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Central Nervous System Signs and Symptoms

MedGen UID:
416166
Concept ID:
C2828177
Sign or Symptom

Definition

Signs and symptoms associated with disturbances within the central nervous system, which includes the brain, spinal cord and meninges. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCentral Nervous System Signs and Symptoms

Professional guidelines

PubMed

McGinley MP, Goldschmidt CH, Rae-Grant AD
JAMA 2021 Feb 23;325(8):765-779. doi: 10.1001/jama.2020.26858. PMID: 33620411
Bhattacharyya N, Gubbels SP, Schwartz SR, Edlow JA, El-Kashlan H, Fife T, Holmberg JM, Mahoney K, Hollingsworth DB, Roberts R, Seidman MD, Steiner RW, Do BT, Voelker CC, Waguespack RW, Corrigan MD
Otolaryngol Head Neck Surg 2017 Mar;156(3_suppl):S1-S47. doi: 10.1177/0194599816689667. PMID: 28248609
Klit H, Finnerup NB, Jensen TS
Lancet Neurol 2009 Sep;8(9):857-68. doi: 10.1016/S1474-4422(09)70176-0. PMID: 19679277

Recent clinical studies

Etiology

van Griensven H, Schmid A, Trendafilova T, Low M
J Orthop Sports Phys Ther 2020 Nov;50(11):592-596. doi: 10.2519/jospt.2020.0610. PMID: 33131390
Borghammer P, Van Den Berge N
J Parkinsons Dis 2019;9(s2):S281-S295. doi: 10.3233/JPD-191721. PMID: 31498132Free PMC Article
Sommer C, Leinders M, Üçeyler N
Pain 2018 Mar;159(3):595-602. doi: 10.1097/j.pain.0000000000001122. PMID: 29447138
Monteleone P, Mascagni G, Giannini A, Genazzani AR, Simoncini T
Nat Rev Endocrinol 2018 Apr;14(4):199-215. Epub 2018 Feb 2 doi: 10.1038/nrendo.2017.180. PMID: 29393299
Sanzarello I, Merlini L, Rosa MA, Perrone M, Frugiuele J, Borghi R, Faldini C
J Back Musculoskelet Rehabil 2016 Nov 21;29(4):625-633. doi: 10.3233/BMR-160685. PMID: 27062464

Diagnosis

Younger DS
Handb Clin Neurol 2023;196:231-250. doi: 10.1016/B978-0-323-98817-9.00018-1. PMID: 37620071
Tinnirello A, Mazzoleni S, Santi C
Biomolecules 2021 Aug 23;11(8) doi: 10.3390/biom11081256. PMID: 34439922Free PMC Article
McGinley MP, Goldschmidt CH, Rae-Grant AD
JAMA 2021 Feb 23;325(8):765-779. doi: 10.1001/jama.2020.26858. PMID: 33620411
van Griensven H, Schmid A, Trendafilova T, Low M
J Orthop Sports Phys Ther 2020 Nov;50(11):592-596. doi: 10.2519/jospt.2020.0610. PMID: 33131390
Meacham K, Shepherd A, Mohapatra DP, Haroutounian S
Curr Pain Headache Rep 2017 Jun;21(6):28. doi: 10.1007/s11916-017-0629-5. PMID: 28432601

Therapy

McGinley MP, Goldschmidt CH, Rae-Grant AD
JAMA 2021 Feb 23;325(8):765-779. doi: 10.1001/jama.2020.26858. PMID: 33620411
Donnelly CR, Andriessen AS, Chen G, Wang K, Jiang C, Maixner W, Ji RR
Neurotherapeutics 2020 Jul;17(3):846-860. doi: 10.1007/s13311-020-00905-7. PMID: 32820378Free PMC Article
Tang D, Li H, Chen L
Adv Exp Med Biol 2019;1130:109-128. doi: 10.1007/978-981-13-6123-4_7. PMID: 30915704
Sluka KA, Frey-Law L, Hoeger Bement M
Pain 2018 Sep;159 Suppl 1(Suppl 1):S91-S97. doi: 10.1097/j.pain.0000000000001235. PMID: 30113953Free PMC Article
Ji RR, Nackley A, Huh Y, Terrando N, Maixner W
Anesthesiology 2018 Aug;129(2):343-366. doi: 10.1097/ALN.0000000000002130. PMID: 29462012Free PMC Article

