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Lymphoblastic lymphoma

MedGen UID:
42541
Concept ID:
C0079748
Neoplastic Process
Synonyms: Lymphoblastic Lymphoma; lymphoblastic lymphoma; Lymphoblastic lymphosarcoma; Lymphoblastoma; lymphoma, lymphoblastic; lymphoma, lymphoblastic, malignant; Malignant lymphoblastic lymphoma; Malignant lymphoma, lymphoblastic; Precursor cell lymphoblastic lymphoma; Precursor Cell Lymphoblastic Lymphoma; precursor cell lymphoblastic lymphoma; Precursor Lymphoblastic Lymphoma; precursor lymphoblastic lymphoma
SNOMED CT: Malignant lymphoma, lymphoblastic (128806000); Precursor cell lymphoblastic lymphoma (128806000); Lymphoblastic lymphosarcoma (188675007); Precursor cell lymphoblastic lymphoma (1217301006); Lymphoblastoma (1217301006); Malignant lymphoblastic lymphoma (1217301006)
 
Monarch Initiative: MONDO:0000873

Definition

A lymphoma composed of immature small to medium-sized precursor lymphoid cells (lymphoblasts). It includes the B- and T-cell lymphoblastic lymphoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLymphoblastic lymphoma

Professional guidelines

PubMed

Shimony S, DeAngelo DJ, Luskin MR
Blood Adv 2024 Jan 9;8(1):23-36. doi: 10.1182/bloodadvances.2023010303. PMID: 37389830Free PMC Article
Temple WC, Mueller S, Hermiston ML, Burkhardt B
Best Pract Res Clin Haematol 2023 Mar;36(1):101449. Epub 2023 Feb 16 doi: 10.1016/j.beha.2023.101449. PMID: 36907639
Zhang ML, Sohani AR
Semin Diagn Pathol 2020 Jul;37(4):156-165. Epub 2020 May 15 doi: 10.1053/j.semdp.2020.04.005. PMID: 32451144

Curated

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) B-Cell Lymphomas, 2024

Recent clinical studies

Etiology

Si Lim SJ, Ford JB, Hermiston ML
Blood 2023 Jun 22;141(25):3019-3030. doi: 10.1182/blood.2022016503. PMID: 37018730
Duffield AS, Mullighan CG, Borowitz MJ
Virchows Arch 2023 Jan;482(1):11-26. Epub 2022 Nov 24 doi: 10.1007/s00428-022-03448-8. PMID: 36422706Free PMC Article
Intermesoli T, Weber A, Leoncin M, Frison L, Skert C, Bassan R
Curr Oncol Rep 2022 Jan;24(1):1-12. Epub 2022 Jan 20 doi: 10.1007/s11912-021-01168-x. PMID: 35059993
Vrooman LM, Blonquist TM, Stevenson KE, Supko JG, Hunt SK, Cronholm SM, Koch V, Kay-Green S, Athale UH, Clavell LA, Cole PD, Harris MH, Kelly KM, Laverdiere C, Leclerc JM, Michon B, Place AE, Schorin MA, Welch JJG, Neuberg DS, Sallan SE, Silverman LB
J Clin Oncol 2021 Nov 1;39(31):3496-3505. Epub 2021 Jul 6 doi: 10.1200/JCO.20.03692. PMID: 34228505
Teachey DT, O'Connor D
Blood 2020 Jan 16;135(3):159-166. doi: 10.1182/blood.2019001557. PMID: 31738819Free PMC Article

