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Abnormal blood oxygen level

MedGen UID:
663395
•Concept ID:
C0580517
•
Finding
Synonyms: Abnormal blood O2 level; Abnormal blood oxygen levels; Abnormal O2 blood concentration; Blood oxygen level abnormal; Blood oxygen level outside reference range
SNOMED CT: Blood oxygen level abnormal (167026000); Blood oxygen level outside reference range (167026000)
 
HPO: HP:0500165

Definition

An abnormality of the partial pressure of oxygen in the arterial blood. [from HPO]

Professional guidelines

PubMed

Eisenmenger syndrome: diagnosis, prognosis and clinical management.
Arvanitaki A, Giannakoulas G, Baumgartner H, Lammers AE
Heart 2020 Nov;106(21):1638-1645. Epub 2020 Jul 20 doi: 10.1136/heartjnl-2020-316665. PMID: 32690623
Clinical Practice Guideline: Tonsillectomy in Children (Update)-Executive Summary.
Mitchell RB, Archer SM, Ishman SL, Rosenfeld RM, Coles S, Finestone SA, Friedman NR, Giordano T, Hildrew DM, Kim TW, Lloyd RM, Parikh SR, Shulman ST, Walner DL, Walsh SA, Nnacheta LC
Otolaryngol Head Neck Surg 2019 Feb;160(2):187-205. doi: 10.1177/0194599818807917. PMID: 30921525
Clinical Practice Guideline: Tonsillectomy in Children (Update).
Mitchell RB, Archer SM, Ishman SL, Rosenfeld RM, Coles S, Finestone SA, Friedman NR, Giordano T, Hildrew DM, Kim TW, Lloyd RM, Parikh SR, Shulman ST, Walner DL, Walsh SA, Nnacheta LC
Otolaryngol Head Neck Surg 2019 Feb;160(1_suppl):S1-S42. doi: 10.1177/0194599818801757. PMID: 30798778

Recent clinical studies

Etiology

Regional Glymphatic Abnormality in Behavioral Variant Frontotemporal Dementia.
Jiang D, Liu L, Kong Y, Chen Z, Rosa-Neto P, Chen K, Ren L, Chu M, Wu L; Frontotemporal Lobar Degeneration Neuroimaging Initiative
Ann Neurol 2023 Sep;94(3):442-456. Epub 2023 Jun 14 doi: 10.1002/ana.26710. PMID: 37243334Free PMC Article
Coblation supraglottoplasty: a ten-year experience in a tertiary referral hospital.
El-Sobki A, Ibrahim RAE, Amer A, Hashish MI, El-Deeb ME, El-Kholy NA, Abdelmeguid AS
Eur Arch Otorhinolaryngol 2022 Feb;279(2):865-874. Epub 2021 Oct 16 doi: 10.1007/s00405-021-07130-8. PMID: 34654950
Delivery room oxygen physiology and respiratory interventions for newborns with cyanotic congenital heart disease.
Thomas AR, Ma AL, Weinberg DD, Huber M, Ades A, Rychik J, Foglia EE
J Perinatol 2021 Sep;41(9):2309-2316. Epub 2021 Mar 23 doi: 10.1038/s41372-021-01029-2. PMID: 33758390
Oxygen Saturation and Perfusion Index-Based Enhanced Critical Congenital Heart Disease Screening.
Siefkes H, Kair L, Tancredi DJ, Vasquez B, Garcia L, Bedford-Mu C, Lakshminrusimha S
Am J Perinatol 2020 Jan;37(2):158-165. Epub 2019 Apr 19 doi: 10.1055/s-0039-1685445. PMID: 31003242
Postoperative management: the role of mixed venous oxygen saturation monitoring.
Bradley SM, Atz AM
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2005:22-7. doi: 10.1053/j.pcsu.2005.01.002. PMID: 15818354

