U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Sedated

MedGen UID:
536362
•Concept ID:
C0235195
•
Finding
Synonyms: Sedation; Under sedation
SNOMED CT: Under sedation (17971005); Sedated (17971005)

Definition

A state of a lowered level of consciousness. [from NCI]

Professional guidelines

PubMed

Feasibility and clinical utility of transvenous intracardiac echocardiography in conscious, sedated horses.
Boutet BG, Gordon SG, De Solis CN, Lepiz MA, Saunders AB, Wesselowski S
J Vet Cardiol 2022 Aug;42:15-22. Epub 2022 May 11 doi: 10.1016/j.jvc.2022.05.002. PMID: 35662025
Laryngeal mask versus facemask in the respiratory management during catheter ablation.
Koyama T, Kobayashi M, Ichikawa T, Wakabayashi Y, Toma D, Abe H
BMC Anesthesiol 2020 Jan 7;20(1):9. doi: 10.1186/s12871-019-0924-2. PMID: 31910797Free PMC Article
Seizures and hypothermia: importance of electroencephalographic monitoring and considerations for treatment.
Boylan GB, Kharoshankaya L, Wusthoff CJ
Semin Fetal Neonatal Med 2015 Apr;20(2):103-8. Epub 2015 Feb 14 doi: 10.1016/j.siny.2015.01.001. PMID: 25683598

Recent clinical studies

Etiology

A randomized, controlled clinical trial comparing remimazolam to propofol when combined with alfentanil for sedation during ERCP procedures.
Dong SA, Guo Y, Liu SS, Wu LL, Wu LN, Song K, Wang JH, Chen HR, Li WZ, Li HX, Zhang L, Yu JB
J Clin Anesth 2023 Jun;86:111077. Epub 2023 Feb 9 doi: 10.1016/j.jclinane.2023.111077. PMID: 36764022
Magnetic resonance imaging in children with implants.
Jaimes C, Biaggotti D, Sreedher G, Chaturvedi A, Moore MM, Danehy AR
Pediatr Radiol 2021 May;51(5):748-759. Epub 2021 Apr 19 doi: 10.1007/s00247-021-04965-5. PMID: 33871727
Palliative pharmacological sedation for terminally ill adults.
Beller EM, van Driel ML, McGregor L, Truong S, Mitchell G
Cochrane Database Syst Rev 2015 Jan 2;1(1):CD010206. doi: 10.1002/14651858.CD010206.pub2. PMID: 25879099Free PMC Article
Colonoscopy without sedation.
Yörük G, Aksöz K, Unsal B, Buyraç Z, Buran T, Yazicioğlu N, Yildiz C, Yalçin HC
Turk J Gastroenterol 2003 Mar;14(1):59-63. PMID: 14593540
Assessing pain in critically ill sedated patients by using a behavioral pain scale.
Payen JF, Bru O, Bosson JL, Lagrasta A, Novel E, Deschaux I, Lavagne P, Jacquot C
Crit Care Med 2001 Dec;29(12):2258-63. doi: 10.1097/00003246-200112000-00004. PMID: 11801819

Diagnosis

Reverse triggering during mechanical ventilation: Diagnosis and clinical implications.
Núñez Silveira JM, Gallardo A, García-Valdés P, Ríos F, Rodriguez PO, Felipe Damiani L
Med Intensiva (Engl Ed) 2023 Nov;47(11):648-657. Epub 2023 Oct 20 doi: 10.1016/j.medine.2023.10.009. PMID: 37867118
Pseudotumor Cerebri Syndrome in Children.
Barmherzig R, Szperka CL
Curr Pain Headache Rep 2019 Jul 10;23(8):58. doi: 10.1007/s11916-019-0795-8. PMID: 31292773Free PMC Article
Septic Encephalopathy.
Robba C, Crippa IA, Taccone FS
Curr Neurol Neurosci Rep 2018 Oct 2;18(12):82. doi: 10.1007/s11910-018-0895-6. PMID: 30280261
Anesthesia in swine : optimizing a laboratory model to optimize translational research.
Pehböck D, Dietrich H, Klima G, Paal P, Lindner KH, Wenzel V
Anaesthesist 2015 Jan;64(1):65-70. doi: 10.1007/s00101-014-2371-2. PMID: 25384955
Evolving techniques in colonoscopy.
Vemulapalli KC, Rex DK
Curr Opin Gastroenterol 2011 Sep;27(5):430-8. doi: 10.1097/MOG.0b013e328349cfc0. PMID: 21785352

Therapy

Dexmedetomidine and Propofol Sedation in Critically Ill Patients and Dose-associated 90-Day Mortality: A Secondary Cohort Analysis of a Randomized Controlled Trial (SPICE III).
Shehabi Y, Serpa Neto A, Bellomo R, Howe BD, Arabi YM, Bailey M, Bass FE, Bin Kadiman S, McArthur CJ, Reade MC, Seppelt IM, Takala J, Wise MP, Webb SA; SPICE III Study Investigators
Am J Respir Crit Care Med 2023 Apr 1;207(7):876-886. doi: 10.1164/rccm.202206-1208OC. PMID: 36215171
Nonsedation or Light Sedation in Critically Ill, Mechanically Ventilated Patients.
Olsen HT, Nedergaard HK, Strøm T, Oxlund J, Wian KA, Ytrebø LM, Kroken BA, Chew M, Korkmaz S, Lauridsen JT, Toft P
N Engl J Med 2020 Mar 19;382(12):1103-1111. Epub 2020 Feb 16 doi: 10.1056/NEJMoa1906759. PMID: 32068366
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Shehabi Y, Howe BD, Bellomo R, Arabi YM, Bailey M, Bass FE, Bin Kadiman S, McArthur CJ, Murray L, Reade MC, Seppelt IM, Takala J, Wise MP, Webb SA; ANZICS Clinical Trials Group and the SPICE III Investigators
N Engl J Med 2019 Jun 27;380(26):2506-2517. Epub 2019 May 19 doi: 10.1056/NEJMoa1904710. PMID: 31112380
Non-pharmacological interventions for assisting the induction of anaesthesia in children.
Manyande A, Cyna AM, Yip P, Chooi C, Middleton P
Cochrane Database Syst Rev 2015 Jul 14;2015(7):CD006447. doi: 10.1002/14651858.CD006447.pub3. PMID: 26171895Free PMC Article
Palliative pharmacological sedation for terminally ill adults.
Beller EM, van Driel ML, McGregor L, Truong S, Mitchell G
Cochrane Database Syst Rev 2015 Jan 2;1(1):CD010206. doi: 10.1002/14651858.CD010206.pub2. PMID: 25879099Free PMC Article

