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Oversedated

MedGen UID:
852661
•Concept ID:
C0542127
•
Finding
Synonym: Oversedation

Definition

A level of sedation that is greater than the intended level. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOversedated

Professional guidelines

PubMed

Reported lifetime aberrant drug-taking behaviors are predictive of current substance use and mental health problems in primary care patients.
Fleming MF, Davis J, Passik SD
Pain Med 2008 Nov;9(8):1098-106. Epub 2008 Aug 18 doi: 10.1111/j.1526-4637.2008.00491.x. PMID: 18721174Free PMC Article

Recent clinical studies

Etiology

Evaluation of Nonintubated Analgesia Practices in Critical Care Transport.
Esteves AM, Gilchrist HE, Markwood JM, Bondurant M, Roginski MA
Air Med J 2023 Jul-Aug;42(4):259-262. Epub 2023 Apr 14 doi: 10.1016/j.amj.2023.03.006. PMID: 37356886
Identification of acute brain failure using electronic medical records.
Reddy DR, Singh TD, Guru PK, Sakusic A, Gajic O, O'Horo JC, Rabinstein AA
J Crit Care 2016 Aug;34:12-6. Epub 2016 Mar 16 doi: 10.1016/j.jcrc.2016.03.008. PMID: 27288602Free PMC Article
Effects of single-dose gabapentin on postoperative pain and morphine consumption after cardiac surgery.
Menda F, Köner O, Sayın M, Ergenoğlu M, Küçükaksu S, Aykaç B
J Cardiothorac Vasc Anesth 2010 Oct;24(5):808-13. Epub 2010 Jan 6 doi: 10.1053/j.jvca.2009.10.023. PMID: 20056448
The COMFORT behavioural scale and the modified FLACC scale in paediatric intensive care.
Johansson M, Kokinsky E
Nurs Crit Care 2009 May-Jun;14(3):122-30. doi: 10.1111/j.1478-5153.2009.00323.x. PMID: 19366409
Remifentanil versus remifentanil/midazolam for ambulatory surgery during monitored anesthesia care.
Gold MI, Watkins WD, Sung YF, Yarmush J, Chung F, Uy NT, Maurer W, Clarke MY, Jamerson BD
Anesthesiology 1997 Jul;87(1):51-7. doi: 10.1097/00000542-199707000-00007. PMID: 9232133

Diagnosis

Early processed electroencephalography for the monitoring of deeply sedated mechanically ventilated critically ill patients.
Favre E, Bernini A, Miroz JP, Abed-Maillard S, Ramelet AS, Oddo M
Nurs Crit Care 2024 Nov;29(6):1781-1787. Epub 2023 Nov 23 doi: 10.1111/nicc.13009. PMID: 37997530
Identification of acute brain failure using electronic medical records.
Reddy DR, Singh TD, Guru PK, Sakusic A, Gajic O, O'Horo JC, Rabinstein AA
J Crit Care 2016 Aug;34:12-6. Epub 2016 Mar 16 doi: 10.1016/j.jcrc.2016.03.008. PMID: 27288602Free PMC Article
Methadone conversion in infants and children: Retrospective cohort study of 199 pediatric inpatients.
Fife A, Postier A, Flood A, Friedrichsdorf SJ
J Opioid Manag 2016 May-Jun;12(2):123-30. doi: 10.5055/jom.2016.0324. PMID: 27194197
Comparison of two ketamine-propofol dosing regimens for sedation during interventional radiology procedures.
Erden IA, Pamuk AG, Akinci SB, Koseoglu A, Aypar U
Minerva Anestesiol 2010 Apr;76(4):260-5. Epub 2009 Nov 24 PMID: 20332739
The COMFORT behavioural scale and the modified FLACC scale in paediatric intensive care.
Johansson M, Kokinsky E
Nurs Crit Care 2009 May-Jun;14(3):122-30. doi: 10.1111/j.1478-5153.2009.00323.x. PMID: 19366409

