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Vesicoureteral reflux 4(VUR4)

MedGen UID:
482069
Concept ID:
C3280439
Disease or Syndrome
Synonym: VUR4
 
Monarch Initiative: MONDO:0013682
OMIM®: 614317

Professional guidelines

PubMed

Puri P, Granata C
J Urol 1998 Sep;160(3 Pt 2):1007-11; discussion 1038. doi: 10.1097/00005392-199809020-00011. PMID: 9719265

Recent clinical studies

Etiology

Boswell TC, Maric T, Khoury AE, Farrugia MK
J Pediatr Urol 2023 Aug;19(4):450-455. Epub 2023 May 3 doi: 10.1016/j.jpurol.2023.04.038. PMID: 37188600
Hewitt I, Montini G
Pediatr Nephrol 2021 Apr;36(4):1011-1017. Epub 2020 Apr 22 doi: 10.1007/s00467-020-04573-9. PMID: 32323004
Bastos JM Netto, Rondon AV, Machado MG, Zerati M Filho, Nascimento RLP, Lima SVC, Calado AA, Barroso U Jr
Int Braz J Urol 2020 Jul-Aug;46(4):523-537. doi: 10.1590/S1677-5538.IBJU.2019.0401. PMID: 32167732Free PMC Article
Arlen AM, Cooper CS
Int J Urol 2019 Apr;26(4):440-445. Epub 2019 Feb 14 doi: 10.1111/iju.13915. PMID: 30762254
Cara-Fuentes G, Gupta N, Garin EH
Pediatr Nephrol 2015 May;30(5):703-6. Epub 2014 Dec 11 doi: 10.1007/s00467-014-3021-2. PMID: 25503325

Diagnosis

Hari P, Meena J, Kumar M, Sinha A, Thergaonkar RW, Iyengar A, Khandelwal P, Ekambaram S, Pais P, Sharma J, Kanitkar M, Bagga A; Indian Society of Pediatric Nephrology
Pediatr Nephrol 2024 May;39(5):1639-1668. Epub 2023 Oct 28 doi: 10.1007/s00467-023-06173-9. PMID: 37897526
Boswell TC, Maric T, Khoury AE, Farrugia MK
J Pediatr Urol 2023 Aug;19(4):450-455. Epub 2023 May 3 doi: 10.1016/j.jpurol.2023.04.038. PMID: 37188600
Herthelius M
Pediatr Nephrol 2023 Oct;38(10):3221-3227. Epub 2023 Mar 15 doi: 10.1007/s00467-023-05907-z. PMID: 36920569Free PMC Article
Hewitt I, Montini G
Pediatr Nephrol 2021 Apr;36(4):1011-1017. Epub 2020 Apr 22 doi: 10.1007/s00467-020-04573-9. PMID: 32323004
Cendron M
J Pediatr Urol 2008 Dec;4(6):414-21. Epub 2008 Sep 4 doi: 10.1016/j.jpurol.2008.04.009. PMID: 18775677

Therapy

Morello W, Baskin E, Jankauskiene A, Yalcinkaya F, Zurowska A, Puccio G, Serafinelli J, La Manna A, Krzemień G, Pennesi M, La Scola C, Becherucci F, Brugnara M, Yuksel S, Mekahli D, Chimenz R, De Palma D, Zucchetta P, Vajauskas D, Drozdz D, Szczepanska M, Caliskan S, Lombet J, Minoli DG, Guarino S, Gulleroglu K, Ruzgiene D, Szmigielska A, Barbi E, Ozcakar ZB, Kranz A, Pasini A, Materassi M, De Rechter S, Ariceta G, Weber LT, Marzuillo P, Alberici I, Taranta-Janusz K, Caldas Afonso A, Tkaczyk M, Català M, Cabrera Sevilla JE, Mehls O, Schaefer F, Montini G; PREDICT Study Group
N Engl J Med 2023 Sep 14;389(11):987-997. Epub 2023 Sep 12 doi: 10.1056/NEJMoa2300161. PMID: 37702442
Herthelius M
Pediatr Nephrol 2023 Oct;38(10):3221-3227. Epub 2023 Mar 15 doi: 10.1007/s00467-023-05907-z. PMID: 36920569Free PMC Article
Hewitt I, Montini G
Pediatr Nephrol 2021 Apr;36(4):1011-1017. Epub 2020 Apr 22 doi: 10.1007/s00467-020-04573-9. PMID: 32323004
Williams G, Craig JC
Cochrane Database Syst Rev 2019 Apr 1;4(4):CD001534. doi: 10.1002/14651858.CD001534.pub4. PMID: 30932167Free PMC Article
Keren R, Shaikh N, Pohl H, Gravens-Mueller L, Ivanova A, Zaoutis L, Patel M, deBerardinis R, Parker A, Bhatnagar S, Haralam MA, Pope M, Kearney D, Sprague B, Barrera R, Viteri B, Egigueron M, Shah N, Hoberman A
Pediatrics 2015 Jul;136(1):e13-21. Epub 2015 Jun 8 doi: 10.1542/peds.2015-0409. PMID: 26055855Free PMC Article

