U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Appendix High Grade Intraepithelial Neoplasia

MedGen UID:
474398
•Concept ID:
C3272765
•
Neoplastic Process
Synonyms: Appendiceal High Grade Dysplasia; Appendiceal High Grade Intraepithelial Neoplasia; Appendix High Grade Dysplasia

Definition

A precancerous intraepithelial neoplastic lesion that affects the appendix. It is characterized by the presence of moderate or severe dysplasia and complex architectural alterations of the mucosal epithelium. There is no evidence of invasion. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAppendix High Grade Intraepithelial Neoplasia

Professional guidelines

PubMed

Chemoprevention of breast cancer. A joint guideline from the Canadian Task Force on Preventive Health Care and the Canadian Breast Cancer Initiative's Steering Committee on Clinical Practice Guidelines for the Care and Treatment of Breast Cancer.
Levine M, Moutquin JM, Walton R, Feightner J; Canadian Task Force on Preventive Health Care and the Canadian Breast Cancer Initiative's Steering Committee on Clinical Practice Guidelines for the Care and Treatment of Breast Cancer
CMAJ 2001 Jun 12;164(12):1681-90. PMID: 11450210Free PMC Article

Recent clinical studies

Therapy

Surgery versus radical endotherapies for early cancer and high-grade dysplasia in Barrett's oesophagus.
Bennett C, Green S, DeCaestecker J, Almond M, Barr H, Bhandari P, Ragunath K, Singh R, Jankowski J
Cochrane Database Syst Rev 2020 May 22;5(5):CD007334. doi: 10.1002/14651858.CD007334.pub5. PMID: 32442322Free PMC Article
Population-level impact and herd effects following the introduction of human papillomavirus vaccination programmes: updated systematic review and meta-analysis.
Drolet M, Bénard É, Pérez N, Brisson M; HPV Vaccination Impact Study Group
Lancet 2019 Aug 10;394(10197):497-509. Epub 2019 Jun 26 doi: 10.1016/S0140-6736(19)30298-3. PMID: 31255301Free PMC Article
Surgery versus radical endotherapies for early cancer and high-grade dysplasia in Barrett's oesophagus.
Bennett C, Green S, Decaestecker J, Almond M, Barr H, Bhandari P, Ragunath K, Singh R, Jankowski J
Cochrane Database Syst Rev 2012 Nov 14;11:CD007334. doi: 10.1002/14651858.CD007334.pub4. PMID: 23152243
Surgery versus radical endotherapies for early cancer and high grade dysplasia in Barrett's oesophagus.
Bennett C, Green S, Barr H, Bhandari P, Decaestecker J, Ragunath K, Singh R, Tawil A, Jankowski J
Cochrane Database Syst Rev 2010 May 12;(5):CD007334. doi: 10.1002/14651858.CD007334.pub3. PMID: 20464752
Surgery versus radical endotherapies for early cancer and high grade dysplasia in Barrett's oesophagus.
Green S, Tawil A, Barr H, Bennett C, Bhandari P, Decaestecker J, Ragunath K, Singh R, Jankowski J
Cochrane Database Syst Rev 2009 Apr 15;(2):CD007334. doi: 10.1002/14651858.CD007334.pub2. PMID: 19370683

Prognosis

Population-level impact and herd effects following the introduction of human papillomavirus vaccination programmes: updated systematic review and meta-analysis.
Drolet M, Bénard É, Pérez N, Brisson M; HPV Vaccination Impact Study Group
Lancet 2019 Aug 10;394(10197):497-509. Epub 2019 Jun 26 doi: 10.1016/S0140-6736(19)30298-3. PMID: 31255301Free PMC Article

Clinical prediction guides

Diagnostic usefulness of SpyGlass in intracholecystic papillary neoplasm with pancreaticobiliary maljunction: a case report and comparison with conventional gallbladder cancer with pancreaticobiliary maljunction.
Akita M, Yanagimoto H, Tsugawa D, Ajiki T, Masuda A, Komatsu M, Goto T, Kido M, Toyama H, Fukumoto T
Clin J Gastroenterol 2023 Jun;16(3):476-481. Epub 2023 Mar 3 doi: 10.1007/s12328-023-01778-x. PMID: 36867354

Recent systematic reviews

Surgery versus radical endotherapies for early cancer and high-grade dysplasia in Barrett's oesophagus.
Bennett C, Green S, DeCaestecker J, Almond M, Barr H, Bhandari P, Ragunath K, Singh R, Jankowski J
Cochrane Database Syst Rev 2020 May 22;5(5):CD007334. doi: 10.1002/14651858.CD007334.pub5. PMID: 32442322Free PMC Article
Population-level impact and herd effects following the introduction of human papillomavirus vaccination programmes: updated systematic review and meta-analysis.
Drolet M, Bénard É, Pérez N, Brisson M; HPV Vaccination Impact Study Group
Lancet 2019 Aug 10;394(10197):497-509. Epub 2019 Jun 26 doi: 10.1016/S0140-6736(19)30298-3. PMID: 31255301Free PMC Article
Surgery versus radical endotherapies for early cancer and high-grade dysplasia in Barrett's oesophagus.
Bennett C, Green S, Decaestecker J, Almond M, Barr H, Bhandari P, Ragunath K, Singh R, Jankowski J
Cochrane Database Syst Rev 2012 Nov 14;11:CD007334. doi: 10.1002/14651858.CD007334.pub4. PMID: 23152243
Surgery versus radical endotherapies for early cancer and high grade dysplasia in Barrett's oesophagus.
Bennett C, Green S, Barr H, Bhandari P, Decaestecker J, Ragunath K, Singh R, Tawil A, Jankowski J
Cochrane Database Syst Rev 2010 May 12;(5):CD007334. doi: 10.1002/14651858.CD007334.pub3. PMID: 20464752
Surgery versus radical endotherapies for early cancer and high grade dysplasia in Barrett's oesophagus.
Green S, Tawil A, Barr H, Bennett C, Bhandari P, Decaestecker J, Ragunath K, Singh R, Jankowski J
Cochrane Database Syst Rev 2009 Apr 15;(2):CD007334. doi: 10.1002/14651858.CD007334.pub2. PMID: 19370683

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...