Diagnosis

Eisenmenger syndrome: diagnosis, prognosis and clinical management.
Arvanitaki A, Giannakoulas G, Baumgartner H, Lammers AE
Heart 2020 Nov;106(21):1638-1645. Epub 2020 Jul 20 doi: 10.1136/heartjnl-2020-316665. PMID: 32690623
MR imaging of the fetal heart.
Marini D, van Amerom J, Saini BS, Sun L, Seed M
J Magn Reson Imaging 2020 Apr;51(4):1030-1044. Epub 2019 Jun 13 doi: 10.1002/jmri.26815. PMID: 31190452
Transposition of the great arteries: When echocardiography does not match the clinical picture.
Dhillon GS, Fernandes CJ, Khan A, Heinle JS, Lopez KN
J Clin Ultrasound 2018 Nov;46(9):617-622. Epub 2018 Aug 30 doi: 10.1002/jcu.22615. PMID: 30160304Free PMC Article
Platypnoea-orthodeoxia syndrome exacerbated by kyphosis progression.
Iwai T, Miyamoto T, Miyazaki R, Nozato T
BMJ Case Rep 2018 Jul 30;2018 doi: 10.1136/bcr-2017-223514. PMID: 30061123Free PMC Article
Scimitar syndrome.
Ielasi A, Latib A, Agricola E, Montorfano M, Colombo A
J Cardiovasc Med (Hagerstown) 2011 Mar;12(3):176-7. doi: 10.2459/JCM.0b013e328332f3e2. PMID: 20093947

Therapy

Iron deficiency in patients with a Fontan circulation and its impact on exercise capacity.
van Hassel G, Rivrud SCS, Timmerman FJ, van der Meer P, Hoendermis ES, Liem ET, Berger RMF, van Melle JP
Open Heart 2024 Jun 5;11(1) doi: 10.1136/openhrt-2024-002693. PMID: 38839367Free PMC Article
In Silico Evaluation of a Self-powered Venous Ejector Pump for Fontan Patients.
Rasooli R, Giljarhus KET, Hiorth A, Jolma IW, Vinningland JL, de Lange C, Brun H, Holmstrom H
Cardiovasc Eng Technol 2023 Jun;14(3):428-446. Epub 2023 Mar 6 doi: 10.1007/s13239-023-00663-5. PMID: 36877450Free PMC Article
Blalock-Taussig Shunt versus Ductal Stent in the Palliation of Duct Dependent Pulmonary Circulation; A Systematic Review and Metanalysis.
Fakhry AbdelMassih A, Menshawey R, Menshawey E, El-Maghraby AE, Sabry AO, Kamel A, Seyam MY, Elshawarbi P, Ahmed SN, Salem SS, Ragab S, Nada Y, Agha H
Curr Probl Cardiol 2022 Sep;47(9):100885. Epub 2021 May 8 doi: 10.1016/j.cpcardiol.2021.100885. PMID: 34175152
Biventricular Conversion in Unseptatable Hearts: "Ventricular Switch".
Najm HK, Karamlou T, Ahmad M, Hassan S, Yaman M, Stewart R, Pettersson G
Semin Thorac Cardiovasc Surg 2021 Spring;33(1):172-180. Epub 2020 Aug 26 doi: 10.1053/j.semtcvs.2020.08.010. PMID: 32858218
Supraglottoplasty in Infants: A Staged Approach.
Walner DL, Neumann DB, Hamming KK, Miller RP
Ann Otol Rhinol Laryngol 2015 Oct;124(10):803-7. Epub 2015 May 5 doi: 10.1177/0003489415585869. PMID: 25944597

Prognosis

Impact of the superior cavopulmonary anastomosis on cerebral oxygenation.
Thatte N, Zhou L, Kheir JN
Cardiol Young 2020 Apr;30(4):585-587. Epub 2020 Mar 16 doi: 10.1017/S1047951120000517. PMID: 32172701
Investigating the oxygenation of brain arteriovenous malformations using quantitative susceptibility mapping.
Biondetti E, Rojas-Villabona A, Sokolska M, Pizzini FB, Jäger HR, Thomas DL, Shmueli K
Neuroimage 2019 Oct 1;199:440-453. Epub 2019 May 7 doi: 10.1016/j.neuroimage.2019.05.014. PMID: 31075392
Transposition of the great arteries: When echocardiography does not match the clinical picture.
Dhillon GS, Fernandes CJ, Khan A, Heinle JS, Lopez KN
J Clin Ultrasound 2018 Nov;46(9):617-622. Epub 2018 Aug 30 doi: 10.1002/jcu.22615. PMID: 30160304Free PMC Article
Effects of persistent Fontan fenestration patency on cardiopulmonary exercise testing variables.
Heal ME, Jackson LB, Atz AM, Butts RJ
Congenit Heart Dis 2017 Jul;12(4):399-402. Epub 2017 Jun 15 doi: 10.1111/chd.12451. PMID: 28618202Free PMC Article
Aprotinin improves outcome of single-ventricle palliation.
Tweddell JS, Berger S, Frommelt PC, Pelech AN, Lewis DA, Fedderly RT, Frommelt MA, McManus TS, Mussatto KA, Kessel MW, Litwin SB
Ann Thorac Surg 1996 Nov;62(5):1329-35; discussion 1335-6. doi: 10.1016/0003-4975(96)00670-4. PMID: 8893564

