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Buschke Lowenstein tumor(GCBL)

MedGen UID:
473018
Concept ID:
C0276264
Neoplastic Process
Synonyms: GCBL; Giant condyloma acuminatum involving the prepuce and glans penis
SNOMED CT: Anogenital verrucous carcinoma of Buschke-Löwenstein (402910001); Buschke-Löwenstein tumor of penis (402911002); Buschke-Löwenstein giant condyloma (402910001); Giant acuminate warts (402910001); Anogenital verrucous carcinoma of Buschke-Lowenstein (402910001)
 
Monarch Initiative: MONDO:0027026

Definition

A slow-growing, locally destructive, cauliflower-like condyloma of the anogenital region. It most often appears on the penis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBuschke Lowenstein tumor

Professional guidelines

PubMed

Fawaz B, Vieira C, Decker A, Lawrence N
J Dermatolog Treat 2022 Jun;33(4):1811-1815. Epub 2022 Jun 13 doi: 10.1080/09546634.2021.1914312. PMID: 33849379
Sonthalia S, Gandhi V, Agrawal M, Sharma P
Int J STD AIDS 2019 Oct;30(11):1136-1139. Epub 2019 Sep 24 doi: 10.1177/0956462419855505. PMID: 31551001
Fanget F, Pasquer A, Djeudji F, Chabanon J, Barth X
Dig Surg 2017;34(3):247-252. Epub 2016 Dec 10 doi: 10.1159/000452496. PMID: 27941342

Recent clinical studies

Etiology

Purzycka-Bohdan D, Nowicki RJ, Herms F, Casanova JL, Fouéré S, Béziat V
Int J Mol Sci 2022 Apr 20;23(9) doi: 10.3390/ijms23094547. PMID: 35562936Free PMC Article
Nieves-Condoy JF, Acuña-Pinzón CL, Chavarría-Chavira JL, Hinojosa-Ugarte D, Zúñiga-Vázquez LA
Infect Dis Obstet Gynecol 2021;2021:9919446. Epub 2021 Jun 30 doi: 10.1155/2021/9919446. PMID: 34305393Free PMC Article
Zhang D, Gonzalez RS, Feely M, Umrau K, Lee H, Allende DS, Karamchandani DM, Zaleski M, Lin J, Westerhoff M, Zhang X, Alpert L, Liao X, Lai J, Liu X
Virchows Arch 2020 Apr;476(4):543-550. Epub 2019 Nov 15 doi: 10.1007/s00428-019-02680-z. PMID: 31728626
Ben Kridis W, Werda I, Charfi S, Toumi N, Boudawara T, Mzali R, Daoud J, Khanfir A
Exp Oncol 2019 Jun;41(2):182-184. doi: 10.32471/exp-oncology.2312-8852.vol-41-no-2.13119. PMID: 31262155
Spinu D, Rădulescu A, Bratu O, Checheriţă IA, Ranetti AE, Mischianu D; -
Chirurgia (Bucur) 2014 Jul-Aug;109(4):445-50. PMID: 25149605

Diagnosis

Ye Q, Jia M, Deng LJ, Fang S
J Cutan Med Surg 2023 Mar-Apr;27(2):150-156. Epub 2023 Feb 14 doi: 10.1177/12034754231155895. PMID: 36789508
Nieves-Condoy JF, Acuña-Pinzón CL, Chavarría-Chavira JL, Hinojosa-Ugarte D, Zúñiga-Vázquez LA
Infect Dis Obstet Gynecol 2021;2021:9919446. Epub 2021 Jun 30 doi: 10.1155/2021/9919446. PMID: 34305393Free PMC Article
Ben Kridis W, Werda I, Charfi S, Toumi N, Boudawara T, Mzali R, Daoud J, Khanfir A
Exp Oncol 2019 Jun;41(2):182-184. doi: 10.32471/exp-oncology.2312-8852.vol-41-no-2.13119. PMID: 31262155
Rodríguez-Gutiérrez R, Rodarte-Shade M, González-Saldivar G, González-González JG
Am J Med Sci 2015 Jan;349(1):e1. doi: 10.1097/MAJ.0000000000000413. PMID: 25535884
Pinto AR, Guedes-Martins L, Marques C, Cabral JM
Acta Med Port 2012 Sep-Oct;25(5):345-7. Epub 2012 Nov 12 PMID: 23211208

