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Furunculosis

MedGen UID:
42118
•Concept ID:
C0016867
•
Disease or Syndrome

Definition

A skin condition that is characterized by recurring furuncles, lesions primarily caused by staphylococcus aureus infection of the hair follicles and surrounding skin. Furunculosis occurs more frequently in persons with immune systems disorders than in the general population. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFurunculosis

Professional guidelines

PubMed

Microbiology and management of soft tissue and muscle infections.
Brook I
Int J Surg 2008 Aug;6(4):328-38. Epub 2007 Jul 15 doi: 10.1016/j.ijsu.2007.07.001. PMID: 17720643
Epidemiology, clinical features and management of infections due to community methicillin-resistant Staphylococcus aureus (cMRSA).
Gosbell IB
Intern Med J 2005 Dec;35 Suppl 2:S120-35. doi: 10.1111/j.1444-0903.2005.00985.x. PMID: 16271056
Bacterial skin infections in the elderly: diagnosis and treatment.
Laube S, Farrell AM
Drugs Aging 2002;19(5):331-42. doi: 10.2165/00002512-200219050-00002. PMID: 12093320

Recent clinical studies

Etiology

Interventions for bacterial folliculitis and boils (furuncles and carbuncles).
Lin HS, Lin PT, Tsai YS, Wang SH, Chi CC
Cochrane Database Syst Rev 2021 Feb 26;2(2):CD013099. doi: 10.1002/14651858.CD013099.pub2. PMID: 33634465Free PMC Article
Cutaneous infections in the mature patient.
Castro MCR, Ramos-E-Silva M
Clin Dermatol 2018 Mar-Apr;36(2):188-196. Epub 2017 Oct 3 doi: 10.1016/j.clindermatol.2017.10.010. PMID: 29566923
Recurrent furunculosis: a review of the literature.
Demos M, McLeod MP, Nouri K
Br J Dermatol 2012 Oct;167(4):725-32. doi: 10.1111/j.1365-2133.2012.11151.x. PMID: 22803835
Obesity and dermatology.
Scheinfeld NS
Clin Dermatol 2004 Jul-Aug;22(4):303-9. doi: 10.1016/j.clindermatol.2004.01.001. PMID: 15475230
Fusidic acid in dermatology.
Wilkinson JD
Br J Dermatol 1998 Dec;139 Suppl 53:37-40. doi: 10.1046/j.1365-2133.1998.1390s3037.x. PMID: 9990411

Diagnosis

Interventions for bacterial folliculitis and boils (furuncles and carbuncles).
Lin HS, Lin PT, Tsai YS, Wang SH, Chi CC
Cochrane Database Syst Rev 2021 Feb 26;2(2):CD013099. doi: 10.1002/14651858.CD013099.pub2. PMID: 33634465Free PMC Article
Severe bacterial skin infections.
Marques SA, Abbade LPF
An Bras Dermatol 2020 Jul-Aug;95(4):407-417. Epub 2020 May 16 doi: 10.1016/j.abd.2020.04.003. PMID: 32507327Free PMC Article
Idiopathic granulomatous mastitis.
Haitz K, Ly A, Smith G
Cutis 2019 Jan;103(1):38-42. PMID: 30758334
Recurrent furunculosis: a review of the literature.
Demos M, McLeod MP, Nouri K
Br J Dermatol 2012 Oct;167(4):725-32. doi: 10.1111/j.1365-2133.2012.11151.x. PMID: 22803835
Hidradenitis suppurativa.
Brown TJ, Rosen T, Orengo IF
South Med J 1998 Dec;91(12):1107-14. doi: 10.1097/00007611-199812000-00003. PMID: 9853721

Therapy

Interventions for bacterial folliculitis and boils (furuncles and carbuncles).
Lin HS, Lin PT, Tsai YS, Wang SH, Chi CC
Cochrane Database Syst Rev 2021 Feb 26;2(2):CD013099. doi: 10.1002/14651858.CD013099.pub2. PMID: 33634465Free PMC Article
Cutaneous infections in the mature patient.
Castro MCR, Ramos-E-Silva M
Clin Dermatol 2018 Mar-Apr;36(2):188-196. Epub 2017 Oct 3 doi: 10.1016/j.clindermatol.2017.10.010. PMID: 29566923
Smoker's boils.
Happle R, König A
Dermatology 2011;222(3):282-4. Epub 2011 May 26 doi: 10.1159/000327923. PMID: 21613779
Hidradenitis suppurativa.
Brown TJ, Rosen T, Orengo IF
South Med J 1998 Dec;91(12):1107-14. doi: 10.1097/00007611-199812000-00003. PMID: 9853721
Furunculosis.
Chan KL, Soo G, van Hasselt CA
Ear Nose Throat J 1997 Mar;76(3):126. PMID: 9086637

