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Vesicoureteral reflux 6(VUR6)

MedGen UID:
482071
Concept ID:
C3280441
Disease or Syndrome
Synonym: VUR6
 
Monarch Initiative: MONDO:0013684
OMIM®: 614319

Professional guidelines

PubMed

Buettcher M, Trueck J, Niederer-Loher A, Heininger U, Agyeman P, Asner S, Berger C, Bielicki J, Kahlert C, Kottanattu L, Meyer Sauteur PM, Paioni P, Posfay-Barbe K, Relly C, Ritz N, Zimmermann P, Zucol F, Gobet R, Shavit S, Rudin C, Laube G, von Vigier R, Neuhaus TJ
Eur J Pediatr 2021 Mar;180(3):663-674. Epub 2020 Jul 3 doi: 10.1007/s00431-020-03714-4. PMID: 32621135Free PMC Article
Miyakita H, Hayashi Y, Mitsui T, Okawada M, Kinoshita Y, Kimata T, Koikawa Y, Sakai K, Satoh H, Tokunaga M, Naitoh Y, Niimura F, Matsuoka H, Mizuno K, Kaneko K, Kubota M
Int J Urol 2020 Jun;27(6):480-490. Epub 2020 Apr 1 doi: 10.1111/iju.14223. PMID: 32239562Free PMC Article
Subcommittee on Urinary Tract Infection, Steering Committee on Quality Improvement and Management, Roberts KB
Pediatrics 2011 Sep;128(3):595-610. Epub 2011 Aug 28 doi: 10.1542/peds.2011-1330. PMID: 21873693

Recent clinical studies

Etiology

Faris A, Lane GI, Mehra R, Dadhania V, Crescenze I, Clemens JQ, Romo PB, Stoffel J, Malaeb B, Blair Y, Goh M, Gupta P, Cameron AP
Neurourol Urodyn 2023 Aug;42(6):1194-1202. Epub 2023 May 1 doi: 10.1002/nau.25195. PMID: 37126389
Mattoo TK, Mohammad D
Pediatr Clin North Am 2022 Dec;69(6):1115-1129. Epub 2022 Oct 29 doi: 10.1016/j.pcl.2022.07.007. PMID: 36880925
Rius-Gordillo N, Ferré N, González JD, Ibars Z, Parada-Ricart E, Fraga MG, Chocron S, Samper M, Vicente C, Fuertes J, Escribano J; DEXCAR Study Group
Pediatr Nephrol 2022 Sep;37(9):2109-2118. Epub 2022 Jan 18 doi: 10.1007/s00467-021-05398-w. PMID: 35041042Free PMC Article
Miyakita H, Hayashi Y, Mitsui T, Okawada M, Kinoshita Y, Kimata T, Koikawa Y, Sakai K, Satoh H, Tokunaga M, Naitoh Y, Niimura F, Matsuoka H, Mizuno K, Kaneko K, Kubota M
Int J Urol 2020 Jun;27(6):480-490. Epub 2020 Apr 1 doi: 10.1111/iju.14223. PMID: 32239562Free PMC Article
Cara-Fuentes G, Gupta N, Garin EH
Pediatr Nephrol 2015 May;30(5):703-6. Epub 2014 Dec 11 doi: 10.1007/s00467-014-3021-2. PMID: 25503325

Diagnosis

Mattoo TK, Mohammad D
Pediatr Clin North Am 2022 Dec;69(6):1115-1129. Epub 2022 Oct 29 doi: 10.1016/j.pcl.2022.07.007. PMID: 36880925
Miyakita H, Hayashi Y, Mitsui T, Okawada M, Kinoshita Y, Kimata T, Koikawa Y, Sakai K, Satoh H, Tokunaga M, Naitoh Y, Niimura F, Matsuoka H, Mizuno K, Kaneko K, Kubota M
Int J Urol 2020 Jun;27(6):480-490. Epub 2020 Apr 1 doi: 10.1111/iju.14223. PMID: 32239562Free PMC Article
Keren R, Shaikh N, Pohl H, Gravens-Mueller L, Ivanova A, Zaoutis L, Patel M, deBerardinis R, Parker A, Bhatnagar S, Haralam MA, Pope M, Kearney D, Sprague B, Barrera R, Viteri B, Egigueron M, Shah N, Hoberman A
Pediatrics 2015 Jul;136(1):e13-21. Epub 2015 Jun 8 doi: 10.1542/peds.2015-0409. PMID: 26055855Free PMC Article
Subcommittee on Urinary Tract Infection, Steering Committee on Quality Improvement and Management, Roberts KB
Pediatrics 2011 Sep;128(3):595-610. Epub 2011 Aug 28 doi: 10.1542/peds.2011-1330. PMID: 21873693
Cendron M
J Pediatr Urol 2008 Dec;4(6):414-21. Epub 2008 Sep 4 doi: 10.1016/j.jpurol.2008.04.009. PMID: 18775677