Prognosis

Brainstem dysfunction in critically ill patients.
Benghanem S, Mazeraud A, Azabou E, Chhor V, Shinotsuka CR, Claassen J, Rohaut B, Sharshar T
Crit Care 2020 Jan 6;24(1):5. doi: 10.1186/s13054-019-2718-9. PMID: 31907011Free PMC Article
Pseudotumor Cerebri Syndrome in Children.
Barmherzig R, Szperka CL
Curr Pain Headache Rep 2019 Jul 10;23(8):58. doi: 10.1007/s11916-019-0795-8. PMID: 31292773Free PMC Article
Heart rate variability: implications for perioperative anesthesia care.
Anderson TA
Curr Opin Anaesthesiol 2017 Dec;30(6):691-697. doi: 10.1097/ACO.0000000000000530. PMID: 28957877
Anaesthetic management of sleep-disordered breathing in adults.
Hillman DR, Chung F
Respirology 2017 Feb;22(2):230-239. Epub 2016 Dec 17 doi: 10.1111/resp.12967. PMID: 27988979
Is the type of insufflation a key issue in gastro-intestinal endoscopy?
Lord AC, Riss S
World J Gastroenterol 2014 Mar 7;20(9):2193-9. doi: 10.3748/wjg.v20.i9.2193. PMID: 24605018Free PMC Article

Clinical prediction guides

Comparison of remimazolam-based and propofol-based total intravenous anesthesia on postoperative quality of recovery: A randomized non-inferiority trial.
Choi JY, Lee HS, Kim JY, Han DW, Yang JY, Kim MJ, Song Y
J Clin Anesth 2022 Nov;82:110955. Epub 2022 Aug 25 doi: 10.1016/j.jclinane.2022.110955. PMID: 36029704
Palliative pharmacological sedation for terminally ill adults.
Beller EM, van Driel ML, McGregor L, Truong S, Mitchell G
Cochrane Database Syst Rev 2015 Jan 2;1(1):CD010206. doi: 10.1002/14651858.CD010206.pub2. PMID: 25879099Free PMC Article
Is the type of insufflation a key issue in gastro-intestinal endoscopy?
Lord AC, Riss S
World J Gastroenterol 2014 Mar 7;20(9):2193-9. doi: 10.3748/wjg.v20.i9.2193. PMID: 24605018Free PMC Article
Colonoscopy without sedation.
Yörük G, Aksöz K, Unsal B, Buyraç Z, Buran T, Yazicioğlu N, Yildiz C, Yalçin HC
Turk J Gastroenterol 2003 Mar;14(1):59-63. PMID: 14593540
Assessing pain in critically ill sedated patients by using a behavioral pain scale.
Payen JF, Bru O, Bosson JL, Lagrasta A, Novel E, Deschaux I, Lavagne P, Jacquot C
Crit Care Med 2001 Dec;29(12):2258-63. doi: 10.1097/00003246-200112000-00004. PMID: 11801819

Recent systematic reviews

Effect of inhaled anaesthetics on cognitive and psychiatric outcomes in critically ill adults: a systematic review and meta-analysis.
Cuninghame S, Jerath A, Gorsky K, Sivajohan A, Francoeur C, Withington D, Burry L, Cuthbertson BH, Orser BA, Martin C, Owen AM, Slessarev M; Sedating with Volatile Anesthetics Critically Ill COVID-19 Patients in ICU: Effects on Ventilatory Parameters and Survival study investigators
Br J Anaesth 2023 Aug;131(2):314-327. Epub 2023 Jun 19 doi: 10.1016/j.bja.2023.05.004. PMID: 37344338
Fundamentals and innovations in regional anaesthesia for infants and children.
Heydinger G, Tobias J, Veneziano G
Anaesthesia 2021 Jan;76 Suppl 1:74-88. doi: 10.1111/anae.15283. PMID: 33426659
A systematic review of capnography for sedation.
Conway A, Douglas C, Sutherland JR
Anaesthesia 2016 Apr;71(4):450-4. Epub 2016 Jan 21 doi: 10.1111/anae.13378. PMID: 26792775
Non-pharmacological interventions for assisting the induction of anaesthesia in children.
Manyande A, Cyna AM, Yip P, Chooi C, Middleton P
Cochrane Database Syst Rev 2015 Jul 14;2015(7):CD006447. doi: 10.1002/14651858.CD006447.pub3. PMID: 26171895Free PMC Article
Palliative pharmacological sedation for terminally ill adults.
Beller EM, van Driel ML, McGregor L, Truong S, Mitchell G
Cochrane Database Syst Rev 2015 Jan 2;1(1):CD010206. doi: 10.1002/14651858.CD010206.pub2. PMID: 25879099Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...