Diagnosis

Si Lim SJ, Ford JB, Hermiston ML
Blood 2023 Jun 22;141(25):3019-3030. doi: 10.1182/blood.2022016503. PMID: 37018730
Temple WC, Mueller S, Hermiston ML, Burkhardt B
Best Pract Res Clin Haematol 2023 Mar;36(1):101449. Epub 2023 Feb 16 doi: 10.1016/j.beha.2023.101449. PMID: 36907639
Duffield AS, Mullighan CG, Borowitz MJ
Virchows Arch 2023 Jan;482(1):11-26. Epub 2022 Nov 24 doi: 10.1007/s00428-022-03448-8. PMID: 36422706Free PMC Article
Intermesoli T, Weber A, Leoncin M, Frison L, Skert C, Bassan R
Curr Oncol Rep 2022 Jan;24(1):1-12. Epub 2022 Jan 20 doi: 10.1007/s11912-021-01168-x. PMID: 35059993
Luca DC
Clin Lab Med 2021 Sep;41(3):405-416. doi: 10.1016/j.cll.2021.04.003. PMID: 34304772

Therapy

Whitlock JA, Malvar J, Dalla-Pozza L, Goldberg JM, Silverman LB, Ziegler DS, Attarbaschi A, Brown PA, Gardner RA, Gaynon PS, Hutchinson R, Huynh VT, Jeha S, Marcus L, Messinger Y, Schultz KR, Cassar J, Locatelli F, Zwaan CM, Wood BL, Sposto R, Gore L
Pediatr Blood Cancer 2022 Nov;69(11):e29901. Epub 2022 Aug 21 doi: 10.1002/pbc.29901. PMID: 35989458
Teachey DT, Devidas M, Wood BL, Chen Z, Hayashi RJ, Hermiston ML, Annett RD, Archer JH, Asselin BL, August KJ, Cho SY, Dunsmore KP, Fisher BT, Freedman JL, Galardy PJ, Harker-Murray P, Horton TM, Jaju AI, Lam A, Messinger YH, Miles RR, Okada M, Patel SI, Schafer ES, Schechter T, Singh N, Steele AC, Sulis ML, Vargas SL, Winter SS, Wood C, Zweidler-McKay P, Bollard CM, Loh ML, Hunger SP, Raetz EA
J Clin Oncol 2022 Jul 1;40(19):2106-2118. Epub 2022 Mar 10 doi: 10.1200/JCO.21.02678. PMID: 35271306Free PMC Article
Pullarkat VA, Lacayo NJ, Jabbour E, Rubnitz JE, Bajel A, Laetsch TW, Leonard J, Colace SI, Khaw SL, Fleming SA, Mattison RJ, Norris R, Opferman JT, Roberts KG, Zhao Y, Qu C, Badawi M, Schmidt M, Tong B, Pesko JC, Sun Y, Ross JA, Vishwamitra D, Rosenwinkel L, Kim SY, Jacobson A, Mullighan CG, Alexander TB, Stock W
Cancer Discov 2021 Jun;11(6):1440-1453. Epub 2021 Feb 16 doi: 10.1158/2159-8290.CD-20-1465. PMID: 33593877Free PMC Article
Cortelazzo S, Ferreri A, Hoelzer D, Ponzoni M
Crit Rev Oncol Hematol 2017 May;113:304-317. Epub 2017 Mar 18 doi: 10.1016/j.critrevonc.2017.03.020. PMID: 28427520
Garcia-Manero G, Kantarjian HM
Hematol Oncol Clin North Am 2000 Dec;14(6):1381-96, x-xi. doi: 10.1016/s0889-8588(05)70192-1. PMID: 11147229

Prognosis

Si Lim SJ, Ford JB, Hermiston ML
Blood 2023 Jun 22;141(25):3019-3030. doi: 10.1182/blood.2022016503. PMID: 37018730
Temple WC, Mueller S, Hermiston ML, Burkhardt B
Best Pract Res Clin Haematol 2023 Mar;36(1):101449. Epub 2023 Feb 16 doi: 10.1016/j.beha.2023.101449. PMID: 36907639
Intermesoli T, Weber A, Leoncin M, Frison L, Skert C, Bassan R
Curr Oncol Rep 2022 Jan;24(1):1-12. Epub 2022 Jan 20 doi: 10.1007/s11912-021-01168-x. PMID: 35059993
Luca DC
Clin Lab Med 2021 Sep;41(3):405-416. doi: 10.1016/j.cll.2021.04.003. PMID: 34304772
Burkhardt B, Hermiston ML
Br J Haematol 2019 Jun;185(6):1158-1170. Epub 2019 Feb 27 doi: 10.1111/bjh.15793. PMID: 30809797