Prognosis

McGinley MP, Goldschmidt CH, Rae-Grant AD
JAMA 2021 Feb 23;325(8):765-779. doi: 10.1001/jama.2020.26858. PMID: 33620411
Fregoso G, Wang A, Tseng K, Wang J
Pain Physician 2019 Sep;22(5):479-488. PMID: 31561647
Seroussi R, Singh V, Fry A
Phys Med Rehabil Clin N Am 2015 May;26(2):359-73. Epub 2015 Mar 7 doi: 10.1016/j.pmr.2015.01.003. PMID: 25952070
Patterson JL, Carapetian SA, Hageman JR, Kelley KR
Pediatr Ann 2013 Dec;42(12):249-54. doi: 10.3928/00904481-20131122-09. PMID: 24295158
Helbok R, Broessner G, Pfausler B, Schmutzhard E
J Neurol 2009 Feb;256(2):168-75. Epub 2009 Feb 17 doi: 10.1007/s00415-009-0122-0. PMID: 19224317

Clinical prediction guides

McGinley MP, Goldschmidt CH, Rae-Grant AD
JAMA 2021 Feb 23;325(8):765-779. doi: 10.1001/jama.2020.26858. PMID: 33620411
Huebra L, Coelho FM, Filho FMR, Barsottini OG, Pedroso JL
Curr Neurol Neurosci Rep 2019 Jul 25;19(8):59. doi: 10.1007/s11910-019-0968-1. PMID: 31342187
Monteleone P, Mascagni G, Giannini A, Genazzani AR, Simoncini T
Nat Rev Endocrinol 2018 Apr;14(4):199-215. Epub 2018 Feb 2 doi: 10.1038/nrendo.2017.180. PMID: 29393299
Wijdicks EF, Bamlet WR, Maramattom BV, Manno EM, McClelland RL
Ann Neurol 2005 Oct;58(4):585-93. doi: 10.1002/ana.20611. PMID: 16178024
Wahlund LO, Barkhof F, Fazekas F, Bronge L, Augustin M, Sjögren M, Wallin A, Ader H, Leys D, Pantoni L, Pasquier F, Erkinjuntti T, Scheltens P; European Task Force on Age-Related White Matter Changes
Stroke 2001 Jun;32(6):1318-22. doi: 10.1161/01.str.32.6.1318. PMID: 11387493

Recent systematic reviews

Lepri B, Romani D, Storari L, Barbari V
Int J Environ Res Public Health 2023 Feb 24;20(5) doi: 10.3390/ijerph20054098. PMID: 36901108Free PMC Article
Chong PLH, Garic D, Shen MD, Lundgaard I, Schwichtenberg AJ
Sleep Med Rev 2022 Feb;61:101572. Epub 2021 Nov 18 doi: 10.1016/j.smrv.2021.101572. PMID: 34902819Free PMC Article
Tiseo C, Vacca A, Felbush A, Filimonova T, Gai A, Glazyrina T, Hubalek IA, Marchenko Y, Overeem LH, Piroso S, Tkachev A, Martelletti P, Sacco S; European Headache Federation School of Advanced Studies (EHF-SAS)
J Headache Pain 2020 Oct 27;21(1):126. doi: 10.1186/s10194-020-01192-5. PMID: 33109076Free PMC Article
Tabrizi R, Saneei P, Lankarani KB, Akbari M, Kolahdooz F, Esmaillzadeh A, Nadi-Ravandi S, Mazoochi M, Asemi Z
Crit Rev Food Sci Nutr 2019;59(16):2688-2696. Epub 2018 Oct 18 doi: 10.1080/10408398.2018.1507996. PMID: 30335479
Beghi E, Carpio A, Forsgren L, Hesdorffer DC, Malmgren K, Sander JW, Tomson T, Hauser WA
Epilepsia 2010 Apr;51(4):671-5. Epub 2009 Sep 3 doi: 10.1111/j.1528-1167.2009.02285.x. PMID: 19732133

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