Therapy

Morello W, Baskin E, Jankauskiene A, Yalcinkaya F, Zurowska A, Puccio G, Serafinelli J, La Manna A, Krzemień G, Pennesi M, La Scola C, Becherucci F, Brugnara M, Yuksel S, Mekahli D, Chimenz R, De Palma D, Zucchetta P, Vajauskas D, Drozdz D, Szczepanska M, Caliskan S, Lombet J, Minoli DG, Guarino S, Gulleroglu K, Ruzgiene D, Szmigielska A, Barbi E, Ozcakar ZB, Kranz A, Pasini A, Materassi M, De Rechter S, Ariceta G, Weber LT, Marzuillo P, Alberici I, Taranta-Janusz K, Caldas Afonso A, Tkaczyk M, Català M, Cabrera Sevilla JE, Mehls O, Schaefer F, Montini G; PREDICT Study Group
N Engl J Med 2023 Sep 14;389(11):987-997. Epub 2023 Sep 12 doi: 10.1056/NEJMoa2300161. PMID: 37702442
Rius-Gordillo N, Ferré N, González JD, Ibars Z, Parada-Ricart E, Fraga MG, Chocron S, Samper M, Vicente C, Fuertes J, Escribano J; DEXCAR Study Group
Pediatr Nephrol 2022 Sep;37(9):2109-2118. Epub 2022 Jan 18 doi: 10.1007/s00467-021-05398-w. PMID: 35041042Free PMC Article
Williams G, Craig JC
Cochrane Database Syst Rev 2019 Apr 1;4(4):CD001534. doi: 10.1002/14651858.CD001534.pub4. PMID: 30932167Free PMC Article
Keren R, Shaikh N, Pohl H, Gravens-Mueller L, Ivanova A, Zaoutis L, Patel M, deBerardinis R, Parker A, Bhatnagar S, Haralam MA, Pope M, Kearney D, Sprague B, Barrera R, Viteri B, Egigueron M, Shah N, Hoberman A
Pediatrics 2015 Jul;136(1):e13-21. Epub 2015 Jun 8 doi: 10.1542/peds.2015-0409. PMID: 26055855Free PMC Article
Subcommittee on Urinary Tract Infection, Steering Committee on Quality Improvement and Management, Roberts KB
Pediatrics 2011 Sep;128(3):595-610. Epub 2011 Aug 28 doi: 10.1542/peds.2011-1330. PMID: 21873693

Prognosis

Morello W, Baskin E, Jankauskiene A, Yalcinkaya F, Zurowska A, Puccio G, Serafinelli J, La Manna A, Krzemień G, Pennesi M, La Scola C, Becherucci F, Brugnara M, Yuksel S, Mekahli D, Chimenz R, De Palma D, Zucchetta P, Vajauskas D, Drozdz D, Szczepanska M, Caliskan S, Lombet J, Minoli DG, Guarino S, Gulleroglu K, Ruzgiene D, Szmigielska A, Barbi E, Ozcakar ZB, Kranz A, Pasini A, Materassi M, De Rechter S, Ariceta G, Weber LT, Marzuillo P, Alberici I, Taranta-Janusz K, Caldas Afonso A, Tkaczyk M, Català M, Cabrera Sevilla JE, Mehls O, Schaefer F, Montini G; PREDICT Study Group
N Engl J Med 2023 Sep 14;389(11):987-997. Epub 2023 Sep 12 doi: 10.1056/NEJMoa2300161. PMID: 37702442
Rius-Gordillo N, Ferré N, González JD, Ibars Z, Parada-Ricart E, Fraga MG, Chocron S, Samper M, Vicente C, Fuertes J, Escribano J; DEXCAR Study Group
Pediatr Nephrol 2022 Sep;37(9):2109-2118. Epub 2022 Jan 18 doi: 10.1007/s00467-021-05398-w. PMID: 35041042Free PMC Article
Miyakita H, Hayashi Y, Mitsui T, Okawada M, Kinoshita Y, Kimata T, Koikawa Y, Sakai K, Satoh H, Tokunaga M, Naitoh Y, Niimura F, Matsuoka H, Mizuno K, Kaneko K, Kubota M
Int J Urol 2020 Jun;27(6):480-490. Epub 2020 Apr 1 doi: 10.1111/iju.14223. PMID: 32239562Free PMC Article
Keren R, Shaikh N, Pohl H, Gravens-Mueller L, Ivanova A, Zaoutis L, Patel M, deBerardinis R, Parker A, Bhatnagar S, Haralam MA, Pope M, Kearney D, Sprague B, Barrera R, Viteri B, Egigueron M, Shah N, Hoberman A
Pediatrics 2015 Jul;136(1):e13-21. Epub 2015 Jun 8 doi: 10.1542/peds.2015-0409. PMID: 26055855Free PMC Article
Subcommittee on Urinary Tract Infection, Steering Committee on Quality Improvement and Management, Roberts KB
Pediatrics 2011 Sep;128(3):595-610. Epub 2011 Aug 28 doi: 10.1542/peds.2011-1330. PMID: 21873693

