U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Villous adenoma

MedGen UID:
60206
•Concept ID:
C0206674
•
Neoplastic Process
Synonyms: Adenoma, Villous; Adenomas, Villous; Villous Adenoma; Villous Adenomas
SNOMED CT: Villous papilloma (128859003); Villous adenoma (128859003)
 
Monarch Initiative: MONDO:0000502

Definition

An adenoma arising from the glandular epithelium of the gastrointestinal tract. It is characterized by the presence of a villous architectural pattern. Most often it occurs in the large intestine, small intestine, and the stomach. The neoplastic epithelial cells show dysplastic features. [from NCI]

Professional guidelines

PubMed

Double balloon enteroscopy in children: diagnosis, treatment, and safety.
Thomson M, Venkatesh K, Elmalik K, van der Veer W, Jaacobs M
World J Gastroenterol 2010 Jan 7;16(1):56-62. doi: 10.3748/wjg.v16.i1.56. PMID: 20039449Free PMC Article
Intraperitoneal chemotherapy for peritoneal carcinomatosis from colonic or appendiceal cystadenocarcinoma: rationale and results of treatment.
Sugarbaker PH, Landy D, Pascal R
Prog Clin Biol Res 1990;354B:141-70. PMID: 2236162
Duodenal polyps: diagnosis and management.
Reddy RR, Schuman BM, Priest RJ
J Clin Gastroenterol 1981 Jun;3(2):139-47. doi: 10.1097/00004836-198106000-00007. PMID: 7240690

Recent clinical studies

Etiology

Association between Helicobacter pylori infection and colorectal polyps.
Basmaci N, Karataş A, Ergin M, Dumlu GŞ
Medicine (Baltimore) 2023 Oct 20;102(42):e35591. doi: 10.1097/MD.0000000000035591. PMID: 37861565Free PMC Article
Colorectal dysplasia in chronic inflammatory bowel disease: a contemporary consensus classification and interobserver study.
Harpaz N, Goldblum JR, Shepherd NA, Riddell RH, Rubio CA, Vieth M, Wang HH, Odze RD
Hum Pathol 2023 Aug;138:49-61. Epub 2023 May 27 doi: 10.1016/j.humpath.2023.05.008. PMID: 37247824
Precursor lesions of the urinary bladder.
McKenney JK
Histopathology 2019 Jan;74(1):68-76. doi: 10.1111/his.13762. PMID: 30565304
Clonality of combined tumors.
Huang J, Behrens C, Wistuba II, Gazdar AF, Jagirdar J
Arch Pathol Lab Med 2002 Apr;126(4):437-41. doi: 10.5858/2002-126-0437-COCT. PMID: 11900568
Colonic polyps.
Ackroyd FW, Hedberg SE
Annu Rev Med 1985;36:619-25. doi: 10.1146/annurev.me.36.020185.003155. PMID: 3994327

Diagnosis

Precursor lesions of the urinary bladder.
McKenney JK
Histopathology 2019 Jan;74(1):68-76. doi: 10.1111/his.13762. PMID: 30565304
The third pathway of colorectal carcinogenesis.
Rubio CA, Puppa G, de Petris G, Kis L, Schmidt PT
J Clin Pathol 2018 Jan;71(1):7-11. Epub 2017 Jul 27 doi: 10.1136/jclinpath-2017-204660. PMID: 28751521
Rectal pseudodiverticulum.
Singh S, Savage L
BMJ Case Rep 2014 Jul 8;2014 doi: 10.1136/bcr-2013-201888. PMID: 25006050Free PMC Article
Magnification chromo-colonoscopy.
Togashi K, Konishi F
ANZ J Surg 2006 Dec;76(12):1101-5. doi: 10.1111/j.1445-2197.2006.03933.x. PMID: 17199698
Colonic polyps.
Ackroyd FW, Hedberg SE
Annu Rev Med 1985;36:619-25. doi: 10.1146/annurev.me.36.020185.003155. PMID: 3994327