Prognosis

Acneiform Presentations of Folliculotropic Mycosis Fungoides.
Shamim H, Riemer C, Weenig R, Sokumbi O, Sciallis G, McEvoy M, Mischke D, Comfere N
Am J Dermatopathol 2021 Feb 1;43(2):85-92. doi: 10.1097/DAD.0000000000001698. PMID: 33492839
Erythema ab igne.
Miller K, Hunt R, Chu J, Meehan S, Stein J
Dermatol Online J 2011 Oct 15;17(10):28. PMID: 22031654
Microbiology and management of soft tissue and muscle infections.
Brook I
Int J Surg 2008 Aug;6(4):328-38. Epub 2007 Jul 15 doi: 10.1016/j.ijsu.2007.07.001. PMID: 17720643
Obesity and dermatology.
Scheinfeld NS
Clin Dermatol 2004 Jul-Aug;22(4):303-9. doi: 10.1016/j.clindermatol.2004.01.001. PMID: 15475230
Hidradenitis suppurativa.
Brown TJ, Rosen T, Orengo IF
South Med J 1998 Dec;91(12):1107-14. doi: 10.1097/00007611-199812000-00003. PMID: 9853721

Clinical prediction guides

Acneiform Presentations of Folliculotropic Mycosis Fungoides.
Shamim H, Riemer C, Weenig R, Sokumbi O, Sciallis G, McEvoy M, Mischke D, Comfere N
Am J Dermatopathol 2021 Feb 1;43(2):85-92. doi: 10.1097/DAD.0000000000001698. PMID: 33492839
Self-Reported Pain Alleviating Methods in Patients with Hidradenitis Suppurativa.
Ravn Jørgensen AH, Yao Y, Thomsen SF, Christian Ring H
Actas Dermosifiliogr (Engl Ed) 2021 Feb;112(2):153-158. Epub 2020 Nov 21 doi: 10.1016/j.ad.2020.08.011. PMID: 33232705
Cutaneous infections in the mature patient.
Castro MCR, Ramos-E-Silva M
Clin Dermatol 2018 Mar-Apr;36(2):188-196. Epub 2017 Oct 3 doi: 10.1016/j.clindermatol.2017.10.010. PMID: 29566923
Interventions for acute otitis externa.
Kaushik V, Malik T, Saeed SR
Cochrane Database Syst Rev 2010 Jan 20;(1):CD004740. doi: 10.1002/14651858.CD004740.pub2. PMID: 20091565
Furuncle.
Pinkus H
J Cutan Pathol 1979 Dec;6(6):517-8. doi: 10.1111/j.1600-0560.1979.tb01181.x. PMID: 521543

Recent systematic reviews

Nasal Vestibulitis and Vestibular Furunculosis: a systematic review about two common nasal infections and considerations about correct diagnosis and management.
Marra P, Colacurcio V, De Luca P, Bisogno A, Calvanese M, Scarpa A, Ralli M, De Vincentiis M, Camaioni A, Salzano FA
Clin Ter 2022 Nov-Dec;173(6):590-596. doi: 10.7417/CT.2022.2487. PMID: 36373460
Interventions for bacterial folliculitis and boils (furuncles and carbuncles).
Lin HS, Lin PT, Tsai YS, Wang SH, Chi CC
Cochrane Database Syst Rev 2021 Feb 26;2(2):CD013099. doi: 10.1002/14651858.CD013099.pub2. PMID: 33634465Free PMC Article
Association between prior antibiotic therapy and subsequent risk of community-acquired infections: a systematic review.
Malik U, Armstrong D, Ashworth M, Dregan A, L'Esperance V, McDonnell L, Molokhia M, White P
J Antimicrob Chemother 2018 Feb 1;73(2):287-296. doi: 10.1093/jac/dkx374. PMID: 29149266
Interventions for acute otitis externa.
Kaushik V, Malik T, Saeed SR
Cochrane Database Syst Rev 2010 Jan 20;(1):CD004740. doi: 10.1002/14651858.CD004740.pub2. PMID: 20091565

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