Therapy

Zhang D, Gonzalez RS, Feely M, Umrau K, Lee H, Allende DS, Karamchandani DM, Zaleski M, Lin J, Westerhoff M, Zhang X, Alpert L, Liao X, Lai J, Liu X
Virchows Arch 2020 Apr;476(4):543-550. Epub 2019 Nov 15 doi: 10.1007/s00428-019-02680-z. PMID: 31728626
Sonthalia S, Gandhi V, Agrawal M, Sharma P
Int J STD AIDS 2019 Oct;30(11):1136-1139. Epub 2019 Sep 24 doi: 10.1177/0956462419855505. PMID: 31551001
Ben Kridis W, Werda I, Charfi S, Toumi N, Boudawara T, Mzali R, Daoud J, Khanfir A
Exp Oncol 2019 Jun;41(2):182-184. doi: 10.32471/exp-oncology.2312-8852.vol-41-no-2.13119. PMID: 31262155
Rodríguez-Gutiérrez R, Rodarte-Shade M, González-Saldivar G, González-González JG
Am J Med Sci 2015 Jan;349(1):e1. doi: 10.1097/MAJ.0000000000000413. PMID: 25535884
McDuffie RW
Urology 1975 Sep;6(3):397-8. doi: 10.1016/0090-4295(75)90783-9. PMID: 1162826

Prognosis

Cimmino A, Walters E, Gubler A, Ibrahim A
Am J Case Rep 2020 Feb 23;21:e920516. doi: 10.12659/AJCR.920516. PMID: 32088723Free PMC Article
Zhang D, Gonzalez RS, Feely M, Umrau K, Lee H, Allende DS, Karamchandani DM, Zaleski M, Lin J, Westerhoff M, Zhang X, Alpert L, Liao X, Lai J, Liu X
Virchows Arch 2020 Apr;476(4):543-550. Epub 2019 Nov 15 doi: 10.1007/s00428-019-02680-z. PMID: 31728626
Bowman IA, Parra A, Arriaga Y
J Oncol Pract 2016 Oct;12(10):951-953. doi: 10.1200/JOP.2016.013441. PMID: 27554523
Frega A, Stentella P, Tinari A, Vecchione A, Marchionni M
Anticancer Res 2002 Mar-Apr;22(2B):1201-4. PMID: 12168925
Chu QD, Vezeridis MP, Libbey NP, Wanebo HJ
Dis Colon Rectum 1994 Sep;37(9):950-7. doi: 10.1007/BF02052606. PMID: 8076499

Clinical prediction guides

Saldivar-Reyes DA, Muñoz-Maldonado GE, Fernández-Treviño JR, Vidal-Torres Ó, Medina-Muñoz DE
Cir Cir 2023;91(6):835-838. doi: 10.24875/CIRU.22000302. PMID: 38096879
Taskin OC, Pehlivanoglu B, Reid MD, Friedman T, Lee M, Tadros TS, Bandyopadhyay S, Akinfolarin J, Armutlu A, Basturk O, Adsay V
Turk Patoloji Derg 2021;37(1):18-25. doi: 10.5146/tjpath.2020.01508. PMID: 33021736Free PMC Article
Zhang D, Gonzalez RS, Feely M, Umrau K, Lee H, Allende DS, Karamchandani DM, Zaleski M, Lin J, Westerhoff M, Zhang X, Alpert L, Liao X, Lai J, Liu X
Virchows Arch 2020 Apr;476(4):543-550. Epub 2019 Nov 15 doi: 10.1007/s00428-019-02680-z. PMID: 31728626
Ali Sbai M, Balti W, Dhahak S, Ben Romdhane S, Tabib M, Balti H
Tunis Med 2009 Sep;87(9):627-9. PMID: 20180387
Asato Y, Taira K, Yamamoto Y, Uezato H
Eur J Dermatol 2008 May-Jun;18(3):329-31. Epub 2008 May 13 doi: 10.1684/ejd.2008.0398. PMID: 18474465

Recent systematic reviews

Ates M, Akbulut S, Tuncer A, Sahin E, Karabulut E, Sarici KB
J Gastrointest Cancer 2022 Dec;53(4):1083-1092. Epub 2021 Oct 25 doi: 10.1007/s12029-021-00713-y. PMID: 34694593

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