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Vestibular papilloma

MedGen UID:
277874
•Concept ID:
C1336982
•
Neoplastic Process
Synonyms: mammalian vulva squamous papilloma; Vestibular Papilloma; vestibular papilloma; Vulvar Squamous Cell Papilloma; Vulvar Squamous Papilloma; vulvar squamous papilloma
 
Monarch Initiative: MONDO:0002194

Definition

A benign papillary neoplasm that arises from the vulva and is characterized by the presence of a delicate fibrovascular stalk lined by squamous epithelium. There is no evidence of epithelial atypia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVestibular papilloma

Professional guidelines

PubMed

Use of Dermatoscopy in Diagnosing Vestibular Papillomatosis in Pregnancy: An Uncommon Differential of Genital Warts.
Dhattarwal N, Chauhan N, Puri P
Skinmed 2023;21(3):212-213. Epub 2023 Aug 28 PMID: 37634111

Recent clinical studies

Etiology

Modified Endoscopic Denker's Approach for Management of Anterior Maxillary Sinus Tumors: Multicenter Series of 58 Cases.
McCormick JP, Suh JD, Wang EW, DeConde AS, Wang MB, Yang HH, Carle TR, Wung V, Lee JT
Am J Rhinol Allergy 2022 Nov;36(6):763-772. Epub 2022 Jul 5 doi: 10.1177/19458924221110652. PMID: 35791572
Modified midfacial degloving approach for sinonasal tumors.
Cansz H, Tahamiler R, Yener M, Acoğlu E, Güvenç MG, Papila I, Sekercioğlu N
J Craniofac Surg 2008 Nov;19(6):1518-22. doi: 10.1097/SCS.0b013e31818b2ceb. PMID: 19098542
The role of gamma knife radiosurgery in children.
Eder HG, Leber KA, Eustacchio S, Pendl G
Childs Nerv Syst 2001 May;17(6):341-6; discussion 347. doi: 10.1007/s003810000435. PMID: 11417414
Flashlamp-excited dye laser therapy of idiopathic vulvodynia is safe and efficacious.
Reid R, Omoto KH, Precop SL, Berman NR, Rutledge LH, Dean SM, Pleatman M
Am J Obstet Gynecol 1995 Jun;172(6):1684-96; discussion 1696-701. doi: 10.1016/0002-9378(95)91400-5. PMID: 7778621
What is vestibular papillomatosis? A study of its prevalence, aetiology and natural history.
Welch JM, Nayagam M, Parry G, Das R, Campbell M, Whatley J, Bradbeer C
Br J Obstet Gynaecol 1993 Oct;100(10):939-42. doi: 10.1111/j.1471-0528.1993.tb15112.x. PMID: 8217979

Diagnosis

Temporal Bone Tumors: An Imaging Update.
Touska P, Juliano AF
Neuroimaging Clin N Am 2019 Feb;29(1):145-172. doi: 10.1016/j.nic.2018.09.007. PMID: 30466638
Various tumors in the nasal vestibule.
Kim SJ, Byun SW, Lee SS
Int J Clin Exp Pathol 2013;6(12):2713-8. Epub 2013 Nov 15 PMID: 24294358Free PMC Article
Vulvar vestibular papillomatosis.
Wollina U, Verma S
Indian J Dermatol Venereol Leprol 2010 May-Jun;76(3):270-2. doi: 10.4103/0378-6323.62971. PMID: 20445299
Imaging of cerebellopontine angle lesions: an update. Part 2: intra-axial lesions, skull base lesions that may invade the CPA region, and non-enhancing extra-axial lesions.
Bonneville F, Savatovsky J, Chiras J
Eur Radiol 2007 Nov;17(11):2908-20. Epub 2007 Jun 14 doi: 10.1007/s00330-007-0680-4. PMID: 17569053
Benign mucosal tumors of the nose and paranasal sinuses.
Michaels L
Semin Diagn Pathol 1996 May;13(2):113-7. PMID: 8734417

Therapy

Modified midfacial degloving approach for sinonasal tumors.
Cansz H, Tahamiler R, Yener M, Acoğlu E, Güvenç MG, Papila I, Sekercioğlu N
J Craniofac Surg 2008 Nov;19(6):1518-22. doi: 10.1097/SCS.0b013e31818b2ceb. PMID: 19098542
Flashlamp-excited dye laser therapy of idiopathic vulvodynia is safe and efficacious.
Reid R, Omoto KH, Precop SL, Berman NR, Rutledge LH, Dean SM, Pleatman M
Am J Obstet Gynecol 1995 Jun;172(6):1684-96; discussion 1696-701. doi: 10.1016/0002-9378(95)91400-5. PMID: 7778621
Vulvar condylomas and squamous vestibular micropapilloma. Differences in appearance and response to treatment.
Potkul RK, Lancaster WD, Kurman RJ, Lewandowski G, Weck PK, Delgado G
J Reprod Med 1990 Nov;35(11):1019-22. PMID: 2177507

Prognosis

Modified midfacial degloving approach for sinonasal tumors.
Cansz H, Tahamiler R, Yener M, Acoğlu E, Güvenç MG, Papila I, Sekercioğlu N
J Craniofac Surg 2008 Nov;19(6):1518-22. doi: 10.1097/SCS.0b013e31818b2ceb. PMID: 19098542
Vestibular papillae of the vulva.
Prieto MA, Gutiérrez JV, Sambucety PS
Int J Dermatol 2004 Feb;43(2):143-4. doi: 10.1111/j.1365-4632.2004.01863.x. PMID: 15125508
The role of gamma knife radiosurgery in children.
Eder HG, Leber KA, Eustacchio S, Pendl G
Childs Nerv Syst 2001 May;17(6):341-6; discussion 347. doi: 10.1007/s003810000435. PMID: 11417414
Pruritic vulvar squamous papillomatosis: evidence for human papillomavirus etiology.
Growdon WA, Fu YS, Lebherz TB, Rapkin A, Mason GD, Parks G
Obstet Gynecol 1985 Oct;66(4):564-8. PMID: 2995892

Clinical prediction guides

Modified midfacial degloving approach for sinonasal tumors.
Cansz H, Tahamiler R, Yener M, Acoğlu E, Güvenç MG, Papila I, Sekercioğlu N
J Craniofac Surg 2008 Nov;19(6):1518-22. doi: 10.1097/SCS.0b013e31818b2ceb. PMID: 19098542
Focal epithelial hyperplasia (Heck's disease): the first reported case from Italy.
Ficarra G, Adler-Storthz K, Galeotti F, Shillitoe E
Tumori 1991 Feb 28;77(1):83-5. doi: 10.1177/030089169107700119. PMID: 1850180
Pruritic vulvar squamous papillomatosis: evidence for human papillomavirus etiology.
Growdon WA, Fu YS, Lebherz TB, Rapkin A, Mason GD, Parks G
Obstet Gynecol 1985 Oct;66(4):564-8. PMID: 2995892

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