Clinical prediction guides

Maese L, Loh ML, Choi MR, Lin T, Aoki E, Zanette M, Agarwal S, Iannone R, Silverman JA, Silverman LB, Raetz EA, Rau RE
Blood 2023 Feb 16;141(7):704-712. doi: 10.1182/blood.2022016923. PMID: 36108304Free PMC Article
Intermesoli T, Weber A, Leoncin M, Frison L, Skert C, Bassan R
Curr Oncol Rep 2022 Jan;24(1):1-12. Epub 2022 Jan 20 doi: 10.1007/s11912-021-01168-x. PMID: 35059993
Vrooman LM, Blonquist TM, Stevenson KE, Supko JG, Hunt SK, Cronholm SM, Koch V, Kay-Green S, Athale UH, Clavell LA, Cole PD, Harris MH, Kelly KM, Laverdiere C, Leclerc JM, Michon B, Place AE, Schorin MA, Welch JJG, Neuberg DS, Sallan SE, Silverman LB
J Clin Oncol 2021 Nov 1;39(31):3496-3505. Epub 2021 Jul 6 doi: 10.1200/JCO.20.03692. PMID: 34228505
Pullarkat VA, Lacayo NJ, Jabbour E, Rubnitz JE, Bajel A, Laetsch TW, Leonard J, Colace SI, Khaw SL, Fleming SA, Mattison RJ, Norris R, Opferman JT, Roberts KG, Zhao Y, Qu C, Badawi M, Schmidt M, Tong B, Pesko JC, Sun Y, Ross JA, Vishwamitra D, Rosenwinkel L, Kim SY, Jacobson A, Mullighan CG, Alexander TB, Stock W
Cancer Discov 2021 Jun;11(6):1440-1453. Epub 2021 Feb 16 doi: 10.1158/2159-8290.CD-20-1465. PMID: 33593877Free PMC Article
Hayashi RJ, Winter SS, Dunsmore KP, Devidas M, Chen Z, Wood BL, Hermiston ML, Teachey DT, Perkins SL, Miles RR, Raetz EA, Loh ML, Winick NJ, Carroll WL, Hunger SP, Lim MS, Gross TG, Bollard CM
J Clin Oncol 2020 Sep 10;38(26):3062-3070. Epub 2020 Jun 17 doi: 10.1200/JCO.20.00531. PMID: 32552472Free PMC Article

Recent systematic reviews

Lynggaard LS, Rank CU, Als-Nielsen B, Hoejfeldt SG, Heyman M, Schmiegelow K, Albertsen BK
Cochrane Database Syst Rev 2023 May 31;5(5):CD014570. doi: 10.1002/14651858.CD014570.pub2. PMID: 37260073Free PMC Article
Saglam A, Singh K, Gollapudi S, Kumar J, Brar N, Butzmann A, Warnke R, Ohgami RS
Int J Lab Hematol 2022 Aug;44(4):700-711. Epub 2022 May 16 doi: 10.1111/ijlh.13873. PMID: 35577551
Croci DM, Gamboa NT, Osman AEG, Maese L, Mazur M, Bisson EF, Dailey AT
Clin Neurol Neurosurg 2022 Jan;212:107064. Epub 2021 Nov 24 doi: 10.1016/j.clineuro.2021.107064. PMID: 34871993
Huang C, Yu M, Yao X
BMJ Open 2018 May 31;8(5):e018070. doi: 10.1136/bmjopen-2017-018070. PMID: 29858404Free PMC Article

Supplemental Content

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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NCCN, 2024
      NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) B-Cell Lymphomas, 2024

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