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Invasive Breast Lobular Carcinoma, Alveolar Variant

MedGen UID:
474848
•Concept ID:
C3273215
•
Neoplastic Process
Synonym: Invasive Lobular Breast Carcinoma, Alveolar Variant

Definition

A grade I invasive lobular carcinoma of the breast, characterized by the presence of round groups of neoplastic cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInvasive Breast Lobular Carcinoma, Alveolar Variant

Recent clinical studies

Etiology

Pleomorphic lobular carcinoma of the breast: a comparison of cytopathological features with other lobular carcinoma variants.
Ohashi R, Matsubara M, Watarai Y, Yanagihara K, Yamashita K, Tsuchiya SI, Takei H, Naito Z
Cytopathology 2017 Apr;28(2):122-130. Epub 2016 Aug 3 doi: 10.1111/cyt.12362. PMID: 27489086
Pleomorphic variant of invasive lobular carcinoma of the breast.
Weidner N, Semple JP
Hum Pathol 1992 Oct;23(10):1167-71. doi: 10.1016/0046-8177(92)90035-2. PMID: 1398644
c-erbB-2 expression in different histological types of invasive breast carcinoma.
Soomro S, Shousha S, Taylor P, Shepard HM, Feldmann M
J Clin Pathol 1991 Mar;44(3):211-4. doi: 10.1136/jcp.44.3.211. PMID: 1672872Free PMC Article
Alveolar variant of invasive lobular carcinoma of the breast. A tumor rich in estrogen receptors.
Shousha S, Backhous CM, Alaghband-Zadeh J, Burn I
Am J Clin Pathol 1986 Jan;85(1):1-5. doi: 10.1093/ajcp/85.1.1. PMID: 3940412

Diagnosis

Uncommon invasive lobular carcinoma with papillary architecture-clinicopathologic and molecular characterization with review of the literature.
Gessain G, Joyon N, Petit T, Cotteret S, Lacroix-Triki M
Virchows Arch 2023 Nov;483(5):723-729. Epub 2023 Mar 16 doi: 10.1007/s00428-023-03526-5. PMID: 36928170
Pleomorphic lobular carcinoma of the breast: a comparison of cytopathological features with other lobular carcinoma variants.
Ohashi R, Matsubara M, Watarai Y, Yanagihara K, Yamashita K, Tsuchiya SI, Takei H, Naito Z
Cytopathology 2017 Apr;28(2):122-130. Epub 2016 Aug 3 doi: 10.1111/cyt.12362. PMID: 27489086
Pleomorphic variant of invasive lobular carcinoma of the breast.
Weidner N, Semple JP
Hum Pathol 1992 Oct;23(10):1167-71. doi: 10.1016/0046-8177(92)90035-2. PMID: 1398644
Alveolar variant of invasive lobular carcinoma of the breast. A tumor rich in estrogen receptors.
Shousha S, Backhous CM, Alaghband-Zadeh J, Burn I
Am J Clin Pathol 1986 Jan;85(1):1-5. doi: 10.1093/ajcp/85.1.1. PMID: 3940412
Invasive lobular carcinoma of the breast: incidence and variants.
Martinez V, Azzopardi JG
Histopathology 1979 Nov;3(6):467-88. doi: 10.1111/j.1365-2559.1979.tb03029.x. PMID: 229072

Prognosis

Pleomorphic variant of invasive lobular carcinoma of the breast.
Weidner N, Semple JP
Hum Pathol 1992 Oct;23(10):1167-71. doi: 10.1016/0046-8177(92)90035-2. PMID: 1398644
c-erbB-2 expression in different histological types of invasive breast carcinoma.
Soomro S, Shousha S, Taylor P, Shepard HM, Feldmann M
J Clin Pathol 1991 Mar;44(3):211-4. doi: 10.1136/jcp.44.3.211. PMID: 1672872Free PMC Article
Invasive lobular carcinomas of the breast--the prognosis of histopathological subtypes.
du Toit RS, Locker AP, Ellis IO, Elston CW, Nicholson RI, Blamey RW
Br J Cancer 1989 Oct;60(4):605-9. doi: 10.1038/bjc.1989.323. PMID: 2803932Free PMC Article
Alveolar variant of invasive lobular carcinoma of the breast. A tumor rich in estrogen receptors.
Shousha S, Backhous CM, Alaghband-Zadeh J, Burn I
Am J Clin Pathol 1986 Jan;85(1):1-5. doi: 10.1093/ajcp/85.1.1. PMID: 3940412

Clinical prediction guides

Alveolar variant of invasive lobular carcinoma of the breast. A tumor rich in estrogen receptors.
Shousha S, Backhous CM, Alaghband-Zadeh J, Burn I
Am J Clin Pathol 1986 Jan;85(1):1-5. doi: 10.1093/ajcp/85.1.1. PMID: 3940412

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