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Abnormal earlobe morphology

MedGen UID:
867434
•Concept ID:
C4021808
•
Anatomical Abnormality
Synonym: Abnormality of earlobe
 
HPO: HP:0000363

Definition

An abnormality of the lobule of pinna. [from HPO]

Conditions with this feature

Syndactyly-polydactyly-ear lobe syndrome
MedGen UID:
348333
•Concept ID:
C1861347
•
Disease or Syndrome
A rare, genetic, congenital limb malformation syndrome characterized by complete cutaneous syndactyly between toes 1-2, ulnar polydactyly (ranging from nubbins to an almost complete additional finger) and earlobe malformations. Additionally, abnormalities along the medial border of the foot are observed on X-ray imaging. There have been no further descriptions in the literature since 1976.
See: Condition Record
Syndactyly-polydactyly-ear lobe syndrome

Professional guidelines

PubMed

Novel phenotypes and genotypes in Antley-Bixler syndrome caused by cytochrome P450 oxidoreductase deficiency: based on the first cohort of Chinese children.
Fan L, Ren X, Song Y, Su C, Fu J, Gong C
Orphanet J Rare Dis 2019 Dec 30;14(1):299. doi: 10.1186/s13023-019-1283-2. PMID: 31888681Free PMC Article
Clinical features and management issues in Mowat-Wilson syndrome.
Adam MP, Schelley S, Gallagher R, Brady AN, Barr K, Blumberg B, Shieh JT, Graham J, Slavotinek A, Martin M, Keppler-Noreuil K, Storm AL, Hudgins L
Am J Med Genet A 2006 Dec 15;140(24):2730-41. doi: 10.1002/ajmg.a.31530. PMID: 17103451

Recent clinical studies

Etiology

Auricular spoon-shaped crus malformation including variants: Clinical features and a novel surgical approach.
Park C
J Plast Reconstr Aesthet Surg 2024 Sep;96:256-262. Epub 2024 Jul 17 doi: 10.1016/j.bjps.2024.07.029. PMID: 39116803
A Different Approach for Protruding Earlobe Correction-Modified Fish-tail Technique.
Sert B, Oral MA, Turan O, Uyar I
Aesthetic Plast Surg 2024 Jun;48(11):2011-2017. Epub 2024 Mar 4 doi: 10.1007/s00266-024-03912-7. PMID: 38438764Free PMC Article
Relationship between the earlobe crease and brain white matter abnormalities in apparently healthy subjects.
Ata Korkmaz HA
Turk J Med Sci 2019 Apr 18;49(2):604-609. doi: 10.3906/sag-1812-124. PMID: 30889943Free PMC Article
Otoplasty with an unusual cartilage scoring approach.
Gümüş N, Yılmaz S
J Plast Surg Hand Surg 2016;50(1):19-24. Epub 2015 Jul 15 doi: 10.3109/2000656X.2015.1065265. PMID: 26176319
Cleft earlobe repair.
Fearon J, Cuadros CL
Ann Plast Surg 1990 Mar;24(3):252-7. doi: 10.1097/00000637-199003000-00010. PMID: 2316987

Diagnosis

Horn-shaped Symmetric Nodules on the Earlobes: An Unusual Presentation of First Branchial Cleft Anomaly.
Kwon HJ, Yang YB, Oh DY
J Craniofac Surg 2022 Sep 1;33(6):e592-e594. Epub 2022 Jul 29 doi: 10.1097/SCS.0000000000008678. PMID: 36054896
In-Depth Look at the Anatomical Relationship of the Lesser Occipital Nerve, Great Auricular Nerve, and Spinal Accessory Nerve and Their Implication in Safety of Operations in the Posterior Triangle of the Neck.
Amirlak B, Lu KB, Erickson CR, Sanniec K, Totonchi A, Peled ZM, Cheng JC
Plast Reconstr Surg 2020 Sep;146(3):509-514. doi: 10.1097/PRS.0000000000007049. PMID: 32453270
Sheldon-Hall syndrome.
Toydemir RM, Bamshad MJ
Orphanet J Rare Dis 2009 Mar 23;4:11. doi: 10.1186/1750-1172-4-11. PMID: 19309503Free PMC Article
Protracted superficial Wegener's granulomatosis.
Sinovich V, Snow J
Australas J Dermatol 2003 Aug;44(3):207-14. doi: 10.1046/j.1440-0960.2003.00689.x. PMID: 12869048
Topics in pediatric plastic surgery.
Denk MJ
Pediatr Clin North Am 1998 Dec;45(6):1479-506, ix. doi: 10.1016/s0031-3955(05)70100-0. PMID: 9889763