Clinical prediction guides

Morello W, Baskin E, Jankauskiene A, Yalcinkaya F, Zurowska A, Puccio G, Serafinelli J, La Manna A, Krzemień G, Pennesi M, La Scola C, Becherucci F, Brugnara M, Yuksel S, Mekahli D, Chimenz R, De Palma D, Zucchetta P, Vajauskas D, Drozdz D, Szczepanska M, Caliskan S, Lombet J, Minoli DG, Guarino S, Gulleroglu K, Ruzgiene D, Szmigielska A, Barbi E, Ozcakar ZB, Kranz A, Pasini A, Materassi M, De Rechter S, Ariceta G, Weber LT, Marzuillo P, Alberici I, Taranta-Janusz K, Caldas Afonso A, Tkaczyk M, Català M, Cabrera Sevilla JE, Mehls O, Schaefer F, Montini G; PREDICT Study Group
N Engl J Med 2023 Sep 14;389(11):987-997. Epub 2023 Sep 12 doi: 10.1056/NEJMoa2300161. PMID: 37702442
Rius-Gordillo N, Ferré N, González JD, Ibars Z, Parada-Ricart E, Fraga MG, Chocron S, Samper M, Vicente C, Fuertes J, Escribano J; DEXCAR Study Group
Pediatr Nephrol 2022 Sep;37(9):2109-2118. Epub 2022 Jan 18 doi: 10.1007/s00467-021-05398-w. PMID: 35041042Free PMC Article
Miyakita H, Hayashi Y, Mitsui T, Okawada M, Kinoshita Y, Kimata T, Koikawa Y, Sakai K, Satoh H, Tokunaga M, Naitoh Y, Niimura F, Matsuoka H, Mizuno K, Kaneko K, Kubota M
Int J Urol 2020 Jun;27(6):480-490. Epub 2020 Apr 1 doi: 10.1111/iju.14223. PMID: 32239562Free PMC Article
Keren R, Shaikh N, Pohl H, Gravens-Mueller L, Ivanova A, Zaoutis L, Patel M, deBerardinis R, Parker A, Bhatnagar S, Haralam MA, Pope M, Kearney D, Sprague B, Barrera R, Viteri B, Egigueron M, Shah N, Hoberman A
Pediatrics 2015 Jul;136(1):e13-21. Epub 2015 Jun 8 doi: 10.1542/peds.2015-0409. PMID: 26055855Free PMC Article
Cara-Fuentes G, Gupta N, Garin EH
Pediatr Nephrol 2015 May;30(5):703-6. Epub 2014 Dec 11 doi: 10.1007/s00467-014-3021-2. PMID: 25503325

Recent systematic reviews

Pakkasjärvi N, Ripatti L, Läckgren G, Krishnan N, Anand S
J Pediatr Urol 2023 Dec;19(6):804-811. Epub 2023 Aug 15 doi: 10.1016/j.jpurol.2023.08.008. PMID: 37633825
Khondker A, Kim K, Najafabadi BT, Nguyen DD, Kim JK, Yadav P, Brownrigg N, Richter J, E Chua M, Dos Santos J, Rickard M, Lorenzo AJ
World J Urol 2023 Jul;41(7):1803-1811. Epub 2023 Jun 17 doi: 10.1007/s00345-023-04451-7. PMID: 37330439
Williams G, Craig JC
Cochrane Database Syst Rev 2019 Apr 1;4(4):CD001534. doi: 10.1002/14651858.CD001534.pub4. PMID: 30932167Free PMC Article
Weitz M, Schmidt M
Eur J Pediatr 2017 Jan;176(1):1-9. Epub 2016 Nov 25 doi: 10.1007/s00431-016-2818-3. PMID: 27888411
Larcombe J
BMJ Clin Evid 2010 Feb 9;2010 PMID: 21733199Free PMC Article

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