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Hyperoxemia

MedGen UID:
868512
•Concept ID:
C4022910
•
Pathologic Function
HPO: HP:0012419

Definition

An abnormally high level of blood oxygen. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHyperoxemia

Professional guidelines

PubMed

German S3 Guideline: Oxygen Therapy in the Acute Care of Adult Patients.
Gottlieb J, Capetian P, Hamsen U, Janssens U, Karagiannidis C, Kluge S, Nothacker M, Roiter S, Volk T, Worth H, Fühner T
Respiration 2022;101(2):214-252. Epub 2021 Dec 21 doi: 10.1159/000520294. PMID: 34933311
Perceptions of Hyperoxemia and Conservative Oxygen Therapy in the Management of Acute Respiratory Failure.
Curtis BR, Rak KJ, Richardson A, Linstrum K, Kahn JM, Girard TD
Ann Am Thorac Soc 2021 Aug;18(8):1369-1379. doi: 10.1513/AnnalsATS.202007-802OC. PMID: 33332994Free PMC Article
Retinopathy of prematurity - from recognition of risk factors to treatment recommendations.
Fagerholm R, Vesti E
Duodecim 2017;133(4):337-44. PMID: 29205980

Recent clinical studies

Etiology

The outcomes of using high oxygen concentration in pediatric patients.
Saracoglu A, Zengin SU, Ozturk N, Niftaliyev S, Harman F, Aykac Z
J Clin Monit Comput 2022 Oct;36(5):1341-1346. Epub 2021 Oct 27 doi: 10.1007/s10877-021-00765-2. PMID: 34705168
Perioperative Lung Protection: Clinical Implications.
Hol L, Nijbroek SGLH, Schultz MJ
Anesth Analg 2020 Dec;131(6):1721-1729. doi: 10.1213/ANE.0000000000005187. PMID: 33186160
Oxygen Therapy and Pulmonary Hypertension in Preterm Infants.
Gentle SJ, Abman SH, Ambalavanan N
Clin Perinatol 2019 Sep;46(3):611-619. Epub 2019 Jun 20 doi: 10.1016/j.clp.2019.05.009. PMID: 31345551
Oxygen in the critically ill: friend or foe?
Damiani E, Donati A, Girardis M
Curr Opin Anaesthesiol 2018 Apr;31(2):129-135. doi: 10.1097/ACO.0000000000000559. PMID: 29334496
Hyperoxia and infection.
Hopf HW, Holm J
Best Pract Res Clin Anaesthesiol 2008 Sep;22(3):553-69. doi: 10.1016/j.bpa.2008.06.001. PMID: 18831303

Diagnosis

Monitoring SpO(2): The Basics of Retinopathy of Prematurity (Back to Basics) and Targeting Oxygen Saturation.
Sola A, Leslie Altimier, Teresa Montes Bueno M, Muñoz CE
Crit Care Nurs Clin North Am 2024 Mar;36(1):69-98. Epub 2023 Sep 15 doi: 10.1016/j.cnc.2023.08.004. PMID: 38296377
Hyperoxemia in postsurgical sepsis/septic shock patients is associated with reduced mortality.
Martín-Fernández M, Heredia-Rodríguez M, González-Jiménez I, Lorenzo-López M, Gómez-Pesquera E, Poves-Álvarez R, Álvarez FJ, Jorge-Monjas P, Beltrán-DeHeredia J, Gutiérrez-Abejón E, Herrera-Gómez F, Guzzo G, Gómez-Sánchez E, Tamayo-Velasco Á, Aller R, Pelosi P, Villar J, Tamayo E
Crit Care 2022 Jan 10;26(1):4. doi: 10.1186/s13054-021-03875-0. PMID: 35000603Free PMC Article
German S3 Guideline: Oxygen Therapy in the Acute Care of Adult Patients.
Gottlieb J, Capetian P, Hamsen U, Janssens U, Karagiannidis C, Kluge S, Nothacker M, Roiter S, Volk T, Worth H, Fühner T
Respiration 2022;101(2):214-252. Epub 2021 Dec 21 doi: 10.1159/000520294. PMID: 34933311
Retinopathy of prematurity - from recognition of risk factors to treatment recommendations.
Fagerholm R, Vesti E
Duodecim 2017;133(4):337-44. PMID: 29205980
Hyperoxia and infection.
Hopf HW, Holm J
Best Pract Res Clin Anaesthesiol 2008 Sep;22(3):553-69. doi: 10.1016/j.bpa.2008.06.001. PMID: 18831303

Therapy

Hyperoxia-induced lung injury in acute respiratory distress syndrome: what is its relative impact?
Lilien TA, van Meenen DMP, Schultz MJ, Bos LDJ, Bem RA
Am J Physiol Lung Cell Mol Physiol 2023 Jul 1;325(1):L9-L16. Epub 2023 May 2 doi: 10.1152/ajplung.00443.2022. PMID: 37129255
Respiratory Instability and Hypoxemia Episodes in Preterm Infants.
Bancalari E, Claure N
Am J Perinatol 2018 May;35(6):534-536. Epub 2018 Apr 25 doi: 10.1055/s-0038-1637760. PMID: 29694990
Oxygen in the critically ill: friend or foe?
Damiani E, Donati A, Girardis M
Curr Opin Anaesthesiol 2018 Apr;31(2):129-135. doi: 10.1097/ACO.0000000000000559. PMID: 29334496
How much oxygen in adult cardiac arrest?
Dell'Anna AM, Lamanna I, Vincent JL, Taccone FS
Crit Care 2014 Oct 7;18(5):555. doi: 10.1186/s13054-014-0555-4. PMID: 25636001Free PMC Article
Hyperoxia and infection.
Hopf HW, Holm J
Best Pract Res Clin Anaesthesiol 2008 Sep;22(3):553-69. doi: 10.1016/j.bpa.2008.06.001. PMID: 18831303

