discussion 241-5. doi: 10.1002/9780470515303.ch16. PMID: 9189628

Vitamin D metabolite-mediated hypercalcemia.

Adams JS
Endocrinol Metab Clin North Am 1989 Sep;18(3):765-78. PMID: 2673772

See all (109)

Prognosis

Early predictors of abnormal MRI patterns in asphyxiated infants: S100B protein urine levels.

Bersani I, Gasparroni G, Bashir M, Aboulgar H, Mufeed H, Iskander I, Kornacka M, Gruzfeld D, Dotta A, Campi F, Longo D, Savarese I, Braguglia A, Tina LG, Nigro F, Serpero L, Strozzi MC, Maconi A, Ianniello P, Di Battista C, D'Adamo E, Gavilanes D, Gazzolo D
Clin Chem Lab Med 2022 Oct 26;60(11):1745-1752. Epub 2022 Aug 18 doi: 10.1515/cclm-2022-0559. PMID: 35977430

Urinary minerals excretion among primary schoolchildren in Dubai-United Arab Emirates.

Al Ghali R, El-Mallah C, Obeid O, El-Saleh O, Smail L, Haroun D
PLoS One 2021;16(8):e0255195. Epub 2021 Aug 5 doi: 10.1371/journal.pone.0255195. PMID: 34351961 Free PMC Article

Rhabdomyolysis.

Zimmerman JL, Shen MC
Chest 2013 Sep;144(3):1058-1065. doi: 10.1378/chest.12-2016. PMID: 24008958

Pathophysiology-based treatment of idiopathic calcium kidney stones.

Coe FL, Evan A, Worcester E
Clin J Am Soc Nephrol 2011 Aug;6(8):2083-92. doi: 10.2215/CJN.11321210. PMID: 21825103 Free PMC Article

Diet-induced metabolic acidosis.

Adeva MM, Souto G
Clin Nutr 2011 Aug;30(4):416-21. Epub 2011 Apr 9 doi: 10.1016/j.clnu.2011.03.008. PMID: 21481501

See all (41)

Clinical prediction guides

Urinary minerals excretion among primary schoolchildren in Dubai-United Arab Emirates.

Al Ghali R, El-Mallah C, Obeid O, El-Saleh O, Smail L, Haroun D
PLoS One 2021;16(8):e0255195. Epub 2021 Aug 5 doi: 10.1371/journal.pone.0255195. PMID: 34351961 Free PMC Article

Rhabdomyolysis.

Zimmerman JL, Shen MC
Chest 2013 Sep;144(3):1058-1065. doi: 10.1378/chest.12-2016. PMID: 24008958

Pathophysiology-based treatment of idiopathic calcium kidney stones.

Coe FL, Evan A, Worcester E
Clin J Am Soc Nephrol 2011 Aug;6(8):2083-92. doi: 10.2215/CJN.11321210. PMID: 21825103 Free PMC Article

Clinical and metabolic evaluation of Korean patients with urolithiasis.

Park KJ, Jeon SS, Han DH, Lee SY
Scand J Clin Lab Invest 2011 Oct;71(6):481-5. Epub 2011 Jun 30 doi: 10.3109/00365513.2011.587528. PMID: 21714706

Diet-induced metabolic acidosis.

Adeva MM, Souto G
Clin Nutr 2011 Aug;30(4):416-21. Epub 2011 Apr 9 doi: 10.1016/j.clnu.2011.03.008. PMID: 21481501

See all (84)