Therapy

Evaluation of Nonintubated Analgesia Practices in Critical Care Transport.
Esteves AM, Gilchrist HE, Markwood JM, Bondurant M, Roginski MA
Air Med J 2023 Jul-Aug;42(4):259-262. Epub 2023 Apr 14 doi: 10.1016/j.amj.2023.03.006. PMID: 37356886
Personalized sedation goal for agitated delirium in patients with cancer: Balancing comfort and communication.
Hui D, De La Rosa A, Urbauer DL, Nguyen T, Bruera E
Cancer 2021 Dec 15;127(24):4694-4701. Epub 2021 Aug 25 doi: 10.1002/cncr.33876. PMID: 34432293Free PMC Article
The Effectiveness of α2 Agonists As Sedatives in Pediatric Critical Care: A Propensity Score-Matched Cohort Study.
Hayden JC, Doherty DR, Dawkins I, Leacy FP, Healy M, Breatnach CV, Cousins G, Gallagher PJ
Crit Care Med 2019 Jul;47(7):e580-e586. doi: 10.1097/CCM.0000000000003789. PMID: 31033500
The COMFORT behavioural scale and the modified FLACC scale in paediatric intensive care.
Johansson M, Kokinsky E
Nurs Crit Care 2009 May-Jun;14(3):122-30. doi: 10.1111/j.1478-5153.2009.00323.x. PMID: 19366409
Remifentanil versus remifentanil/midazolam for ambulatory surgery during monitored anesthesia care.
Gold MI, Watkins WD, Sung YF, Yarmush J, Chung F, Uy NT, Maurer W, Clarke MY, Jamerson BD
Anesthesiology 1997 Jul;87(1):51-7. doi: 10.1097/00000542-199707000-00007. PMID: 9232133

Prognosis

Personalized sedation goal for agitated delirium in patients with cancer: Balancing comfort and communication.
Hui D, De La Rosa A, Urbauer DL, Nguyen T, Bruera E
Cancer 2021 Dec 15;127(24):4694-4701. Epub 2021 Aug 25 doi: 10.1002/cncr.33876. PMID: 34432293Free PMC Article
Reported lifetime aberrant drug-taking behaviors are predictive of current substance use and mental health problems in primary care patients.
Fleming MF, Davis J, Passik SD
Pain Med 2008 Nov;9(8):1098-106. Epub 2008 Aug 18 doi: 10.1111/j.1526-4637.2008.00491.x. PMID: 18721174Free PMC Article
Epidemiology of sedation and sedation adequacy for mechanically ventilated patients in a medical and surgical intensive care unit.
Weinert CR, Calvin AD
Crit Care Med 2007 Feb;35(2):393-401. doi: 10.1097/01.CCM.0000254339.18639.1D. PMID: 17205015

Clinical prediction guides

Personalized sedation goal for agitated delirium in patients with cancer: Balancing comfort and communication.
Hui D, De La Rosa A, Urbauer DL, Nguyen T, Bruera E
Cancer 2021 Dec 15;127(24):4694-4701. Epub 2021 Aug 25 doi: 10.1002/cncr.33876. PMID: 34432293Free PMC Article
Identification of acute brain failure using electronic medical records.
Reddy DR, Singh TD, Guru PK, Sakusic A, Gajic O, O'Horo JC, Rabinstein AA
J Crit Care 2016 Aug;34:12-6. Epub 2016 Mar 16 doi: 10.1016/j.jcrc.2016.03.008. PMID: 27288602Free PMC Article
Effects of single-dose gabapentin on postoperative pain and morphine consumption after cardiac surgery.
Menda F, Köner O, Sayın M, Ergenoğlu M, Küçükaksu S, Aykaç B
J Cardiothorac Vasc Anesth 2010 Oct;24(5):808-13. Epub 2010 Jan 6 doi: 10.1053/j.jvca.2009.10.023. PMID: 20056448
The COMFORT behavioural scale and the modified FLACC scale in paediatric intensive care.
Johansson M, Kokinsky E
Nurs Crit Care 2009 May-Jun;14(3):122-30. doi: 10.1111/j.1478-5153.2009.00323.x. PMID: 19366409
Epidemiology of sedation and sedation adequacy for mechanically ventilated patients in a medical and surgical intensive care unit.
Weinert CR, Calvin AD
Crit Care Med 2007 Feb;35(2):393-401. doi: 10.1097/01.CCM.0000254339.18639.1D. PMID: 17205015

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