Prognosis

Arterial hyperoxia and mortality in the cardiac intensive care unit.
Jentzer JC, van Diepen S, Alviar C, Miller PE, Metkus TS, Geller BJ, Kashani KB
Curr Probl Cardiol 2024 Oct;49(10):102738. Epub 2024 Jul 17 doi: 10.1016/j.cpcardiol.2024.102738. PMID: 39025170
What are standard monitoring devices for anesthesia in future?
Obara S, Hirata N, Hagihira S, Yoshida K, Kotake Y, Takagi S, Masui K
J Anesth 2024 Aug;38(4):537-541. Epub 2024 May 15 doi: 10.1007/s00540-024-03347-z. PMID: 38748064
Blood gas analyses in hyperbaric and underwater environments: a systematic review.
Paganini M, Moon RE, Boccalon N, Melloni GEM, Giacon TA, Camporesi EM, Bosco G
J Appl Physiol (1985) 2022 Feb 1;132(2):283-293. Epub 2021 Dec 23 doi: 10.1152/japplphysiol.00569.2021. PMID: 34941439
Perioperative Lung Protection: Clinical Implications.
Hol L, Nijbroek SGLH, Schultz MJ
Anesth Analg 2020 Dec;131(6):1721-1729. doi: 10.1213/ANE.0000000000005187. PMID: 33186160
How much oxygen in adult cardiac arrest?
Dell'Anna AM, Lamanna I, Vincent JL, Taccone FS
Crit Care 2014 Oct 7;18(5):555. doi: 10.1186/s13054-014-0555-4. PMID: 25636001Free PMC Article

Clinical prediction guides

What are standard monitoring devices for anesthesia in future?
Obara S, Hirata N, Hagihira S, Yoshida K, Kotake Y, Takagi S, Masui K
J Anesth 2024 Aug;38(4):537-541. Epub 2024 May 15 doi: 10.1007/s00540-024-03347-z. PMID: 38748064
The outcomes of using high oxygen concentration in pediatric patients.
Saracoglu A, Zengin SU, Ozturk N, Niftaliyev S, Harman F, Aykac Z
J Clin Monit Comput 2022 Oct;36(5):1341-1346. Epub 2021 Oct 27 doi: 10.1007/s10877-021-00765-2. PMID: 34705168
Perioperative Lung Protection: Clinical Implications.
Hol L, Nijbroek SGLH, Schultz MJ
Anesth Analg 2020 Dec;131(6):1721-1729. doi: 10.1213/ANE.0000000000005187. PMID: 33186160
Oxygen in the critically ill: friend or foe?
Damiani E, Donati A, Girardis M
Curr Opin Anaesthesiol 2018 Apr;31(2):129-135. doi: 10.1097/ACO.0000000000000559. PMID: 29334496
Hyperoxia and infection.
Hopf HW, Holm J
Best Pract Res Clin Anaesthesiol 2008 Sep;22(3):553-69. doi: 10.1016/j.bpa.2008.06.001. PMID: 18831303

Recent systematic reviews

Exposure to severe hyperoxemia worsens survival and neurological outcome in patients supported by veno-arterial extracorporeal membrane oxygenation: A meta-analysis.
Tigano S, Caruso A, Liotta C, LaVia L, Vargas M, Romagnoli S, Landoni G, Sanfilippo F
Resuscitation 2024 Jan;194:110071. Epub 2023 Dec 5 doi: 10.1016/j.resuscitation.2023.110071. PMID: 38061577
The effects of exposure to severe hyperoxemia on neurological outcome and mortality after cardiac arrest.
LA Via L, Astuto M, Bignami EG, Busalacchi D, Dezio V, Girardis M, Lanzafame B, Ristagno G, Pelosi P, Sanfilippo F
Minerva Anestesiol 2022 Oct;88(10):853-863. Epub 2022 Mar 23 doi: 10.23736/S0375-9393.22.16449-7. PMID: 35319851
Effects of hyperoxemia on aneurysmal subarachnoid hemorrhage outcomes: a systematic review and meta-analysis.
Ahn J, Mastorakos P, Sokolowski JD, Chen CJ, Kellogg R, Park MS
Neurosurg Focus 2022 Mar;52(3):E7. doi: 10.3171/2021.12.FOCUS21660. PMID: 35231897
The Effect of Hyperoxemia on Neurological Outcomes of Adult Patients: A Systematic Review and Meta-Analysis.
Hirunpattarasilp C, Shiina H, Na-Ek N, Attwell D
Neurocrit Care 2022 Jun;36(3):1027-1043. Epub 2022 Jan 31 doi: 10.1007/s12028-021-01423-w. PMID: 35099713Free PMC Article
A Systematic Review of the Effects of Hyperoxia in Acutely Ill Patients: Should We Aim for Less?
Stolmeijer R, Bouma HR, Zijlstra JG, Drost-de Klerck AM, Ter Maaten JC, Ligtenberg JJM
Biomed Res Int 2018;2018:7841295. Epub 2018 May 14 doi: 10.1155/2018/7841295. PMID: 29888278Free PMC Article

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