Therapy

Colorectal dysplasia in chronic inflammatory bowel disease: a contemporary consensus classification and interobserver study.
Harpaz N, Goldblum JR, Shepherd NA, Riddell RH, Rubio CA, Vieth M, Wang HH, Odze RD
Hum Pathol 2023 Aug;138:49-61. Epub 2023 May 27 doi: 10.1016/j.humpath.2023.05.008. PMID: 37247824
Rectal pseudodiverticulum.
Singh S, Savage L
BMJ Case Rep 2014 Jul 8;2014 doi: 10.1136/bcr-2013-201888. PMID: 25006050Free PMC Article
Laparoscopic total mesorectal excision (TME) for rectal cancer surgery: long-term outcomes.
Leroy J, Jamali F, Forbes L, Smith M, Rubino F, Mutter D, Marescaux J
Surg Endosc 2004 Feb;18(2):281-9. Epub 2003 Dec 29 doi: 10.1007/s00464-002-8877-8. PMID: 14691716
In situ adenocarcinoma of the bladder.
Chan TY, Epstein JI
Am J Surg Pathol 2001 Jul;25(7):892-9. doi: 10.1097/00000478-200107000-00007. PMID: 11420460
Experience with the use of the circular stapler in rectal surgery.
Kyzer S, Gordon PH
Dis Colon Rectum 1992 Jul;35(7):696-706. doi: 10.1007/BF02053764. PMID: 1611960

Prognosis

Gastric villous adenoma: a case report and review of the literature.
Sathirawich P, Pongpaibul A, Parakonthun T, Kaosombatwattana U
J Med Case Rep 2023 Apr 26;17(1):167. doi: 10.1186/s13256-023-03893-2. PMID: 37098577Free PMC Article
Giant villous adenoma of rectum- what is the malignant potential and what is the optimal treatment? A case and review of literature.
Bains L, Lal P, Vindal A, Singh M
World J Surg Oncol 2019 Jun 25;17(1):109. doi: 10.1186/s12957-019-1650-4. PMID: 31238922Free PMC Article
Magnification chromo-colonoscopy.
Togashi K, Konishi F
ANZ J Surg 2006 Dec;76(12):1101-5. doi: 10.1111/j.1445-2197.2006.03933.x. PMID: 17199698
Pancreas-sparing duodenectomy: technique and indications.
Lundell L, Hyltander A, Liedman B
Eur J Surg 2002;168(2):74-7. doi: 10.1080/11024150252884278. PMID: 12113274
Colonic polyps.
Ackroyd FW, Hedberg SE
Annu Rev Med 1985;36:619-25. doi: 10.1146/annurev.me.36.020185.003155. PMID: 3994327

Clinical prediction guides

Association between Helicobacter pylori infection and colorectal polyps.
Basmaci N, Karataş A, Ergin M, Dumlu GŞ
Medicine (Baltimore) 2023 Oct 20;102(42):e35591. doi: 10.1097/MD.0000000000035591. PMID: 37861565Free PMC Article
Villous Adenoma Arising in the Urethra of a Female with Bladder Augmentation History: A Case Report and Review of the Literature.
Demir H, Cin S, Citgez S, Uygun N
Turk Patoloji Derg 2021;37(2):161-166. doi: 10.5146/tjpath.2020.01502. PMID: 32779155Free PMC Article
Reliability in villous tumors staging between preoperative MRI and histopathological examination.
Vogrig C, Leclerc J, Haghnejad V, Orry X, Remen T, Germain A, Laurent V
Abdom Radiol (NY) 2020 Oct;45(10):3046-3056. doi: 10.1007/s00261-020-02450-5. PMID: 32123949
Updates in the Pathologic Diagnosis and Classification of Epithelial Neoplasms of Urachal Origin.
Paner GP, Lopez-Beltran A, Sirohi D, Amin MB
Adv Anat Pathol 2016 Mar;23(2):71-83. doi: 10.1097/PAP.0000000000000110. PMID: 26849813
Magnification chromo-colonoscopy.
Togashi K, Konishi F
ANZ J Surg 2006 Dec;76(12):1101-5. doi: 10.1111/j.1445-2197.2006.03933.x. PMID: 17199698

Recent systematic reviews

Incidence of advanced adenomas at surveillance colonoscopy in patients with a personal history of colon adenomas: a meta-analysis and systematic review.
Saini SD, Kim HM, Schoenfeld P
Gastrointest Endosc 2006 Oct;64(4):614-26. doi: 10.1016/j.gie.2006.06.057. PMID: 16996358
Endorectal ultrasound detection of focal carcinoma within rectal adenomas.
Worrell S, Horvath K, Blakemore T, Flum D
Am J Surg 2004 May;187(5):625-9; discussion 629. doi: 10.1016/j.amjsurg.2004.01.005. PMID: 15135679

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...