Clinical prediction guides

Assessment of functional capacity among students with univentricular heart.
Ampuero C, Silva R, Valderrama P, Covarrubias E, Astudillo P, Zelada P, Clavería C
Arch Argent Pediatr 2020 Oct;118(5):343-349. doi: 10.5546/aap.2020.eng.343. PMID: 32924398
Eisenmenger syndrome: diagnosis, prognosis and clinical management.
Arvanitaki A, Giannakoulas G, Baumgartner H, Lammers AE
Heart 2020 Nov;106(21):1638-1645. Epub 2020 Jul 20 doi: 10.1136/heartjnl-2020-316665. PMID: 32690623
Transposition of the great arteries: When echocardiography does not match the clinical picture.
Dhillon GS, Fernandes CJ, Khan A, Heinle JS, Lopez KN
J Clin Ultrasound 2018 Nov;46(9):617-622. Epub 2018 Aug 30 doi: 10.1002/jcu.22615. PMID: 30160304Free PMC Article
Scimitar syndrome.
Ielasi A, Latib A, Agricola E, Montorfano M, Colombo A
J Cardiovasc Med (Hagerstown) 2011 Mar;12(3):176-7. doi: 10.2459/JCM.0b013e328332f3e2. PMID: 20093947
Clinical use of blade atrial septostomy.
Park SC, Neches WH, Zuberbuhler JR, Lenox CC, Mathews RA, Fricker FJ, Zoltun RA
Circulation 1978 Oct;58(4):600-6. doi: 10.1161/01.cir.58.4.600. PMID: 688569

Recent systematic reviews

Intraoperative Regional Cerebral Oxygenation During Pediatric Thoracoscopic Surgery: A Systematic Review.
Prasad G, Singh A, Kainth D, Khanna P, Anand S
J Laparoendosc Adv Surg Tech A 2024 Mar;34(3):274-279. Epub 2023 Oct 20 doi: 10.1089/lap.2023.0228. PMID: 37862569
Blalock-Taussig Shunt versus Ductal Stent in the Palliation of Duct Dependent Pulmonary Circulation; A Systematic Review and Metanalysis.
Fakhry AbdelMassih A, Menshawey R, Menshawey E, El-Maghraby AE, Sabry AO, Kamel A, Seyam MY, Elshawarbi P, Ahmed SN, Salem SS, Ragab S, Nada Y, Agha H
Curr Probl Cardiol 2022 Sep;47(9):100885. Epub 2021 May 8 doi: 10.1016/j.cpcardiol.2021.100885. PMID: 34175152
Pulse oximetry screening for critical congenital heart defects.
Plana MN, Zamora J, Suresh G, Fernandez-Pineda L, Thangaratinam S, Ewer AK
Cochrane Database Syst Rev 2018 Mar 1;3(3):CD011912. doi: 10.1002/14651858.CD011912.pub2. PMID: 29494750Free PMC Article
Does This Child Have Pneumonia?: The Rational Clinical Examination Systematic Review.
Shah SN, Bachur RG, Simel DL, Neuman MI
JAMA 2017 Aug 1;318(5):462-471. doi: 10.1001/jama.2017.9039. PMID: 28763554
Near-infrared spectroscopy: what we know and what we need to know--a systematic review of the congenital heart disease literature.
Hirsch JC, Charpie JR, Ohye RG, Gurney JG
J Thorac Cardiovasc Surg 2009 Jan;137(1):154-9, 159e1-12. Epub 2008 Sep 24 doi: 10.1016/j.jtcvs.2008.08.005. PMID: 19154918

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