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Conjunctival nevus

MedGen UID:
83422
•Concept ID:
C0346363
•
Neoplastic Process
Synonyms: Conjunctival Nevus; conjunctival nevus; Nevus of conjunctiva; Nevus of Conjunctiva; Nevus of the Conjunctiva; Nevus of the conjunctiva
SNOMED CT: Nevus of conjunctiva (255006004)
 
Monarch Initiative: MONDO:0006172

Definition

A benign melanocytic nevus that arises from the conjunctiva. [from NCI]

Professional guidelines

PubMed

Evaluation and management of benign tumors of the eye and eyelid.
Brown R, Fard S, Feng P, Kerr PE
Clin Dermatol 2024 Jul-Aug;42(4):343-350. Epub 2024 Jan 26 doi: 10.1016/j.clindermatol.2024.01.005. PMID: 38281689

Recent clinical studies

Therapy

Adopting low-shot deep learning for the detection of conjunctival melanoma using ocular surface images.
Yoo TK, Choi JY, Kim HK, Ryu IH, Kim JK
Comput Methods Programs Biomed 2021 Jun;205:106086. Epub 2021 Apr 3 doi: 10.1016/j.cmpb.2021.106086. PMID: 33862570
Efficacy of Pattern Scan Laser photocoagulation for superficial conjunctival nevi ablation.
Park YM, Lee JE, Lee JS
Lasers Med Sci 2016 Jul;31(5):1037-9. Epub 2016 Feb 25 doi: 10.1007/s10103-016-1915-x. PMID: 26914686
Ocular morbidity among primary school children of Dhulikhel, Nepal.
Sherpa D, Panta CR, Joshi N
Nepal J Ophthalmol 2011 Jul-Dec;3(2):172-6. doi: 10.3126/nepjoph.v3i2.5272. PMID: 21876593
Reconstruction of the ocular surface by transplantation of a serum-free derived cultivated conjunctival epithelial equivalent.
Tan DT, Ang LP, Beuerman RW
Transplantation 2004 Jun 15;77(11):1729-34. doi: 10.1097/01.tp.0000127593.65888.a6. PMID: 15201674

Prognosis

Incidence and clinical characteristics of pediatric ocular tumors in a Midwestern US population.
Wang KY, Xu TT, White LJ, Hodge DO, Dalvin LA
J AAPOS 2023 Aug;27(4):189.e1-189.e5. Epub 2023 Jul 13 doi: 10.1016/j.jaapos.2023.05.007. PMID: 37453664Free PMC Article
Conjunctival Autografts for Ocular Surface Reconstruction after Conjunctival Nevus Excision.
Ucar F
Cornea 2023 Oct 1;42(10):1206-1210. Epub 2022 Sep 28 doi: 10.1097/ICO.0000000000003117. PMID: 36731062
Indocyanine Green Angiographic Assessment of Conjunctival Melanocytic Disorders.
Palme C, Wanner A, Romano V, Franchi A, Haas G, Kaye SB, Steger B
Cornea 2021 Dec 1;40(12):1519-1524. doi: 10.1097/ICO.0000000000002681. PMID: 33591034
Conjunctival nevi and melanoma: multiparametric immunohistochemical analysis, including p16, SOX10, HMB45, and Ki-67.
Milman T, Zhang Q, Ang S, Elder D, Ida CM, Salomao DR, Lally SE, Shields JA, Hamershock RA, Sioufi K, Shields CL, Eagle RC Jr
Hum Pathol 2020 Sep;103:107-119. Epub 2020 Jul 21 doi: 10.1016/j.humpath.2020.07.020. PMID: 32707054
Giant conjunctival nevus: clinical features and natural course in 32 cases.
Shields CL, Regillo AC, Mellen PL, Kaliki S, Lally SE, Shields JA
JAMA Ophthalmol 2013 Jul;131(7):857-63. doi: 10.1001/jamaophthalmol.2013.160. PMID: 23702735

Clinical prediction guides

Factors affecting recurrence and metastasis in conjunctival melanoma.
Çalış Karanfil F, Gündüz AK, Gündüz ÖÖ, Özalp Ateş FS
Int Ophthalmol 2023 Nov;43(11):4203-4215. Epub 2023 Aug 28 doi: 10.1007/s10792-023-02830-y. PMID: 37639080
Conjunctival Autografts for Ocular Surface Reconstruction after Conjunctival Nevus Excision.
Ucar F
Cornea 2023 Oct 1;42(10):1206-1210. Epub 2022 Sep 28 doi: 10.1097/ICO.0000000000003117. PMID: 36731062
Progress of Bulbar Conjunctival Microcirculation Alterations in the Diagnosis of Ocular Diseases.
Sun Z, Li Y, Liu R, Ma B, Zhou Y, Duan H, Bian L, Li W, Qi H
Dis Markers 2022;2022:4046809. Epub 2022 Aug 28 doi: 10.1155/2022/4046809. PMID: 36072898Free PMC Article
Clinical and immunohistopathological study of conjunctival melanocytic lesions in pediatric and adolescent patients. A case series.
Bogdănici CM, Costea CF, Dumitrescu GF, Sava A, Ciobanu Apostol DG, Scripcariu DV, Nicoară SD, Tănase DM, Andriescu EC, Cărăuleanu A, Danciu M, Sălăvăstru SC, Schmitzer S, Cucu AI, Niagu IA
Rom J Morphol Embryol 2021 Oct-Dec;62(4):907-915. doi: 10.47162/RJME.62.4.03. PMID: 35673810Free PMC Article
Conjunctival nevi and melanoma: multiparametric immunohistochemical analysis, including p16, SOX10, HMB45, and Ki-67.
Milman T, Zhang Q, Ang S, Elder D, Ida CM, Salomao DR, Lally SE, Shields JA, Hamershock RA, Sioufi K, Shields CL, Eagle RC Jr
Hum Pathol 2020 Sep;103:107-119. Epub 2020 Jul 21 doi: 10.1016/j.humpath.2020.07.020. PMID: 32707054

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