Prognosis

Herthelius M
Pediatr Nephrol 2023 Oct;38(10):3221-3227. Epub 2023 Mar 15 doi: 10.1007/s00467-023-05907-z. PMID: 36920569Free PMC Article
Kurt-Sukur ED, Özçakar ZB, Haznedar-Karakaya P, Yılmaz S, Elhan AH, Çakar N, Yalçınkaya F
Arch Argent Pediatr 2020 Feb;118(1):e16-e21. doi: 10.5546/aap.2020.eng.e16. PMID: 31984697
Arlen AM, Cooper CS
Int J Urol 2019 Apr;26(4):440-445. Epub 2019 Feb 14 doi: 10.1111/iju.13915. PMID: 30762254
Molenaar NM, Minnee RC, Bemelman FJ, Idu MM
Prog Transplant 2017 Jun;27(2):196-199. Epub 2017 Mar 22 doi: 10.1177/1526924817699965. PMID: 28617157
Keren R, Shaikh N, Pohl H, Gravens-Mueller L, Ivanova A, Zaoutis L, Patel M, deBerardinis R, Parker A, Bhatnagar S, Haralam MA, Pope M, Kearney D, Sprague B, Barrera R, Viteri B, Egigueron M, Shah N, Hoberman A
Pediatrics 2015 Jul;136(1):e13-21. Epub 2015 Jun 8 doi: 10.1542/peds.2015-0409. PMID: 26055855Free PMC Article

Clinical prediction guides

Morello W, Baskin E, Jankauskiene A, Yalcinkaya F, Zurowska A, Puccio G, Serafinelli J, La Manna A, Krzemień G, Pennesi M, La Scola C, Becherucci F, Brugnara M, Yuksel S, Mekahli D, Chimenz R, De Palma D, Zucchetta P, Vajauskas D, Drozdz D, Szczepanska M, Caliskan S, Lombet J, Minoli DG, Guarino S, Gulleroglu K, Ruzgiene D, Szmigielska A, Barbi E, Ozcakar ZB, Kranz A, Pasini A, Materassi M, De Rechter S, Ariceta G, Weber LT, Marzuillo P, Alberici I, Taranta-Janusz K, Caldas Afonso A, Tkaczyk M, Català M, Cabrera Sevilla JE, Mehls O, Schaefer F, Montini G; PREDICT Study Group
N Engl J Med 2023 Sep 14;389(11):987-997. Epub 2023 Sep 12 doi: 10.1056/NEJMoa2300161. PMID: 37702442
Herthelius M
Pediatr Nephrol 2023 Oct;38(10):3221-3227. Epub 2023 Mar 15 doi: 10.1007/s00467-023-05907-z. PMID: 36920569Free PMC Article
Arlen AM, Cooper CS
Int J Urol 2019 Apr;26(4):440-445. Epub 2019 Feb 14 doi: 10.1111/iju.13915. PMID: 30762254
Keren R, Shaikh N, Pohl H, Gravens-Mueller L, Ivanova A, Zaoutis L, Patel M, deBerardinis R, Parker A, Bhatnagar S, Haralam MA, Pope M, Kearney D, Sprague B, Barrera R, Viteri B, Egigueron M, Shah N, Hoberman A
Pediatrics 2015 Jul;136(1):e13-21. Epub 2015 Jun 8 doi: 10.1542/peds.2015-0409. PMID: 26055855Free PMC Article
Cara-Fuentes G, Gupta N, Garin EH
Pediatr Nephrol 2015 May;30(5):703-6. Epub 2014 Dec 11 doi: 10.1007/s00467-014-3021-2. PMID: 25503325

Recent systematic reviews

Pakkasjärvi N, Ripatti L, Läckgren G, Krishnan N, Anand S
J Pediatr Urol 2023 Dec;19(6):804-811. Epub 2023 Aug 15 doi: 10.1016/j.jpurol.2023.08.008. PMID: 37633825
Khondker A, Kim K, Najafabadi BT, Nguyen DD, Kim JK, Yadav P, Brownrigg N, Richter J, E Chua M, Dos Santos J, Rickard M, Lorenzo AJ
World J Urol 2023 Jul;41(7):1803-1811. Epub 2023 Jun 17 doi: 10.1007/s00345-023-04451-7. PMID: 37330439
Yang S, Gill PJ, Anwar MR, Nurse K, Mahood Q, Borkhoff CM, Bijelic V, Parkin PC, Mahant S; Canadian Paediatric Inpatient Research Network (PIRN)
JAMA Pediatr 2023 Aug 1;177(8):764-773. doi: 10.1001/jamapediatrics.2023.1387. PMID: 37252727Free PMC Article
Williams G, Craig JC
Cochrane Database Syst Rev 2019 Apr 1;4(4):CD001534. doi: 10.1002/14651858.CD001534.pub4. PMID: 30932167Free PMC Article
Routh JC, Bogaert GA, Kaefer M, Manzoni G, Park JM, Retik AB, Rushton HG, Snodgrass WT, Wilcox DT
Eur Urol 2012 Apr;61(4):773-82. Epub 2012 Jan 11 doi: 10.1016/j.eururo.2012.01.002. PMID: 22264440

Supplemental Content

Table of contents

    Clinical resources

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