Therapy

How to Avoid Earlobe Deformation in Face Lift.
Marlen S, Constantin S, Georgii S
Aesthetic Plast Surg 2015 Aug;39(4):483-90. Epub 2015 Jun 6 doi: 10.1007/s00266-015-0467-y. PMID: 26047921
Prevention of earlobe deformity in face-lifting.
Coscia J, Huang A, Stevenson TR
Ann Plast Surg 2013 Apr;70(4):389-91. doi: 10.1097/SAP.0b013e31828a0cbd. PMID: 23486143
Earlobe rejuvenation.
Hotta T
Plast Surg Nurs 2011 Jan-Mar;31(1):39-40. doi: 10.1097/PSN.0b013e31820f53fc. PMID: 21368648
Protracted superficial Wegener's granulomatosis.
Sinovich V, Snow J
Australas J Dermatol 2003 Aug;44(3):207-14. doi: 10.1046/j.1440-0960.2003.00689.x. PMID: 12869048
Plastic and reconstructive surgery of the earlobe.
Clevens RA, Baker SR
Facial Plast Surg 1995 Oct;11(4):301-9. doi: 10.1055/s-2008-1064546. PMID: 9046618

Prognosis

Relationship between the earlobe crease and brain white matter abnormalities in apparently healthy subjects.
Ata Korkmaz HA
Turk J Med Sci 2019 Apr 18;49(2):604-609. doi: 10.3906/sag-1812-124. PMID: 30889943Free PMC Article
The association of circulating inflammatory and oxidative stress biomarker levels with diagonal earlobe crease in patients with atherosclerotic diseases.
Koyama T, Watanabe H, Ito H
J Cardiol 2016 Apr;67(4):347-51. Epub 2015 Jul 7 doi: 10.1016/j.jjcc.2015.06.002. PMID: 26162942
HEAR MAPS a classification for congenital microtia/atresia based on the evaluation of 742 patients.
Roberson JB Jr, Goldsztein H, Balaker A, Schendel SA, Reinisch JF
Int J Pediatr Otorhinolaryngol 2013 Sep;77(9):1551-4. Epub 2013 Aug 7 doi: 10.1016/j.ijporl.2013.07.002. PMID: 23931903
Bilateral diagonal earlobe crease and coronary artery disease: a significant association.
Evrengül H, Dursunoğlu D, Kaftan A, Zoghi M, Tanriverdi H, Zungur M, Kiliç M
Dermatology 2004;209(4):271-5. doi: 10.1159/000080847. PMID: 15539887
Diagonal earlobe creases and prognosis in patients with suspected coronary artery disease.
Elliott WJ, Powell LH
Am J Med 1996 Feb;100(2):205-11. doi: 10.1016/s0002-9343(97)89460-0. PMID: 8629656

Clinical prediction guides

Prograde transposition for anteriorly low-set earlobe in lobule-type microtia reconstruction.
Deng Y, Yang Y, Wang T, Wang B, Wang P, Zhi J, Xu D, Jiang H
J Plast Reconstr Aesthet Surg 2024 May;92:145-150. Epub 2024 Mar 5 doi: 10.1016/j.bjps.2024.02.073. PMID: 38518626
A Different Approach for Protruding Earlobe Correction-Modified Fish-tail Technique.
Sert B, Oral MA, Turan O, Uyar I
Aesthetic Plast Surg 2024 Jun;48(11):2011-2017. Epub 2024 Mar 4 doi: 10.1007/s00266-024-03912-7. PMID: 38438764Free PMC Article
Horn-shaped Symmetric Nodules on the Earlobes: An Unusual Presentation of First Branchial Cleft Anomaly.
Kwon HJ, Yang YB, Oh DY
J Craniofac Surg 2022 Sep 1;33(6):e592-e594. Epub 2022 Jul 29 doi: 10.1097/SCS.0000000000008678. PMID: 36054896
Relationship between the earlobe crease and brain white matter abnormalities in apparently healthy subjects.
Ata Korkmaz HA
Turk J Med Sci 2019 Apr 18;49(2):604-609. doi: 10.3906/sag-1812-124. PMID: 30889943Free PMC Article
Bilateral diagonal earlobe crease and coronary artery disease: a significant association.
Evrengül H, Dursunoğlu D, Kaftan A, Zoghi M, Tanriverdi H, Zungur M, Kiliç M
Dermatology 2004;209(4):271-5. doi: 10.1159/000080847. PMID: 15539887

Recent systematic reviews

Earlobe Correction of the Pierced Ear: A Systematic Review of the Literature and Principles for Surgical Reconstruction.
Grohmann M, Weiland T, Tuca AC, Wimbauer JM
Facial Plast Surg Aesthet Med 2023 Mar-Apr;25(2):83-89. Epub 2022 Feb 9 doi: 10.1089/fpsam.2021.0269. PMID: 35138923

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